Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Juliane, Glaubitz"'
Autor:
Rabea Lange, Juliane Glaubitz, Fabian Frost, Andreas Geisz, Ali A. Aghdassi, F. Ulrich Weiss, Matthias Sendler
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract The exocrine pancreas is the main source of digestive enzymes which are released from secretory vesicles of acinar cells into the small intestine. Enzymes, including amylases, proteases and lipases, degrade the ingested food and thus determi
Externí odkaz:
https://doaj.org/article/4e784e7b78f54ba38d5075d7823f12f8
Autor:
Franziska G. Thiel, Saeedeh Asgarbeik, Juliane Glaubitz, Anika Wilden, Markus M. Lerch, Frank Ulrich Weiss, Matthias Sendler
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Acute pancreatitis (AP), which is characterized by self-digestion of the pancreas by its own prematurely activated digestive proteases, is a major reason for hospitalization. The autodigestive process causes necrotic cell death of pancreatic
Externí odkaz:
https://doaj.org/article/a0b7bc8c0135489c964a26e3672dc64a
Autor:
Juliane Glaubitz, Saeedeh Asgarbeik, Rabea Lange, Hala Mazloum, Hager Elsheikh, Frank Ulrich Weiss, Matthias Sendler
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Acute pancreatitis (AP) is one of the most common inflammatory diseases of the gastrointestinal tract and a steady rising diagnosis for inpatient hospitalization. About one in four patients, who experience an episode of AP, will develop chronic pancr
Externí odkaz:
https://doaj.org/article/a92272404a7f4303b622b15892ebbe70
Autor:
Juliane Glaubitz, Anika Wilden, Janine Golchert, Georg Homuth, Uwe Völker, Barbara M. Bröker, Thomas Thiele, Markus M. Lerch, Julia Mayerle, Ali A. Aghdassi, Frank U. Weiss, Matthias Sendler
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
The function of T regulatory cells in the tissue fibrosis in chronic pancreatitis is not fully understood. Here the authors use a mouse model of chronic pancreatitis to show that Treg cells reduce IL-4 mediated chronic inflammation in the pancreas as
Externí odkaz:
https://doaj.org/article/332d0ba357ad49519705c0efff46dce0
Autor:
Anika Wilden, Juliane Glaubitz, Oliver Otto, Doreen Biedenweg, Matthias Nauck, Matthias Mack, Silvia Ribback, Barbara M. Bröker, Sabrina Freiin von Rheinbaben, Markus M. Lerch, Ali Alexander Aghdassi, Frank Ulrich Weiss, Matthias Sendler
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
ObjectiveAcute pancreatitis (AP) is an inflammatory disorder, the severe form of which is burdened with multi-organ dysfunction and high mortality. The pathogenesis of life –threatening organ complications, such as respiratory and renal failure, is
Externí odkaz:
https://doaj.org/article/d1e9aa03df9f4fc689f8cc3d1042bf04
Autor:
Quang Trung Tran, Matthias Sendler, Mats L. Wiese, Julia Doller, Lukas Zierke, Marcel Gischke, Juliane Glaubitz, Van Huy Tran, Michael Lalk, Uwe T. Bornscheuer, Frank Ulrich Weiss, Markus M. Lerch, Ali A. Aghdassi
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 13592 (2022)
Acute pancreatitis (AP) is a major, globally increasing gastrointestinal disease and a biliary origin is the most common cause. However, the effects of bile acids (BAs), given systemically, on the pancreas and on disease severity remains elusive. In
Externí odkaz:
https://doaj.org/article/a4b7e7b0a3d346f0bac0852243595405
Autor:
Juliane Glaubitz, Markus M. Lerch, Jens Peter Kühn, Péter Hegyi, Ujjwal M. Mahajan, Petra Pallagi, Matthias Sendler, Julia Mayerle, Viktória Venglovecz, Zoltán Rakonczay, Simon Trapp, Marie-Luise Kromrey, Frank Ulrich Weiss, Ali A. Aghdassi
Publikováno v:
Journal of Cellular and Molecular Medicine
Mutations in the cystic fibrosis transmembrane conductance regulator gene (CFTR) are an established risk factor for cystic fibrosis (CF) and chronic pancreatitis. Whereas patients with CF usually develop complete exocrine pancreatic insufficiency, pa
Autor:
Julia Mayerle, Frank Ulrich Weiss, Juliane Glaubitz, Cindy van den Brandt, Anika Wilden, Barbara M. Bröker, Markus M. Lerch, Matthias Sendler
Publikováno v:
Pancreatology. 20:1637-1647
Background Acute pancreatitis is a gastrointestinal disorder of high incidence resulting in life threatening complications in up to 20% of patients. Its severe form is characterized by an extensive and systemic immune response. We investigated the ro
Autor:
Juliane Glaubitz, Anika Wilden, Fabian Frost, Sabine Ameling, Georg Homuth, Hala Mazloum, Malte Christoph Rühlemann, Corinna Bang, Ali A Aghdassi, Christoph Budde, Tilmann Pickartz, Andre Franke, Barbara M Bröker, Uwe Voelker, Julia Mayerle, Markus M Lerch, Frank-Ulrich Weiss, Matthias Sendler
Publikováno v:
Gut. :gutjnl-2022
ObjectiveIn acute pancreatitis (AP), bacterial translocation and subsequent infection of pancreatic necrosis are the main risk factors for severe disease and late death. Understanding how immunological host defence mechanisms fail to protect the inte
Publikováno v:
Pancreatology. 22:e26