Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Julie, Van der Zee"'
Autor:
Amber Nous, Laura Seynaeve, Odile Feys, Vincent Wens, Xavier De Tiège, Pieter Van Mierlo, Amir G. Baroumand, Koenraad Nieboer, Gert-Jan Allemeersch, Shana Mangelschots, Veronique Michiels, Julie van der Zee, Christine Van Broeckhoven, Annemie Ribbens, Ruben Houbrechts, Sara De Witte, Mandy Melissa Jane Wittens, Maria Bjerke, Caroline Vanlersberghe, Sarah Ceyssens, Guy Nagels, Ilse Smolders, Sebastiaan Engelborghs
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-20 (2024)
Abstract Background Epileptic seizures are an established comorbidity of Alzheimer’s disease (AD). Subclinical epileptiform activity (SEA) as detected by 24-h electroencephalography (EEG) or magneto-encephalography (MEG) has been reported in tempor
Externí odkaz:
https://doaj.org/article/916fefda8641476cb9b404413c08dfdd
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-13 (2021)
Abstract Knowledge of the molecular etiology of neurodegenerative brain diseases (NBD) has substantially increased over the past three decades. Early genetic studies of NBD families identified rare and highly penetrant deleterious mutations in causal
Externí odkaz:
https://doaj.org/article/f86322bba726436f994db3a10d32e2f0
Autor:
Federica Perrone, Maria Bjerke, Elisabeth Hens, Anne Sieben, Maarten Timmers, Arne De Roeck, Rik Vandenberghe, Kristel Sleegers, Jean-Jacques Martin, Peter P. De Deyn, Sebastiaan Engelborghs, Julie van der Zee, Christine Van Broeckhoven, Rita Cacace, on behalf of the BELNEU Consortium
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-14 (2020)
Abstract Background Alzheimer’s disease (AD) mutations in amyloid precursor protein (APP) and presenilins (PSENs) could potentially lead to the production of longer amyloidogenic Aβ peptides. Amongst these, Aβ1–43 is more prone to aggregation a
Externí odkaz:
https://doaj.org/article/3a66eaa6876e44d293dc52f63c72776e
Autor:
Julie van der Zee, Lubina Dillen, Yalda Baradaran-Heravi, Helena Gossye, Cemile Koçoğlu, Ivy Cuyt, Bart Dermaut, Anne Sieben, Jonathan Baets, Peter De Jonghe, Rik Vandenberghe, Peter De Deyn, Patrick Cras, Sebastiaan Engelborghs, Christine Van Broeckhoven
Publikováno v:
Neurobiology of Disease, Vol 156, Iss , Pp 105421- (2021)
Neurodegenerative disorders like frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) are pathologically characterized by toxic protein deposition in the cytoplasm or nucleus of affected neurons and glial cells. Many of these aggrega
Externí odkaz:
https://doaj.org/article/389849129c364995bb8525525012f8c3
Autor:
Eva Parobkova, Julie van der Zee, Lubina Dillen, Christine Van Broeckhoven, Robert Rusina, Radoslav Matej
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Background: Sporadic Creutzfeldt–Jakob disease (sCJD) is the most common type of a group of transmissible spongiform encephalopathies (prion diseases). The etiology of the sporadic form of CJD is still unclear. sCJD can occur in combination with ot
Externí odkaz:
https://doaj.org/article/b4da639e49a44ee7af41495611c96585
Publikováno v:
Neurobiology of Disease, Vol 134, Iss , Pp - (2020)
Stress granules (SGs) are dynamic membraneless compartments composed out of RNA-binding proteins (RBPs) and RNA molecules that assemble temporarily to allow the cell to cope with cellular stress by stalling mRNA translation and moving synthesis towar
Externí odkaz:
https://doaj.org/article/627295467aad4f06ba90abcf04d1a07f
Autor:
Evelien Van Schoor, Mathieu Vandenbulcke, Valérie Bercier, Rik Vandenberghe, Julie van der Zee, Christine Van Broeckhoven, Markus Otto, Bernard Hanseeuw, Philip Van Damme, Ludo Van Den Bosch, Dietmar Rudolf Thal
Publikováno v:
Biomolecules, Vol 12, Iss 3, p 440 (2022)
Recently, disease-associated variants of the TUBA4A gene were identified in patients with amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Here, we present the neuropathological report of a patient with the semantic variant of p
Externí odkaz:
https://doaj.org/article/6e8cc74ee70d4da59f43565a0af55515
Autor:
Carina Lehmer, Martin H Schludi, Linnea Ransom, Johanna Greiling, Michaela Junghänel, Nicole Exner, Henrick Riemenschneider, Julie van der Zee, Christine Van Broeckhoven, Patrick Weydt, Michael T Heneka, Dieter Edbauer
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 6, Pp 1-14 (2018)
Abstract CHCHD10 mutations are linked to amyotrophic lateral sclerosis, but their mode of action is unclear. In a 29‐year‐old patient with rapid disease progression, we discovered a novel mutation (Q108P) in a conserved residue within the coiled
Externí odkaz:
https://doaj.org/article/e5c50d6c5b4645e99a546abfbbb506e9
Autor:
Joery Goossens, Maria Bjerke, Sara Van Mossevelde, Tobi Van den Bossche, Johan Goeman, Bart De Vil, Anne Sieben, Jean-Jacques Martin, Patrick Cras, Peter Paul De Deyn, Christine Van Broeckhoven, Julie van der Zee, Sebastiaan Engelborghs
Publikováno v:
Alzheimer’s Research & Therapy, Vol 10, Iss 1, Pp 1-10 (2018)
Abstract Background We explored the diagnostic performance of cerebrospinal fluid (CSF) biomarkers in allowing differentiation between frontotemporal lobar degeneration (FTLD) and Alzheimer’s disease (AD), as well as between FTLD pathological subty
Externí odkaz:
https://doaj.org/article/f8f4e71637f14a918acbcd4e30b0dd02
Autor:
Anne Sieben, Sara Van Mossevelde, Eline Wauters, Sebastiaan Engelborghs, Julie van der Zee, Tim Van Langenhove, Patrick Santens, Marleen Praet, Paul Boon, Marijke Miatton, Sofie Van Hoecke, Mathieu Vandenbulcke, Rik Vandenberghe, Patrick Cras, Marc Cruts, Peter Paul De Deyn, Christine Van Broeckhoven, Jean-Jacques Martin
Publikováno v:
Alzheimer’s Research & Therapy, Vol 10, Iss 1, Pp 1-13 (2018)
Abstract Background In this paper, we describe the clinical and neuropathological findings of nine members of the Belgian progranulin gene (GRN) founder family. In this family, the loss-of-function mutation IVS1 + 5G > C was identified in 2006. In 20
Externí odkaz:
https://doaj.org/article/62394803736045fe8e421489ba4a07da