Výsledky vyhledávání - "Juliana S. David"

Ligand-based design, synthesis and biochemical evaluation of potent and selective inhibitors of Schistosoma mansoni dihydroorotate dehydrogenase

Autor: Marcelo Santos Castilho, Flavio da Silva Emery, Felipe A. Calil, Juliana S. David, Rodrigo Brito de Mello, Franco Henrique Andrade Leite, Estela R. C. Chiappetta, M. Cristina Nonato, Fernando Fumagalli

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Schistosomiasis ranks second only to malaria as the most common parasitic disease worldwide. 700 million people are at risk and 240 million are already infected. Praziquantel is the anthelmintic of choice but decreasing efficacy has already been docu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a59f6b4d92d3b18d42c8ad02c3fbdf6
https://doi.org/10.1016/j.ejmech.2019.02.018

Zobrazit plný text záznamu

Structural basis for the design of selective inhibitors for Schistosoma mansoni dihydroorotate dehydrogenase

Autor: Felipe A. Calil, Giovani P. Tomaleri, Renata A.G. Reis, Juliana S. David, Humberto D'Muniz Pereira, Ricardo A.P. de Pádua, M. Cristina Nonato

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Trematode worms of the genus Schistosoma are the causing agents of schistosomiasis, a parasitic disease responsible for a considerable economic and healthy burden worldwide. In the present work, the characterization of the enzyme dihydroorotate dehyd

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c49620f0f660157f21bef20ee2e7a89e

Zobrazit plný text záznamu

ThermoFMN: a thermofluor assay developed for ligand-screening as an alternative strategy for drug discovery

Autor: Giovani P. Tomaleri, Ricardo A.P. de Pádua, Matheus Pinto Pinheiro, Valéria Costa Evangelista da Silva, Maria Cristina Nonato, Renata A.G. Reis, Juliana S. David

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Journal of the Brazilian Chemical Society, Volume: 25, Issue: 10, Pages: 1864-1871, Published: OCT 2014
ResearcherID
Maria Cristina Nonato
Journal of the Brazilian Chemical Society v.25 n.10 2014
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ

A tecnica de Termofluor constitui uma importante ferramenta na identificacao de moleculas prototipos a farmacos. No presente trabalho, foi desenvolvido um metodo alternativo para a tecnica de Termofluor, chamado ThermoFMN, que explora o grupo prostet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6833b9cb58fd10f440297ad64fc60b9

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání