Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Juliane Wunderlich"'
Autor:
Juliane Wunderlich, Vadim Kotov, Lasse Votborg-Novél, Christina Ntalla, Maria Geffken, Sven Peine, Silvia Portugal, Jan Strauss
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Host iron deficiency is protective against severe malaria as the human malaria parasite Plasmodium falciparum depends on bioavailable iron from its host to proliferate. The essential pathways of iron acquisition, storage, export, and detoxification i
Externí odkaz:
https://doaj.org/article/41ca24f7995848168b06f53ee1542448
Autor:
Rency Mathew, Juliane Wunderlich, Karine Thivierge, Krystyna Cwiklinski, Claire Dumont, Leann Tilley, Petra Rohrbach, John P. Dalton
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract The Plasmodium falciparum M1 alanyl aminopeptidase and M17 leucyl aminopeptidase, PfM1AAP and PfM17LAP, are potential targets for novel anti-malarial drug development. Inhibitors of these aminopeptidases have been shown to kill malaria paras
Externí odkaz:
https://doaj.org/article/7f3e6597461544929c6fad7b3f979727
Autor:
Juliane Wunderlich
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Malaria remains a leading cause of death and disease in many tropical and subtropical regions of the world. Due to the alarming spread of resistance to almost all available antimalarial drugs, novel therapeutic strategies are urgently needed. As the
Externí odkaz:
https://doaj.org/article/cf0eeae0001443e6b9102e0e6b9be711
Autor:
Juliane Wunderlich, Marius Schmitt, Jessica Kimmel, Jan Stephan Wichers, Anna Bachmann, Dorothee Heincke, Tim W. Gilberger, Louisa Wilcke, Heidrun von Thien, Samuel Pazicky, Paul-Christian Burda, Sarah Scharf, Michael Filarsky, Christian Löw, Tobias Spielmann, Jan Strauss
Publikováno v:
Cellular microbiologyREFERENCES. 23(9)
The inner membrane complex (IMC) is a defining feature of apicomplexan parasites, which confers stability and shape to the cell, functions as a scaffolding compartment during the formation of daughter cells and plays an important role in motility and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::852f9f93db2a9b996a11cca09bf9bf50
https://pubmed.ncbi.nlm.nih.gov/33830607
https://pubmed.ncbi.nlm.nih.gov/33830607
Autor:
Krystyna Cwiklinski, Petra Rohrbach, Juliane Wunderlich, Leann Tilley, Karine Thivierge, John P. Dalton, Rency Mathew, Claire Dumont
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
The Plasmodium falciparum M1 alanyl aminopeptidase and M17 leucyl aminopeptidase, PfM1AAP and PfM17LAP, are potential targets for novel anti-malarial drug development. Inhibitors of these aminopeptidases have been shown to kill malaria parasites in c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2aa7675989b4add78d8fc03a27c8980
http://europepmc.org/articles/PMC7858622
http://europepmc.org/articles/PMC7858622
Autor:
Elias Georges, Sarah J. Reiling, Petra Rohrbach, Mara L. Leimanis, Juliane Wunderlich, Sonia Edaye
Publikováno v:
Molecular and Biochemical Parasitology. 195:34-42
Malaria is a major disease in the tropics where chemotherapy remains the main mode of treatment and as such the rise and spread of drug-resistant malaria can lead to human tragedy. Two membrane transport proteins, PfMDR1 (Plasmodium falciparum multid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d6e1d9cae8ddb00788efef163af3b23
https://doi.org/10.1016/j.molbiopara.2014.05.006
https://doi.org/10.1016/j.molbiopara.2014.05.006
Publikováno v:
Journal of Cellular and Molecular Medicine
Mutations in the multidrug resistance transporter of Plasmodium falciparum PfMDR1 have been implicated to play a significant role in the emergence of worldwide drug resistance, yet the molecular and biochemical mechanisms of this transporter are not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ce0bc7d64d25be638a53d2baa0255aa
http://europepmc.org/articles/PMC4196660
http://europepmc.org/articles/PMC4196660
Autor:
Juliane Wunderlich, Sarah J. Reiling, John P. Dalton, Corine G. Demanga, Jenny W.L. Eng, Petra Rohrbach
Publikováno v:
International Journal for Parasitology. 42:215-220
We describe methods for the large-scale in vitro culturing of synchronous and asynchronous blood-stage Plasmodium falciparum parasites in sterile disposable plastic bioreactors controlled by wave-induced motion (wave bioreactor). These cultures perfo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3724cf85755c4395f205387023d275d5
https://doi.org/10.1016/j.ijpara.2012.01.001
https://doi.org/10.1016/j.ijpara.2012.01.001
Publikováno v:
Frontiers in Bioscience. :1424-1448
During the development of malaria parasites within human erythrocytes, the fusion of digestive vesicles gives rise to a large digestive vacuole (DV). This organelle, which is maintained at low pH, processes 60-80 percent of the erythrocyte hemoglobin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1bf567bb2157ef5578dcd67d132e32f
https://doi.org/10.2741/s344
https://doi.org/10.2741/s344
Autor:
Wunderlich, Juliane, Kotov, Vadim, Votborg-Novél, Lasse, Ntalla, Christina, Geffken, Maria, Peine, Sven, Portugal, Silvia, Strauss, Jan
Publikováno v:
Frontiers in Cellular & Infection Microbiology; 2024, p1-26, 26p