Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Juliane Sarah Walz"'
1
Akademický článek
HLA Ligand Atlas: a benign reference of HLA-presented peptides to improve T-cell-based cancer immunotherapy
Autor: Jian Wang, Michael Weller, Roland Martin, Holger Moch, Julia Velz, Luca Regli, Hans-Georg Rammensee, Linus Backert, Oliver Kohlbacher, Ana Marcu, Leon Bichmann, Leon Kuchenbecker, Daniel Johannes Kowalewski, Lena Katharina Freudenmann, Lena Mühlenbruch, András Szolek, Maren Lübke, Philipp Wagner, Tobias Engler, Sabine Matovina, Mathias Hauri-Hohl, Konstantina Kapolou, Juliane Sarah Walz, Manuela Silginer, Markus W. Löffler, Florian Erhard, Andreas Schlosser, Stefan Stevanović, Marian Christoph Neidert
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 4 (2021)
Background The human leucocyte antigen (HLA) complex controls adaptive immunity by presenting defined fractions of the intracellular and extracellular protein content to immune cells. Understanding the benign HLA ligand repertoire is a prerequisite t
Externí odkaz: https://doaj.org/article/5f3fc47c106b4ae084c10a3498b6514a
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2
Akademický článek
Designing a SARS-CoV-2 T-Cell-Inducing Vaccine for High-Risk Patient Groups
Autor: Hans-Georg Rammensee, Cécile Gouttefangeas, Sonja Heidu, Reinhild Klein, Beate Preuß, Juliane Sarah Walz, Annika Nelde, Sebastian P. Haen, Michael Reth, Jianying Yang, Ghazaleh Tabatabai, Hans Bösmüller, Helen Hoffmann, Michael Schindler, Oliver Planz, Karl-Heinz Wiesmüller, Markus W. Löffler
Publikováno v: Vaccines, Vol 9, Iss 5, p 428 (2021)
We describe the results of two vaccinations of a self-experimenting healthy volunteer with SARS-CoV-2-derived peptides performed in March and April 2020, respectively. The first set of peptides contained eight peptides predicted to bind to the indivi
Externí odkaz: https://doaj.org/article/1fb9244aa47644348c0c213da3a5c238
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3
Akademický článek
HLA class I-restricted MYD88 L265P-derived peptides as specific targets for lymphoma immunotherapy
Autor: Annika Nelde, Juliane Sarah Walz, Daniel Johannes Kowalewski, Heiko Schuster, Olaf-Oliver Wolz, Janet Kerstin Peper, Yamel Cardona Gloria, Anton W. Langerak, Alice F. Muggen, Rainer Claus, Irina Bonzheim, Falko Fend, Helmut Rainer Salih, Lothar Kanz, Hans-Georg Rammensee, Stefan Stevanović, Alexander N. R. Weber
Publikováno v: OncoImmunology, Vol 6, Iss 3 (2017)
Genome sequencing has uncovered an array of recurring somatic mutations in different non-Hodgkin lymphoma (NHL) subtypes. If affecting protein-coding regions, such mutations may yield mutation-derived peptides that may be presented by HLA class I pro
Externí odkaz: https://doaj.org/article/6fbd23161b974b24849417e491c35159
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5
Abstract 3574: A Phase I trial of personalized multi-peptide vaccination in combination with the TLR1/2 ligand XS15 in CLL patients under Bruton-Tyrosin-Kinase-inhibitor based regimes - Preclinical development and study design
Autor: Maddalena Marconato, Annika Nelde, Yacine Maringer, Marcel Wacker, Marion Richter, Monika Denk, Helmut Salih, Jonas Heitmann, Juliane Sarah Walz
Publikováno v: Cancer Research. 82:3574-3574
Chronic lymphocytic leukemia (CLL) is the most common leukemia in adults. Despite the therapeutic success of novel small molecules (e.g. ibrutinib, idealisib and venetoclax), patients frequently experience disease relapse due to the persistence of mi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::447bdeaec4e4845e47990442b00c43a7
https://doi.org/10.1158/1538-7445.am2022-3574
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6
Correction to: Cancer testis antigen Cyclin A1 harbors several HLA‑A*02:01‑restricted T cell epitopes, which are presented and recognized in vivo
Autor: Anja Tatjana Teck, Sabrina Urban, Petra Quass, Annika Nelde, Heiko Schuster, Anne Letsch, Antonia Busse, Juliane Sarah Walz, Ulrich Keilholz, Sebastian Ochsenreither
Publikováno v: Cancer Immunology, Immunotherapy
Cyclin A1 is a promising antigen for T cell therapy being selectively expressed in high-grade ovarian cancer (OC) and acute myeloid leukemia (AML) stem cells. For adoptive T cell therapy, a single epitope has to be selected, with high affinity to MHC
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16293146beb45d8cc84345f27700a940
http://europepmc.org/articles/PMC8423697
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7
Correction to Supporting Information for Kowalewski et al., HLA ligandome analysis identifies the underlying specificities of spontaneous antileukemia immune responses in chronic lymphocytic leukemia (CLL)
Autor: Juliane Sarah Walz
The breakthrough development of clinically effective immune checkpoint inhibitors illustrates the potential of T-cell-based immunotherapy to effectively treat malignancies. A remaining challenge is to increase and guide the specificities of anticance
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1843ccb69d6cf214741509c4524d193
https://europepmc.org/articles/PMC4653161/
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