Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Juliane Hitzel"'
Autor:
Juliane Hitzel, Eunjee Lee, Yi Zhang, Sofia Iris Bibli, Xiaogang Li, Sven Zukunft, Beatrice Pflüger, Jiong Hu, Christoph Schürmann, Andrea Estefania Vasconez, James A. Oo, Adelheid Kratzer, Sandeep Kumar, Flávia Rezende, Ivana Josipovic, Dominique Thomas, Hector Giral, Yannick Schreiber, Gerd Geisslinger, Christian Fork, Xia Yang, Fragiska Sigala, Casey E. Romanoski, Jens Kroll, Hanjoong Jo, Ulf Landmesser, Aldons J. Lusis, Dmitry Namgaladze, Ingrid Fleming, Matthias S. Leisegang, Jun Zhu, Ralf P. Brandes
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-18 (2018)
During atherosclerosis, endothelial cells release purines in response to oxidized phospholipids. Here, Hitzel et al. show that oxidized phospholipids activate an MTHFD2-regulated gene network in endothelial cells which reprograms amino acid metabolis
Externí odkaz:
https://doaj.org/article/4401176dc9754aceb3a9a13dbd4a3e34
Autor:
Lunda Gu, Juliane Hitzel, Franziska Moll, Christoph Kruse, Randa Abdel Malik, Jens Preussner, Mario Looso, Matthias S Leisegang, Dieter Steinhilber, Ralf P Brandes, Christian Fork
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146645 (2016)
Epigenetic marks critically control gene expression and thus the cellular activity state. The functions of many epigenetic modifiers in the vascular system have not yet been studied. We screened for histone modifiers in endothelial cells and observed
Externí odkaz:
https://doaj.org/article/61fc4cc192fe4c20af5d77d442791cb2
Autor:
Matthias S. Leisegang, Wei Chen, Mario Looso, Eva C. Schwarz, Stefan Günther, Christian Fork, Juliane Hitzel, Ralf P. Brandes, Corina Ratiu, Jens Preussner, Andreas Weigert, Lunda Gu
Publikováno v:
FEBS Letters. 593:487-498
Histone3-lysine9 (H3K9) residues not only control gene expression, but also contribute to RNA splicing. Here, the H3K9 histone demethylase PHF8 was investigated in endothelial cells for its involvement in alternative splicing. An angiogenic sprouting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80b81d7b2142801e52a0c3e409591e40
https://doi.org/10.1002/1873-3468.13337
https://doi.org/10.1002/1873-3468.13337
Autor:
Elisabetta Gamen, Mario Looso, Ralf P. Brandes, Andrea E. Vasconez, Christian Fork, James A. Oo, Sandra Seredinski, Juliane Hitzel, Matthias S. Leisegang, Wei Chen, Ivana Josipovic, Beatrice Pflüger, Dagmar Meyer zu Heringdorf, Soni Savai Pullamsetti
Publikováno v:
Journal of molecular and cellular cardiology. 116
Sphingosine-1-Phosphate (S1P) is a potent signaling lipid. The effects of S1P are mediated by the five S1P receptors (S1PR). In the endothelium S1PR1 is the predominant receptor and thus S1PR1 abundance limits S1P signaling. Recently, lncRNAs were id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::109ccc3dbf7fa7c342deb329c4b8deea
https://pubmed.ncbi.nlm.nih.gov/29408197
https://pubmed.ncbi.nlm.nih.gov/29408197
Autor:
Ralf P. Brandes, Randa Abdel Malik, Jens Preussner, Lunda Gu, Christoph Kruse, Franziska Moll, Dieter Steinhilber, Mario Looso, Christian Fork, Matthias S. Leisegang, Juliane Hitzel
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 1, p e0146645 (2016)
PLoS ONE, Vol 11, Iss 1, p e0146645 (2016)
Epigenetic marks critically control gene expression and thus the cellular activity state. The functions of many epigenetic modifiers in the vascular system have not yet been studied. We screened for histone modifiers in endothelial cells and observed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5c66f2b251e01f6a3ebfcfada504716
https://publica.fraunhofer.de/handle/publica/257288
https://publica.fraunhofer.de/handle/publica/257288
Autor:
Juliane Hitzel, Kristian Helin, Yuliya Ponomareva, Sandra U. Schmitz, Lunda Gu, Christian Fork, Michael SzeKa Wong, Jiong Hu, Mareike Albert, Matthias S. Leisegang, Ralf P. Brandes, Ingrid Fleming, Shizuka Uchida, Ivana Josipovic, Dieter Steinhilber
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 35(7)
Objective— Altering endothelial biology through epigenetic modifiers is an attractive novel concept, which is, however, just in its beginnings. We therefore set out to identify chromatin modifiers important for endothelial gene expression and contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4c5334263c25099bc38309ff06c5d8b
https://pubmed.ncbi.nlm.nih.gov/26023081
https://pubmed.ncbi.nlm.nih.gov/26023081
Publikováno v:
Hypertension. 64
Objective: Endothelial cells are important elements in the vascular response to danger associated molecules signaling through Toll-like receptors (TLRs). Flotillin-1 and -2 are markers of membrane rafts but their true endothelial function is unknown.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5386119b19742429ae63c262207b7f68
https://doi.org/10.1161/hyp.64.suppl_1.444
https://doi.org/10.1161/hyp.64.suppl_1.444
Publikováno v:
Basic Research in Cardiology
Endothelial cells are important elements in the vascular response to danger-associated molecules signaling through toll-like receptors (TLRs). Flotillin-1 and -2 are markers of membrane rafts but their true endothelial function is unknown. We hypothe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90b3699568251eb762dba8a521d0c2d3