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pro vyhledávání: '"Julianne A. Lombardo"'
Autor:
Julianne A. Lombardo, Edward A. Stern, Bradley T. Hyman, Brian J. Bacskai, Frank J. Attenello, Gregory A. Hickey
Publikováno v:
The Journal of Neuroscience. 24:4535-4540
The accumulation of amyloid-β protein into plaques is a characteristic feature of Alzheimer's disease. However, the contribution of amyloid-β plaques to neuronal dysfunction is unknown. We compared intracellular recordings from neocortical pyramida
Autor:
Bradley T. Hyman, Gregory A. Hickey, Julianne A. Lombardo, Edward A. Stern, Megan E. McLellan, Stephen T. Kajdasz, Brian J. Bacskai
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 23(34)
The accumulation of amyloid-β into insoluble plaques is a characteristic feature of Alzheimer's disease. Neuronal morphology is distorted by plaques: rather than being essentially straight, they are substantially more curved than those in control ti