Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Julianna M. Wright"'
Publikováno v:
STAR Protocols, Vol 1, Iss 3, Pp 100138- (2020)
Summary: Alternative splicing greatly expands the coding capacity of the human genome, but how many alternative transcripts are translated as proteins or carry functional importance remains unknown and awaits experimental verification. Here, we descr
Externí odkaz:
https://doaj.org/article/f90e896b07654cefa87a0e15a0d6f6f2
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 323:H538-H558
The risks of heart diseases are significantly modulated by age and sex, but how these factors influence baseline cardiac gene expression remains incompletely understood. Here, we used RNA sequencing and mass spectrometry to compare gene expression in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d9e54685173a854f7bd369c1fad4546
https://doi.org/10.1152/ajpheart.00244.2022
https://doi.org/10.1152/ajpheart.00244.2022
Computation-assisted targeted proteomics of alternative splicing protein isoforms in the human heart
Publikováno v:
J Mol Cell Cardiol
Alternative splicing is prevalent in the heart and implicated in many cardiovascular diseases, but not every alternative transcript is translated and detecting non-canonical isoforms at the protein level remains challenging. Here we show the use of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f82435785652d898c565e58cd748416
https://doi.org/10.1016/j.yjmcc.2021.01.007
https://doi.org/10.1016/j.yjmcc.2021.01.007