Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Julie, Hang"'
Autor:
Nicholas J. Agard, Gu Zhang, John Ridgeway, Danielle M. Dicara, Phillip Y. Chu, Rachana Ohri, Sarah Sanowar, Jean-Michel Vernes, Hannah Chi, Jiameng Zhang, Emily Holz, Maciej Paluch, Guannan He, Yingjia Benson, Jianhuan Zhang, Pamela Chan, Nga Tang, Prachi Javale, Blair Wilson, Kathy Barrett, Rebecca K. Rowntree, Julie Hang, Y. Gloria Meng, Phil Hass, Germaine Fuh, Robert Piskol, Vladimir Bantseev, Kelly M. Loyet, John C. Tran, Cong Wu, Vahan B. Indjeian, Vittal Shivva, Minhong Yan
Publikováno v:
Translational vision sciencetechnology. 11(10)
Diabetic macular edema (DME) is the leading cause of vision loss and blindness among working-age adults. Although current intravitreal anti-vascular endothelial growth factor (VEGF) therapies improve vision for many patients with DME, approximately h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4de973b297d39ff4f6a06b6bb5da9129
https://pubmed.ncbi.nlm.nih.gov/36255358
https://pubmed.ncbi.nlm.nih.gov/36255358
Autor:
Julie Hang, Yan Wu, Wei-Ching Liang, Kenneth J. Katschke, Paul Moran, Charles Eigenbrot, Michael T. Lipari, Mike Elliott, Daniel Kirchhofer, Scott Stawicki, Alberto Estevez, Menno van Lookeren Campagne, Claudio Ciferri
Publikováno v:
Biochemical Journal. 472:169-181
High temperature requirement A1 (HtrA1) is a trypsin-fold serine protease implicated in the progression of age-related macular degeneration (AMD). Our interest in an antibody therapy to neutralize HtrA1 faces the complication that the target adopts a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baf026b19620b570de1a6f49b91956d4
https://doi.org/10.1042/bj20150601
https://doi.org/10.1042/bj20150601
Autor:
Toni Kline, Sihong Zhou, Jeffrey A. Hanson, Mary Rose Masikat, Venita I. De Almeida, Ryan Stafford, Maureen Fitch Bruhns, Cristina Abrahams, Gang Yin, Willy A. Solis, Krishna Bajjuri, Alexander Steiner, Adam Galan, Xiaofan Li, Cuong D. Tran, Stellanie Krimm, Alice Yam, Abigail Yu, Trevor J. Hallam, Mark Lupher, Robert Henningsen, Julie Hang, Tyler H. Heibeck, Dharti Kothari, James Zawada
Publikováno v:
Clinical Cancer Research. 25:NT-090
OBJECTIVES: Folate receptor alpha (FolRα) is a cell-surface glycoprotein, highly expressed in ovarian and endometrial adenocarcinoma, and thus a promising target for cancer therapy using antibody drug conjugates (ADCs). Most ADCs currently in develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::acaa1d4bcef805a7b50ae79f4eceb2c5
https://doi.org/10.1158/1557-3265.ovcasymp18-nt-090
https://doi.org/10.1158/1557-3265.ovcasymp18-nt-090
Autor:
Meera Ramanujam, Daigen Xu, Soo Min, John Woods, Jennifer Postelnek, Julia Ayala, Kai-Yeung Lau, Holly Hilton, Julie Hang, Yong Kim, Julie DeMartino, Rosario Garrido, Mario Giron, Stella Stefanova, Satwant K. Narula, Nena Dimaano, Toni Whittard, Natalie D. Keirstead, Alka Patel, Jacob LaStant, Paola Mina-Osorio
Publikováno v:
Arthritis & Rheumatism. 65:2380-2391
Objective Bruton's tyrosine kinase (BTK) plays a critical role in B cell development and function. We recently described a selective BTK inhibitor, RN486, that blocks B cell receptor (BCR) and Fcγ receptor signaling and is efficacious in animal mode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7760a9350ae5f85d11e0eaa60f43845
https://doi.org/10.1002/art.38047
https://doi.org/10.1002/art.38047
Autor:
