Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Juliane Gust"'
Autor:
Nicholas A. Vitanza, Rebecca Ronsley, Michelle Choe, Casey Henson, Mandy Breedt, Adriel Barrios-Anderson, Amy Wein, Christopher Brown, Adam Beebe, Ada Kong, Danielle Kirkey, Brittany M. Lee, Sarah E.S. Leary, Erin E. Crotty, Corrine Hoeppner, Susan Holtzclaw, Ashley L. Wilson, Joshua A. Gustafson, Jessica B. Foster, Jeffrey J. Iliff, Hannah E. Goldstein, Samuel R. Browd, Amy Lee, Jeffrey G. Ojemann, Navin Pinto, Juliane Gust, Rebecca A. Gardner, Michael C. Jensen, Jason S. Hauptman, Julie R. Park
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 36, Iss , Pp 100870- (2023)
Central nervous system (CNS) tumors are the most common solid malignancy in the pediatric population. Based on adoptive cellular therapy's clinical success against childhood leukemia and the preclinical efficacy against pediatric CNS tumors, chimeric
Externí odkaz:
https://doaj.org/article/0dd9cbf684b44b109bab4c85d507e99f
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Novel immunotherapies are increasingly being employed in pediatric oncology, both in the upfront and relapsed/refractory settings. Through various mechanisms of action, engagement and activation of the immune system can cause both generalized and dis
Externí odkaz:
https://doaj.org/article/39ab8e4b9c4442fdba2e85d9d25ac9e5
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Chimeric antigen receptor (CAR) T cells provide new therapeutic options for patients with relapsed/refractory hematologic malignancies. However, neurotoxicity is a frequent, and potentially fatal, complication. The spectrum of manifestations ranges f
Externí odkaz:
https://doaj.org/article/3129aaaa25034513ab0df1c94d4b574d
Autor:
Jasia Mahdi, Jorg Dietrich, Karin Straathof, Claire Roddie, Brian J. Scott, Tom Belle Davidson, Laura M. Prolo, Tracy T. Batchelor, Cynthia J. Campen, Kara L. Davis, Juliane Gust, Michael Lim, Robbie G. Majzner, Julie R. Park, Sonia Partap, Sneha Ramakrishna, Rebecca Richards, Liora Schultz, Nicholas A. Vitanza, Leo D. Wang, Crystal L. Mackall, Michelle Monje
Publikováno v:
Nature Medicine. 29:803-810
Autor:
Erin E. Crotty, Ashley L. Wilson, Tom Davidson, Sophia Tahiri, Juliane Gust, Andrea M. Griesinger, Sujatha Venkataraman, Julie R. Park, Sabine Mueller, Brian R. Rood, Eugene I. Hwang, Leo D. Wang, Nicholas A. Vitanza
Publikováno v:
Current Oncology Reports.
Purpose of Review Correlative studies should leverage clinical trial frameworks to conduct biospecimen analyses that provide insight into the bioactivity of the intervention and facilitate iteration toward future trials that further improve patient o
Autor:
Julie R. Park, Michael C. Jensen, Rebecca A. Gardner, Juliane Gust, Navin Pinto, Amanda G. Paulovich, Lei Zhao, Jeffrey R. Whiteaker, Evan W. Newell, Tony Chour, Rimas J. Orentas, Jason N. Wright, Francisco A. Perez, Bonnie L. Cole, Sarah E.S. Leary, Erin E. Crotty, Jessica B. Foster, Matthew D. Dun, Michael E. Berens, Jeffrey G. Ojemann, Amy Lee, Jason S. Hauptman, Samuel R. Browd, Catherine M. Albert, Stephanie D. Rawlings-Rhea, Carrie Myers, Matthew C. Biery, Michael Meechan, Aquene N. Reid, Ryan W. Koning, Blake A. Baxter, Adam J. Johnson, Jason K. Yokoyama, Joshua A. Gustafson, Christopher Brown, Kristy Seidel, Wenjun Huang, Ashley L. Wilson, Nicholas A. Vitanza
Diffuse intrinsic pontine glioma (DIPG) remains a fatal brainstem tumor demanding innovative therapies. As B7-H3 (CD276) is expressed on central nervous system (CNS) tumors, we designed B7-H3–specific chimeric antigen receptor (CAR) T cells, confir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4067a486b2678d4a886a294e60b09ff9
https://doi.org/10.1158/2159-8290.c.6549724.v1
https://doi.org/10.1158/2159-8290.c.6549724.v1
Autor:
Julie R. Park, Michael C. Jensen, Rebecca A. Gardner, Juliane Gust, Navin Pinto, Amanda G. Paulovich, Lei Zhao, Jeffrey R. Whiteaker, Evan W. Newell, Tony Chour, Rimas J. Orentas, Jason N. Wright, Francisco A. Perez, Bonnie L. Cole, Sarah E.S. Leary, Erin E. Crotty, Jessica B. Foster, Matthew D. Dun, Michael E. Berens, Jeffrey G. Ojemann, Amy Lee, Jason S. Hauptman, Samuel R. Browd, Catherine M. Albert, Stephanie D. Rawlings-Rhea, Carrie Myers, Matthew C. Biery, Michael Meechan, Aquene N. Reid, Ryan W. Koning, Blake A. Baxter, Adam J. Johnson, Jason K. Yokoyama, Joshua A. Gustafson, Christopher Brown, Kristy Seidel, Wenjun Huang, Ashley L. Wilson, Nicholas A. Vitanza
Supplementary Data from Intraventricular B7-H3 CAR T Cells for Diffuse Intrinsic Pontine Glioma: Preliminary First-in-Human Bioactivity and Safety
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c7f1c03edf81eee74a2a24740e9108e
https://doi.org/10.1158/2159-8290.22541686
https://doi.org/10.1158/2159-8290.22541686
Autor:
Cameron J. Turtle, David G. Maloney, Stanley R. Riddell, Kathleen R. Fink, Tahsin Özpolat, Susanna Harju-Baker, Dominic Chung, Junmei Chen, Jose A. Lopez, Mark Wurfel, W. Conrad Liles, Cecilia Yeung, Luis F. Gonzalez-Cuyar, David Myerson, Daniel Li, Laïla-Aïcha Hanafi, Kevin A. Hay, Juliane Gust
Supplementary Figure 4. Activation of HUVECs by serum from patients with neurotoxicity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48b979e4ff59789b75001ea7f489f9c3
https://doi.org/10.1158/2159-8290.22532444
https://doi.org/10.1158/2159-8290.22532444
Autor:
Cameron J. Turtle, David G. Maloney, Stanley R. Riddell, Kathleen R. Fink, Tahsin Özpolat, Susanna Harju-Baker, Dominic Chung, Junmei Chen, Jose A. Lopez, Mark Wurfel, W. Conrad Liles, Cecilia Yeung, Luis F. Gonzalez-Cuyar, David Myerson, Daniel Li, Laïla-Aïcha Hanafi, Kevin A. Hay, Juliane Gust
Supplementary methods, figure legends, and Supplementary Table 1. Lymphodepletion regimens prior to CAR-T cell infusion; Supplementary Table 2. Neurologic adverse event terms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ddb6062ee0a7573f471e592c7470672
https://doi.org/10.1158/2159-8290.22532429.v1
https://doi.org/10.1158/2159-8290.22532429.v1
Publikováno v:
Blood.
With growing indications for Chimeric Antigen Receptor (CAR) T-cell therapy, toxicity profiles are evolving. There is an urgent and unmet need for approaches to optimally manage emerging adverse events that extend beyond the standard paradigm of cyto