Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Julianna C. King"'
Autor:
Xiuxiu Lu, Venkata R. Sabbasani, Vasty Osei-Amponsa, Christine N. Evans, Julianna C. King, Sergey G. Tarasov, Marzena Dyba, Sudipto Das, King C. Chan, Charles D. Schwieters, Sulbha Choudhari, Caroline Fromont, Yongmei Zhao, Bao Tran, Xiang Chen, Hiroshi Matsuo, Thorkell Andresson, Raj Chari, Rolf E. Swenson, Nadya I. Tarasova, Kylie J. Walters
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Rpn13 is a substrate receptor of the 26S proteasome and an anti-cancer drug target. Here, the authors identify and characterize XL5, a lead compound that binds to the N-terminal Pru domain of human Rpn13 (hRpn13), solve the NMR structure of XL5-ligat
Externí odkaz:
https://doaj.org/article/08204c7dee354ca7ab5e0c3b7e0c28d6
Autor:
Emily A. Dangelmaier, Xiao Ling Li, Corrine Corrina R. Hartford, Julianna C. King, Meira S. Zibitt, Raj Chari, Ioannis Grammatikakis, Ashish Lal
Publikováno v:
Mol Cell Biol
One of the primary mechanisms of post-transcriptional gene regulation is the modulation of RNA stability. We recently discovered that LINC00675, a transcript annotated as a long noncoding RNA (lncRNA), is transcriptionally regulated by FOXA1 and enco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f6539f28ceeae7898930e8f948b4070
https://pubmed.ncbi.nlm.nih.gov/35274990
https://pubmed.ncbi.nlm.nih.gov/35274990
Autor:
Charles D. Schwieters, Xiuxiu Lu, Vasty Osei-Amponsa, Julianna C. King, Thorkell Andresson, Caroline Fromont, Rolf E. Swenson, Bao Tran, Xiang Chen, Kylie J. Walters, Yongmei Zhao, Nadya I. Tarasova, Hiroshi Matsuo, Marzena A. Dyba, Sulbha Choudhari, Raj Chari, Venkata R. Sabbasani, Sergey G. Tarasov, Christine N. Evans, King C. Chan
Proteasome substrate receptor hRpn13 is a promising anti-cancer target. By integrated in silico and biophysical screening, we identified a chemical scaffold that binds hRpn13 with non-covalent interactions that mimic the proteasome and a weak electro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb1579d6d5f0d3b01c43733af2d66184
https://doi.org/10.1101/2021.07.16.452547
https://doi.org/10.1101/2021.07.16.452547
