Zobrazeno 1 - 10
of 144
pro vyhledávání: '"Julie A, Mattison"'
Autor:
Hagai Yanai, Bongsoo Park, Hyunwook Koh, Hyo Jung Jang, Kelli L. Vaughan, Mayuri Tanaka-Yano, Miguel Aon, Madison Blanton, Ilhem Messaoudi, Alberto Diaz-Ruiz, Julie A. Mattison, Isabel Beerman
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Dietary restriction has shown benefits in physiological, metabolic, and molecular signatures associated with aging but is a difficult lifestyle to maintain for most individuals. In mice, a less restrictive diet that allows for cyclical perio
Externí odkaz:
https://doaj.org/article/db9957647c4c41dba19b324fff38ec43
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0308007 (2024)
Laboratory animal research with nonhuman primates (NHPs) requires anesthesia for most procedures to ensure safety and consistency in sample collection. However, anesthesia drugs can have adverse effects on the physiological measures of interest. Alfa
Externí odkaz:
https://doaj.org/article/0673daeffffa4d1f81a2389cfbd6c0a9
Autor:
Mary Ann Croft, Jared P Mcdonald, Julie Kiland, Julie A Mattison, George S Roth, Don Ingram, Paul L Kaufman
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0300476 (2024)
PurposeTo determine the effect of sex as a risk factor regarding presbyopia.MethodsMaximum accommodation was pharmacologically induced (40% cabachol corneal iontophoresis) in 97 rhesus monkeys (49 males and 48 females) ranging in age from 8 to 36 yea
Externí odkaz:
https://doaj.org/article/594a3c296ac746c4ad4728a6f7661208
Autor:
Allison B. Herman, Dimitrios Tsitsipatis, Carlos Anerillas, Krystyna Mazan-Mamczarz, Angelica E. Carr, Jordan M. Gregg, Mingyi Wang, Jing Zhang, Marc Michel, Charnae’ A. Henry-Smith, Sophia C. Harris, Rachel Munk, Jennifer L. Martindale, Yulan Piao, Jinshui Fan, Julie A. Mattison, Supriyo De, Kotb Abdelmohsen, Robert W. Maul, Toshiko Tanaka, Ann Zenobia Moore, Megan E. DeMouth, Simone Sidoli, Luigi Ferrucci, Yie Liu, Rafael de Cabo, Edward G. Lakatta, Myriam Gorospe
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 12 (2023)
Senescent vascular smooth muscle cells (VSMCs) accumulate in the vasculature with age and tissue damage and secrete factors that promote atherosclerotic plaque vulnerability and disease. Here, we report increased levels and activity of dipeptidyl pep
Externí odkaz:
https://doaj.org/article/097cd3f88b2846ebbe4f877f1734a991
Autor:
Alberto Diaz-Ruiz, Tyler Rhinesmith, Laura C. D. Pomatto-Watson, Nathan L. Price, Farzin Eshaghi, Margaux R. Ehrlich, Jacqueline M. Moats, Melissa Carpenter, Annamaria Rudderow, Sebastian Brandhorst, Julie A. Mattison, Miguel A. Aon, Michel Bernier, Valter D. Longo, Rafael de Cabo
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Understanding the contribution of diet composition, calories and length of fasting in health maintenance is still challenging. Here the authors compare the effects of cycles of intermittent very low calorie intake achieved with a plant-based fasting
Externí odkaz:
https://doaj.org/article/1dc4b15f57244a44ad6c5f3abdb932b9
Autor:
Edith M. Walker, Nadia Slisarenko, Giovanni L. Gerrets, Brooke F. Grasperge, Julie A. Mattison, Patricia J. Kissinger, David A. Welsh, Ronald S. Veazey, S. Michal Jazwinski, Namita Rout
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
HIV-associated inflammation has been implicated in the premature aging and increased risk of age-associated comorbidities in cART-treated individuals. However, the immune mechanisms underlying the chronic inflammatory state of cART-suppressed HIV inf
Externí odkaz:
https://doaj.org/article/8aba6d9685894ef3b21450265522b667
Autor:
Evi M. Mercken, Miriam Capri, Bethany A. Carboneau, Maria Conte, Juliana Heidler, Aurelia Santoro, Alejandro Martin-Montalvo, Marta Gonzalez-Freire, Husam Khraiwesh, José A. González-Reyes, Ruin Moaddel, Yongqing Zhang, Kevin G. Becker, José M. Villalba, Julie A. Mattison, Ilka Wittig, Claudio Franceschi, Rafael de Cabo
Publikováno v:
npj Aging and Mechanisms of Disease, Vol 3, Iss 1, Pp 1-22 (2017)
Conserved and unique aging regulatory pathways Aging is a complex phenomenon involving functional declines in multiple physiological systems with the passage of time. Focusing on skeletal muscle, a group of international scientists identified pathway
Externí odkaz:
https://doaj.org/article/7226c7ed427e4ac3ac7634971f4fca38
Autor:
Julie A. Mattison, Ricki J. Colman, T. Mark Beasley, David B. Allison, Joseph W. Kemnitz, George S. Roth, Donald K. Ingram, Richard Weindruch, Rafael de Cabo, Rozalyn M. Anderson
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Caloric restriction (CR) delays ageing of model organisms, but whether it works in nonhuman primates has been controversial. Here, the authors pool and reanalyse data from two long-running CR primate studies, concluding that moderate CR indeed improv
Externí odkaz:
https://doaj.org/article/3a76c66b68f7460284eef313ff046d21
Autor:
Mereena George Ushakumary, Mingyi Wang, Harikrishnan V, Allen Sam Titus, Jing Zhang, Lijuan Liu, Robert Monticone, Yushi Wang, Julie A Mattison, Rafael de Cabo, Edward G Lakatta, Shivakumar Kailasam
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0225911 (2019)
Collagen accumulation and remodeling in the vascular wall is a cardinal feature of vascular fibrosis that exacerbates the complications of hypertension, aging, diabetes and atherosclerosis. With no specific therapy available to date, identification o
Externí odkaz:
https://doaj.org/article/01c27aa1a8eb4f21b1fb4431cd1bfc70
Autor:
Michael B. Stout, Kelli L. Vaughan, Jose V. V. Isola, Shivani N. Mann, Bayli Wellman, Jessica M. Hoffman, Hunter L. Porter, Willard M. Freeman, Julie A. Mattison
Publikováno v:
GeroScience.