Paola, Mina-Osorio, Jacob, LaStant, Natalie, Keirstead, Toni, Whittard, Julia, Ayala, Stella, Stefanova, Rosario, Garrido, Nena, Dimaano, Holly, Hilton, Mario, Giron, Kai-Yeung, Lau, Julie, Hang, Jennifer, Postelnek, Yong, Kim, Soo, Min, Alka, Patel, John, Woods, Meera, Ramanujam, Julie, DeMartino, Satwant, Narula, Daigen, Xu
Publikováno v:
Arthritis and rheumatism. 65(9)
Bruton's tyrosine kinase (BTK) plays a critical role in B cell development and function. We recently described a selective BTK inhibitor, RN486, that blocks B cell receptor (BCR) and Fcγ receptor signaling and is efficacious in animal models of arth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e744b7da2509d6cb630c54cd7da30c93
https://pubmed.ncbi.nlm.nih.gov/23754328
https://pubmed.ncbi.nlm.nih.gov/23754328
Autor:
I. Najera, Sophie Le Pogam, Graham Maile, Hobbs Christopher John, JH Merrett, Steven Swallow, Carl Laxton, Julie Hang, Rene Devos, Stewart J. Baker, Han Ma, Keshab Sarma, Julian Symons, Klaus Klumpp, David Bernard Smith, Vincent Leveque, David R. Vesey, Peter Blomgren, Mark D. Smith, Arkadius Pichota, Joseph Armstrong Martin, W.R. Jiang, Caroline Granycome, Nick Cammack
Publikováno v:
Bioorganicmedicinal chemistry letters. 17(9)
A series of 4'-substituted ribonucleoside derivatives has been prepared and evaluated for inhibition of hepatitis C virus (HCV) RNA replication in cell culture. The most potent and non-cytotoxic derivative was compound 28 (4'-azidocytidine, R1479) wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75a5e8af068b7cffce86f83a0bd1b0c8
https://pubmed.ncbi.nlm.nih.gov/17317178
https://pubmed.ncbi.nlm.nih.gov/17317178
Autor:
Brian Higgins, Markus Thomas, Annette Seidl, Chandra Pamulapati, Alvin S. Stern, Packman Kathryn E, Silke Hansen, Ying Li, Huifeng Niu, Kuo-Sen Huang, David C. Heimbrook, Windy Berkofsky-Fessler, Sherif Daouti, Julie Hang, Olaf Mundigl, Debra Lucas-McGady, James Cai, Zoran Filipovic, Xiaolei Zhang, Holly Hilton, Ueli Gubler, Gennady Samokhin, Christine Tardell
Publikováno v:
Cancer Research. 72:4827-4827
Hepsin is overexpressed in prostate and other cancers where it is implicated in promoting tumor growth, invasion, and metastasis. To further our understanding of the role of hepsin in prostate and breast cancer, a fully humanized monoclonal antibody
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8e59ea379adae5b7c2418c979b290ca
https://doi.org/10.1158/1538-7445.am2012-4827
https://doi.org/10.1158/1538-7445.am2012-4827
Autor:
George Stepan, Marie Dinh, Yanli Yang, Junjun Gao, Julie Hang, Klaus Klumpp, Vincent Leveque, Mohammad Hekmat-Nejad, Phil Kobel
Publikováno v:
Antiviral Research. 86:A20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff3dd2ab379dcad3a9f2209d5e088452
https://doi.org/10.1016/j.antiviral.2010.02.335
https://doi.org/10.1016/j.antiviral.2010.02.335
The trimeric serine protease HtrA1 forms a cage-like inhibition complex with an anti-HtrA1 antibody.
Autor:
Ciferri, Claudio, Lipari, Michael T., Wei-Ching Liang, Estevez, Alberto, Julie Hang, Stawicki, Scott, Yan Wu, Moran, Paul, Elliott, Mike, Eigenbrot, Charles, Katschke, Kenneth J., van Lookeren Campagne, Menno, Kirchhofer, Daniel
Publikováno v:
Biochemical Journal; 12/1/2015, Vol. 472 Issue 2, p169-181, 13p
Autor:
Yanli Yang, Klaus Klumpp, George Stepan, Tony Giannetti, Vincent Leveque, Julie Hang, Nick Cammack
Publikováno v:
Antiviral Research. 78:A23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::685fc9db231c1f67b9de7d8c6d6fa79a
https://doi.org/10.1016/j.antiviral.2008.01.033
https://doi.org/10.1016/j.antiviral.2008.01.033