A Model of Chronic Exposure to Unpredictable Mild Socio-Environmental Stressors Replicates Some Spaceflight-Induced Immunological Changes

Autor: Fanny Gaignier, Christine Legrand-Frossi, Emilien Stragier, Julianne Mathiot, Jean-Louis Merlin, Charles Cohen-Salmon, Laurence Lanfumey, Jean-Pol Frippiat

Publikováno v: Frontiers in Physiology, Vol 9 (2018)

During spaceflight, astronauts face radiations, mechanical, and socio-environmental stressors. To determine the impact of chronic socio-environmental stressors on immunity, we exposed adult male mice to chronic unpredictable mild psychosocial and env

Externí odkaz: https://doaj.org/article/48d3a2c10f114ece94eb52e72dcfac51

Activation of T cells by dendritic cells exposed to a reference sensitizer Towards a promising model to assess the allergenic potential of chemicals

Autor: Fabrice Battais, Isabelle Sponne, Isabelle Langonné, F. Gagnaire, Christophe Paris, Julianne Mathiot, Hakima Abdessadeq, Samuel Muller, Cécile Huppert

Publikováno v: Contact Dermatitis
Contact Dermatitis, Wiley, 2018, 79 (2), pp.67-75. ⟨10.1111/cod.12991⟩
Contact Dermatitis, 2018, 79 (2), pp.67-75. ⟨10.1111/cod.12991⟩

International audience; Background - Low molecular weight chemicals constitute one of the major causes of occupational allergies. European legislation on chemicals recommends limiting the use of in vivo models for assessing the sensitizing potential

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c23d65fb194d3c6a59a8d7ee9ec56327
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01795806

Activation of T cells by dendritic cells exposed to a reference sensitizer: Towards a promising model to assess the allergenic potential of chemicals.

Autor: Huppert, Cécile^1,2, Paris, Christophe^2,3, Langonné, Isabelle¹, Muller, Samuel¹, Mathiot, Julianne¹, Abdessadeq, Hakima¹, Gagnaire, François¹, Battais, Fabrice¹, Sponne, Isabelle¹ isabelle.sponne@inrs.fr

Publikováno v: Contact Dermatitis (01051873). Aug2018, Vol. 79 Issue 2, p67-75. 9p.