Study-based evaluation of the Abbott RealTime High Risk HPV test in comparison to the HC2 HR HPV test in women aged ≥30 years using residual LBC ThinPrep specimens

Autor: Thomas Iftner, Lisa Wang, Angelika Iftner, Barbara Holz, Juliane Haedicke-Jarboui, Nathalie Iftner, Reinhard von Wasielewski, Peter Martus, Gerd Boehmer

Publikováno v: BMC Infectious Diseases, Vol 16, Iss 1, Pp 1-9 (2016)

Abstract Background High-risk human papillomavirus (HR HPV) testing is already part of cervical cancer screening programs in a number of countries. New tests need to be validated not only in clinical studies but also in routine screening settings wit

Externí odkaz: https://doaj.org/article/4cf6af8385114989a41d145cf3c40eff

Longitudinal Clinical Performance of the RNA-Based Aptima Human Papillomavirus (AHPV) Assay in Comparison to the DNA-Based Hybrid Capture 2 HPV Test in Two Consecutive Screening Rounds with a 6-Year Interval in Germany

Autor: Alejandra Castanon, Sara Y. Brucker, Rebecca Landy, Claus Hann von Weyhern, Juliane Haedicke-Jarboui, Barbara Holz, Melanie Henes, Felix Neis, Thomas Iftner, Annette Staebler, Klaus-Joachim Neis, Peter Martus, Angelika Iftner, Diethelm Wallwiener, Astrid Woll-Herrmann, Peter Sasieni

Publikováno v: Iftner, T, Neis, K-J, Castanon, A, Landy, R, Holz, B, Woll-Herrmann, A, Iftner, A, Staebler, A, Wallwiener, D, von Weyhern, C H, Neis, F, Haedicke-Jarboui, J, Martus, P, Brucker, S, Henes, M & Sasieni, P 2019, ' Longitudinal Clinical Performance of the RNA-Based Aptima Human Papillomavirus (AHPV) Assay in Comparison to the DNA-Based Hybrid Capture 2 HPV Test in Two Consecutive Screening Rounds with a 6-Year Interval in Germany ', Journal of Clinical Microbiology, vol. 57, no. 1, e01177 . https://doi.org/10.1128/JCM.01177-18
Journal of Clinical Microbiology

Longitudinal data on the E6/E7 mRNA-based Aptima human papillomavirus (AHPV) assay exceeding three years in comparison to the gold standard Digene Hybrid Capture 2 (HC2) test are not available. We previously reported the cross-sectional data of the G

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32e4389dd71c2a3aa5feb02b0c479ca5
https://kclpure.kcl.ac.uk/ws/files/108890998/Journal_of_Clinical_Microbiology_2018_Iftner_JCM.01177_18.full.pdf

Brd4 inhibition suppresses HPV16 E6 expression and enhances chemoresponse: A potential new target in cervical cancer therapy

Autor: Olga, Rataj, Juliane, Haedicke-Jarboui, Frank, Stubenrauch, Thomas, Iftner

Publikováno v: International journal of cancer. 144(9)

Although a vast amount of research underlines the roles of the HR HPV E6 and E7 oncogenes in HPV-induced carcinogenesis of cervical cancer, it remains unclear whether these oncogenes are also involved in the resistance of the cancer against chemother

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::31d448cad706fd9ca2b3b930a83b3c2c
https://pubmed.ncbi.nlm.nih.gov/30421459

Human papillomaviruses and cancer

Autor: Thomas Iftner, Juliane Haedicke

Publikováno v: Radiotherapy and Oncology. 108:397-402

Human papillomaviruses (HPV) are small oncogenic DNA viruses of which more than 200 types have been identified to date. A small subset of these is etiologically linked to the development of anogenital malignancies such as cervical cancer. In addition

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05101d1e7eb0ebdc01bd7766a15cdc45
https://doi.org/10.1016/j.radonc.2013.06.004

The Ezrin-Radixin-Moesin Family Member Ezrin Regulates Stable Microtubule Formation and Retroviral Infection

Autor: Juliane Haedicke, Stephen P. Goff, Mojgan H. Naghavi, Kenia de los Santos

Publikováno v: Journal of Virology. 82:4665-4670

We recently identified the cytoskeletal regulatory protein moesin as a novel gene that inhibits retroviral replication prior to reverse transcription by downregulation of stable microtubule formation. Here, we provide evidence that overexpression of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50be32c90f51b4714af456acb7949507
https://doi.org/10.1128/jvi.02403-07