Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Juliane Schroeder"'
Autor:
Juliane Schroeder, Kirsty Ross, Kathryn McIntosh, Shilan Jabber, Stuart Woods, Jenny Crowe, Janet Patterson Kane, James Alexander, Catherine Lawrence, Robin Plevin
Publikováno v:
RMD Open, Vol 5, Iss 1 (2019)
Objectives We have previously shown mitogen-activated protein kinase phosphatase 2 (MKP-2) to be a key regulator of proinflammatory cytokines in macrophages. In the study presented here, we investigated the role of MKP-2 in inflammatory arthritis wit
Externí odkaz:
https://doaj.org/article/af16d99b350249eca6ff4e9b3973b3d3
Autor:
Alan J. Hayes, Sanket Rane, Hannah E. Scales, Gavin R. Meehan, Robert A. Benson, Asher Maroof, Juliane Schroeder, Michio Tomura, Neil Gozzard, Andrew J. Yates, Paul Garside, James M. Brewer
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Initiation of adaptive immunity involves distinct migratory cell populations coming together in a highly dynamic and spatially organized process. However, we lack a detailed spatiotemporal map of these events due to our inability to track the fate of
Externí odkaz:
https://doaj.org/article/990e096a122f42f8ab6e7b00751d7cba
Autor:
Thikryat Neamatallah, Shilan Jabbar, Rothwelle Tate, Juliane Schroeder, Muhannad Shweash, James Alexander, Robin Plevin
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 14, p 3434 (2019)
Background: Mitogen-activated protein kinase phosphatase-2 (MKP-2) is a type 1 nuclear dual specific phosphatase (DUSP-4). It plays an important role in macrophage inflammatory responses through the negative regulation of Mitogen activated protein ki
Externí odkaz:
https://doaj.org/article/6d4cd45451e64d6fa0783547800d1c9b
Autor:
Stuart Woods, Juliane Schroeder, Helen A. McGachy, Robin Plevin, Craig W. Roberts, James Alexander
Publikováno v:
PLoS Pathogens, Vol 9, Iss 9 (2013)
Externí odkaz:
https://doaj.org/article/e305a2f8759d46e5a3b9a5c857c9bb2b
Autor:
Stuart Woods, Juliane Schroeder, Helen A McGachy, Robin Plevin, Craig W Roberts, James Alexander
Publikováno v:
PLoS Pathogens, Vol 9, Iss 8, p e1003535 (2013)
The dual specific phosphatase, MAP kinase phosphatase-2 (MKP-2) has recently been demonstrated to negatively regulate macrophage arginase-1 expression, while at the same time to positively regulate iNOS expression. Consequently, MKP-2 is likely to pl
Externí odkaz:
https://doaj.org/article/24e880428d8349f5a3197c0ce0bbafef
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 7, Iss 2, p e2064 (2013)
We have recently demonstrated that MAP kinase phosphatase 2 (MKP-2) deficient C57BL/6 mice, unlike their wild-type counterparts, are unable to control infection with the protozoan parasite Leishmania mexicana. Increased susceptibility was associated
Externí odkaz:
https://doaj.org/article/c28e91fdf12c4b88a267b26f2158b4db
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 5, Iss 12, p e1406 (2011)
Visceral leishmaniasis is a major neglected tropical disease, with an estimated 500,000 new cases and more than 50,000 deaths attributable to this disease every year. Drug therapy is available but costly and resistance against several drug classes ha
Externí odkaz:
https://doaj.org/article/8152d0dc9442416bb5c9b0750739fcde
Autor:
Mashael S Al-Mutairi, Laurence C Cadalbert, H Adrienne McGachy, Muhannad Shweash, Juliane Schroeder, Magdalena Kurnik, Callum M Sloss, Clare E Bryant, James Alexander, Robin Plevin
Publikováno v:
PLoS Pathogens, Vol 6, Iss 11, p e1001192 (2010)
In this study we generated a novel dual specific phosphatase 4 (DUSP4) deletion mouse using a targeted deletion strategy in order to examine the role of MAP kinase phosphatase-2 (MKP-2) in immune responses. Lipopolysaccharide (LPS) induced a rapid, t
Externí odkaz:
https://doaj.org/article/8b370344e4b845929912de640584ece4
Autor:
Neil Gozzard, Robert A. Benson, James M. Brewer, Andrew J. Yates, Sanket Rane, Juliane Schroeder, Paul Garside, Hannah E. Scales, Alan J. Hayes, Gavin R. Meehan, Michio Tomura, Asher Maroof
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Initiation of adaptive immunity involves distinct migratory cell populations coming together in a highly dynamic and spatially organized process. However, we lack a detailed spatiotemporal map of these events due to our inability to track the fate of
Autor:
James Alexander, Juliane Schroeder, Stuart Woods, Robin Plevin, Kirsty Ross, Janet Patterson Kane, Kathryn McIntosh, Jenny Crowe, Shilan Jabber, Catherine E. Lawrence
Publikováno v:
RMD Open
ObjectivesWe have previously shown mitogen-activated protein kinase phosphatase 2 (MKP-2) to be a key regulator of proinflammatory cytokines in macrophages. In the study presented here, we investigated the role of MKP-2 in inflammatory arthritis with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62ef31dae858eca3ad2457a32ba8db9c
https://eprints.gla.ac.uk/180248/1/180248.pdf
https://eprints.gla.ac.uk/180248/1/180248.pdf