Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Julie, Sanderson"'
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/4cbb502678254375bf9737829130c935
Autor:
Andrew Osborne, Amal Aldarwesh, Jeremy D Rhodes, David C Broadway, Claire Everitt, Julie Sanderson
Publikováno v:
PLoS ONE, Vol 10, Iss 1, p e0115591 (2015)
PURPOSE:Elevated intraocular pressure (IOP) is a major risk factor for glaucoma. One consequence of raised IOP is that ocular tissues are subjected to increased hydrostatic pressure (HP). The effect of raised HP on stress pathway signaling and retina
Externí odkaz:
https://doaj.org/article/16c9574f65c14bccac1c6c157c806ef6
Publikováno v:
Archives of toxicology. 93(3)
Cyclin-dependent kinases (CDKs) are a family of kinases associated predominantly with cell cycle control, making CDK inhibitors interesting candidates for anti-cancer therapeutics. However, retinal toxicity (loss of photoreceptors) has been associate
Publikováno v:
Stem Cells (Dayton, Ohio)
Optic neuropathies such as glaucoma occur when retinal ganglion cells (RGCs) in the eye are injured. Strong evidence suggests mesenchymal stem cells (MSCs) could be a potential therapy to protect RGCs; however, little is known regarding their effect
Publikováno v:
British Journal of Ophthalmology. 95:720-726
Aims To develop human organotypic retinal cultures (HORCs) to study retinal ganglion cell (RGC) death in response to ischaemic and excitotoxic insults, both known to cause loss of RGCs and proposed as mechanisms involved in glaucomatous retinal neuro
Publikováno v:
Experimental Eye Research. 89:995-1002
Quercetin is a dietary bioflavonoid which has been shown to inhibit lens opacification in a number of models of cataract. The objectives of this study were to determine gene expression changes in human lens epithelial cells in response to quercetin a
Autor:
Jeremy D. Rhodes, Julie Sanderson
Publikováno v:
Experimental Eye Research. 88:226-234
Excessive Ca(2+) can be detrimental to cells and raised levels of Ca(2+) in human lenses with cortical cataract have been found to play a major role in the opacification process. Ca(2+) homeostasis is therefore, recognised as having fundamental impor
Publikováno v:
Experimental eye research. 143
There is a growing need for models of human diseases that utilise native, donated human tissue in order to model disease processes and develop novel therapeutic strategies. In this paper we assessed the suitability of adult human retinal explants as
Publikováno v:
Aquaculture Nutrition. 11:321-332
This study was conducted to investigate protein synthesis rates and metabolism of histidine (His)-derivatives in lenses of Atlantic salmon (Salmo salar L.) of different dietary His background during parr–smolt transformation. Two populations of Atl
Publikováno v:
The Joint Commission Journal on Quality Improvement. 22:492-504
Article-at-a-Glance Background Using standardized measures, American Group Practice Association care providers compiled a national database from which patients could be tracked, allowing for epidemiologic comparisons among treatments, sources of care