Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Juliana Rezende Dutra"'
Autor:
Akul Singhania, John Pham, Rekha Dhanwani, April Frazier, Juliana Rezende Dutra, Karen S. Marder, Elizabeth Phillips, Simon Mallal, Amy W. Amara, David G. Standaert, David Sulzer, Bjoern Peters, Alessandro Sette, Cecilia S. Lindestam Arlehamn
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract The self-antigen α-synuclein (α-syn) was recently shown to be associated with Parkinson’s disease (PD). Here we mapped the T cell receptor (TCR) repertoire of α-syn-specific T cells from six PD patients. The self-antigen α-syn-specific
Externí odkaz:
https://doaj.org/article/318a19c555da466f96aa22f94ae2ea3c
Autor:
Cecilia S. Lindestam Arlehamn, Rekha Dhanwani, John Pham, Rebecca Kuan, April Frazier, Juliana Rezende Dutra, Elizabeth Phillips, Simon Mallal, Mario Roederer, Karen S. Marder, Amy W. Amara, David G. Standaert, Jennifer G. Goldman, Irene Litvan, Bjoern Peters, David Sulzer, Alessandro Sette
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
α-Synuclein-specific T cell reactivity is preferentially associated with Parkinson’s disease (PD) patients, but the temporal relation with diagnosis was previously unknown. This study reveals that α-syn-reactive T cells are highest before and sho
Externí odkaz:
https://doaj.org/article/9731c07b2438479d8928e5d35c33b9a6
Autor:
Rekha Dhanwani, John Pham, Ashmitaa Logandha Ramamoorthy Premlal, April Frazier, Atul Kumar, Maria Elena Pero, Francesca Bartolini, Juliana Rezende Dutra, Karen S. Marder, Bjoern Peters, David Sulzer, Alessandro Sette, Cecilia S. Lindestam Arlehamn
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2021)
Externí odkaz:
https://doaj.org/article/da236d6c7c7741f7b65ebd5354e3f33f
Autor:
Rekha Dhanwani, John Pham, Ashmitaa Logandha Ramamoorthy Premlal, April Frazier, Atul Kumar, Maria Elena Pero, Francesca Bartolini, Juliana Rezende Dutra, Karen S. Marder, Bjoern Peters, David Sulzer, Alessandro Sette, Cecilia S. Lindestam Arlehamn
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Alzheimer’s disease (AD), a chronic multifactorial and complex neurodegenerative disorder is a leading cause of dementia. Recently, neuroinflammation has been hypothesized as a contributing factor to AD pathogenesis. The role of adaptive immune res
Externí odkaz:
https://doaj.org/article/6c47451504414c0e916af5965b96f6e2
Autor:
Simon Mallal, Karen Marder, April Frazier, Bjoern Peters, John Pham, Akul Singhania, Rekha Dhanwani, Juliana Rezende Dutra, David Sulzer, Cecilia S. Lindestam Arlehamn, David G. Standaert, Alessandro Sette, Amy W. Amara, Elizabeth J. Phillips
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports
Scientific Reports
The self-antigen α-synuclein (α-syn) was recently shown to be associated with Parkinson’s disease (PD). Here we mapped the T cell receptor (TCR) repertoire of α-syn-specific T cells from six PD patients. The self-antigen α-syn-specific repertoi
Autor:
Rekha Dhanwani, John Pham, Ashmitaa Logandha Ramamoorthy Premlal, April Frazier, Atul Kumar, Maria Elena Pero, Francesca Bartolini, Juliana Rezende Dutra, Karen S. Marder, Bjoern Peters, David Sulzer, Alessandro Sette, Cecilia S. Lindestam Arlehamn
Publikováno v:
Frontiers in Neuroscience
Frontiers in Neuroscience, Vol 14 (2020)
Frontiers in Neuroscience, Vol 14 (2021)
Frontiers in Neuroscience, Vol 14 (2020)
Frontiers in Neuroscience, Vol 14 (2021)
Alzheimer’s disease (AD), a chronic multifactorial and complex neurodegenerative disorder is a leading cause of dementia. Recently, neuroinflammation has been hypothesized as a contributing factor to AD pathogenesis. The role of adaptive immune res
Autor:
Cecilia S, Lindestam Arlehamn, Rekha, Dhanwani, John, Pham, Rebecca, Kuan, April, Frazier, Juliana, Rezende Dutra, Elizabeth, Phillips, Simon, Mallal, Mario, Roederer, Karen S, Marder, Amy W, Amara, David G, Standaert, Jennifer G, Goldman, Irene, Litvan, Bjoern, Peters, David, Sulzer, Alessandro, Sette
Publikováno v:
Nature communications. 11(1)
A diagnosis of motor Parkinson's disease (PD) is preceded by a prolonged premotor phase with accumulating neuronal damage. Here we examined the temporal relation between α-synuclein (α-syn) T cell reactivity and PD. A longitudinal case study reveal
Autor:
Simon Mallal, Bjoern Peters, April Frazier, Rekha Dhanwani, Juliana Rezende Dutra, Mario Roederer, Cecilia S. Lindestam Arlehamn, Karen Marder, David Sulzer, Amy W. Amara, David G. Standaert, Alessandro Sette, Jennifer G. Goldman, Rebecca Kuan, John Pham, Elizabeth J. Phillips, Irene Litvan
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
A clinical diagnosis of motor Parkinson’s disease (PD) is preceded by a prolonged premotor phase with accumulating neuronal damage. α-Synuclein (α-syn)-specific T cell reactivity is preferentially associated with PD patients. Here we examined the
Publikováno v:
Current Neurology and Neuroscience Reports. 15
The diagnostic hallmarks of hippocampal sclerosis (HS) are severe volume loss of the hippocampus, severe neuronal loss, and reactive gliosis involving primarily two especially vulnerable fields, CA1 and the subiculum. Occasionally, HS may be the only