Výsledky vyhledávání - "Juliano V, Alves"

Akademický článek

Progranulin Maintains Blood Pressure and Vascular Tone Dependent on EphrinA2 and Sortilin1 Receptors and Endothelial Nitric Oxide Synthase Activation

Autor: Ariane Bruder‐Nascimento, Wanessa M. C. Awata, Juliano V. Alves, Shubhnita Singh, Rafael M. Costa, Thiago Bruder‐Nascimento

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 16 (2023)

Background The mechanisms determining vascular tone are still not completely understood, even though it is a significant factor in blood pressure management. Many circulating proteins have a significant impact on controlling vascular tone. Progranuli

Externí odkaz: https://doaj.org/article/61fe38af89ee4c318acc18d47bbc9c59

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Akademický článek

Testosterone Contributes to Vascular Dysfunction in Young Mice Fed a High Fat Diet by Promoting Nuclear Factor E2–Related Factor 2 Downregulation and Oxidative Stress

Autor: Rafael M. Costa, Rhéure Alves-Lopes, Juliano V. Alves, Carolina P. Servian, Fabíola L. Mestriner, Fernando S. Carneiro, Núbia de S. Lobato, Rita C. Tostes

Publikováno v: Frontiers in Physiology, Vol 13 (2022)

Obesity, an important risk factor for cardiovascular disease, promotes vascular oxidative stress. Considering that free testosterone levels remain within the reference range, especially in obese young men and that testosterone stimulates reactive oxy

Externí odkaz: https://doaj.org/article/f8ce664d69e642a3be3a45f518547715

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Inhibition of IL-6 signaling prevents serum-induced umbilical cord artery dysfunction from patients with severe COVID-19

Autor: Cellyne R. Almeida, Júlia F. Lima, Mirele R. Machado, Juliano V. Alves, Ariel E.S. Couto, Ligia C.B. Campos, Carolina D. Avila-Mesquita, Maria Auxiliadora-Martins, Christiane Becari, Paulo Louzada-Júnior, Rita C. Tostes, Núbia S. Lobato, Rafael M. Costa

Publikováno v: American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 324:R435-R445

Coronavirus disease 2019 (COVID-19) infection has a negative impact on the cytokine profile of pregnant women. Increased levels of proinflammatory cytokines seem to be correlated with the severity of the disease, in addition to predisposing to miscar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b487e9178546cc4b01988cc39d38677d
https://doi.org/10.1152/ajpregu.00154.2022

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Akademický článek

Nrf2 as a Potential Mediator of Cardiovascular Risk in Metabolic Diseases

Autor: Rafael M. da Costa, Daniel Rodrigues, Camila A. Pereira, Josiane F. Silva, Juliano V. Alves, Núbia S. Lobato, Rita C. Tostes

Publikováno v: Frontiers in Pharmacology, Vol 10 (2019)

Free radicals act as secondary messengers, modulating a number of important biological processes, including gene expression, ion mobilization in transport systems, protein interactions and enzymatic functions, cell growth, cell cycle, redox homeostas

Externí odkaz: https://doaj.org/article/53d2b511e9a841f4a52d565ea798fa74

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Suppressed vascular Rho-kinase activation is a protective cardiovascular mechanism in obese female mice

Autor: Gabriela Souza Barbosa, Rafael M Costa, Wanessa MC Awata, Shubhnita Singh, Juliano V Alves, Ariane Bruder-Nascimento, Camila Renata Corrêa, Thiago Bruder-Nascimento

BackgroundObesity is the number one cardiovascular risk factor for both men and women and is a complex condition. Although a sex dimorphism on vascular function has already been noted, the underlying processes remain unclear. The Rho-kinase pathway h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::95ba588c0ca9ea4d37971b8a4ae49e54
https://doi.org/10.1101/2023.04.12.536489

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Progranulin maintains blood pressure and vascular tone dependent on EphrinA2 and Sortilin1 receptors and eNOS activation

Autor: Ariane Bruder-Nascimento, Wanessa M.C. Awata, Juliano V. Alves, Shubhnita Singh, Rafael M. Costa, Thiago Bruder-Nascimento

Background:Even though vascular tone is an important determinant of blood pressure management, the processes governing it are still not completely understood. Many circulating proteins have a significant impact on controlling vascular tone. Progranul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6759c6a3149bea848f5b3642f300318b
https://doi.org/10.1101/2023.04.02.534563

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Akademický článek

Increased O-GlcNAcylation of Endothelial Nitric Oxide Synthase Compromises the Anti-contractile Properties of Perivascular Adipose Tissue in Metabolic Syndrome

Autor: Rafael M. da Costa, Josiane F. da Silva, Juliano V. Alves, Thiago B. Dias, Diane M. Rassi, Luis V. Garcia, Núbia de Souza Lobato, Rita C. Tostes

Publikováno v: Frontiers in Physiology, Vol 9 (2018)

Under physiological conditions, the perivascular adipose tissue (PVAT) negatively modulates vascular contractility. This property is lost in experimental and human obesity and in the metabolic syndrome, indicating that changes in PVAT function may co

Externí odkaz: https://doaj.org/article/39fbdef97b104c07b30ed25297c36094

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