Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Juliana Velez Lujan"'
Autor:
Manoj Kumar Kashyap, Hiren Karathia, Deepak Kumar, Roberto Vera Alvarez, Jose Vicente Forero-Forero, Eider Moreno, Juliana Velez Lujan, Carlos Ivan Amaya-Chanaga, Newton Medeiros Vidal, Zhe Yu, Emanuela M. Ghia, Paula A. Lengerke-Diaz, Daniel Achinko, Michael Y. Choi, Laura Z. Rassenti, Leonardo Mariño-Ramírez, Stephen M. Mount, Sridhar Hannenhalli, Thomas J. Kipps, Januario E. Castro
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 2, Pp 102202- (2024)
Splicing factor 3b subunit 1 (SF3B1) is the largest subunit and core component of the spliceosome. Inhibition of SF3B1 was associated with an increase in broad intron retention (IR) on most transcripts, suggesting that IR can be used as a marker of s
Externí odkaz:
https://doaj.org/article/adf59c81f6f94126a63b606708311ab5
Autor:
Januario E. Castro, Paula A. Lengerke-Diaz, Juliana Velez Lujan, Michael Y. Choi, Eider F. Moreno-Cortes, Jose V. Forero, Juan Esteban Garcia-Robledo, Chaja Jacobs, Colin McCarthy, Alaina Heinen, Carlos I. Amaya-Chanaga, Thomas J. Kipps
Publikováno v:
Advances in Hematology, Vol 2022 (2022)
Ibrutinib-based therapies are costly and require continuous administration. We hypothesized combining BTK inhibition with anti-CD20 monoclonal antibodies would yield deep remissions allowing discontinuation. We enrolled 32 therapy-naïve CLL patients
Externí odkaz:
https://doaj.org/article/4b490b66d62e48f895bce6b2d0f5c71a
Autor:
Juliana Velez Lujan, Paula A. Lengerke-Diaz, Chaja Jacobs, Eider F. Moreno-Cortes, Cesar A. Ramirez-Segura, Michael Y. Choi, Colin McCarthy, Alaina Heinen, Thomas J. Kipps, Januario E. Castro
Publikováno v:
Haematologica, Vol 105, Iss 1 (2020)
Externí odkaz:
https://doaj.org/article/3223f9545c044e6aae193db6725df666
Autor:
Pratip K. Bhattacharya, Marina Konopleva, David Piwnica-Worms, Christopher G. Wood, Tianyu Cai, Steven W. Millward, Prasanta Dutta, Juliana Velez Lujan, Jaehyuk Lee, Sriram S. Shanmugavelandy, Natalia Baran, Niki M. Zacharias
Figure S1-S4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c252430f90a33f1c6963ab29d8d02104
https://doi.org/10.1158/1535-7163.22507117.v1
https://doi.org/10.1158/1535-7163.22507117.v1
Autor:
Pratip K. Bhattacharya, Marina Konopleva, David Piwnica-Worms, Christopher G. Wood, Tianyu Cai, Steven W. Millward, Prasanta Dutta, Juliana Velez Lujan, Jaehyuk Lee, Sriram S. Shanmugavelandy, Natalia Baran, Niki M. Zacharias
Acute myeloid leukemia (AML) is an aggressive hematopoietic disease characterized by glutamine-dependent metabolism. A novel glutaminase (GLS) inhibitor, CB-839, is currently under evaluation for treatment of hematopoietic malignancies and solid tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a9d83300ae259ab7160882beb37b148
https://doi.org/10.1158/1535-7163.c.6538591.v1
https://doi.org/10.1158/1535-7163.c.6538591.v1
Autor:
Juliana Velez Lujan, Hannah Fields, Kan Xing Wu, Natalie Epstein, Florence Chioh, Nicholas Tan, Daniel Carbajo, Neeraja Kulkarni, Lorenz Gerber, Yovita Purwanti, Alessandra Nardin, Michael Fehlings, Katja Fink, Dan Macleod
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Manoj Kumar Kashyap, Hiren Karathia, Deepak Kumar, Roberto Vera Alvarez, Paula A Lengerke-Diaz, Jose Vicente Forero-Forero, Eider Moreno, Juliana Velez Lujan, Carlos Ivan Amaya-Chanaga, Newton Medeiros Vidal, Zhe Yu, Daniel Achinko, Emanuela M. Ghia, Michael Y. Choi, Laura Z. Rassenti, Leonardo Mariño-Ramírez, Stephen M. Mount, Sridhar Hannenhalli, Thomas J. Kipps, Januario E. Castro
BackgroundAlternative splicing (AS) is a fundamental process in eukaryotes contributing to the diversity of mRNA isoforms with variable ratios of intron/exon. SF3B1 is a pivotal protein of the spliceosome machinery. Mutations in the SF3B1 gene have p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9780fc833c4337eeaff49ae6153d3bf
https://doi.org/10.21203/rs.3.rs-1622375/v1
https://doi.org/10.21203/rs.3.rs-1622375/v1
Autor:
Juliana Velez-Lujan, Jose V. Forero, Paula A. Lengerke-Diaz, Carlos I. Amaya-Chanaga, Alaina Heinen, Juan Esteban Garcia-Robledo, Colin McCarthy, Michale Y. Choi, Eider F. Moreno-Cortes, Chaja Jacobs, Thomas J. Kipps, Januario E. Castro
Publikováno v:
Advances in Hematology, Vol 2022 (2022)
Advances in Hematology
Advances in Hematology
Ibrutinib-based therapies are costly and require continuous administration. We hypothesized combining BTK inhibition with anti-CD20 monoclonal antibodies would yield deep remissions allowing discontinuation. We enrolled 32 therapy-naïve CLL patients
Autor:
Carlos I. Amaya-Chanaga, Juliana Velez-Lujan, Januario E. Castro, Paula A Lengerke Diaz, Michael Y. Choi, Eider F. Moreno Cortes, Thomas J. Kipps, Jose V. Forero
Publikováno v:
Blood. 136:33-34
Single oral targeted therapies have emerged as a standard of care in chronic lymphocytic leukemia (CLL). However, accessibility, side effects, and financial burden associated with long term administration limit their clinical use. Mainly, it is uncle
Autor:
Cesar A Ramirez-Segura, Juliana Velez Lujan, Chaja Jacobs, Alaina Heinen, Thomas J. Kipps, Eider F. Moreno-Cortes, Paula A. Lengerke-Diaz, Januario E. Castro, Michael Y. Choi, Colin McCarthy
Publikováno v:
Haematologica. 105(1)