Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Juliana M.C. Barbosa"'
Autor:
Ana Cristina S. Bombaça, Leonardo A. Silva, Otávio Augusto Chaves, Lorrainy S. da Silva, Juliana M.C. Barbosa, Ari M. da Silva, Aurélio B.B. Ferreira, Rubem F.S. Menna-Barreto
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 135, Iss , Pp 111186- (2021)
Trypanosoma cruzi is a protozoan parasite that causes Chagas disease, a neglected tropical disease that is endemic in Latin America and spreading worldwide due to globalization. The current treatments are based on benznidazole and nifurtimox; however
Externí odkaz:
https://doaj.org/article/ddbceab790d64343b85195e85a9334b9
Autor:
Rosana H.C.N. Freitas, Juliana M.C. Barbosa, Patrícia Bernardino, Vitor Sueth-Santiago, Solange M.S.V. Wardell, James L. Wardell, Débora Decoté-Ricardo, Tatiana G. Melo, Edson F. da Silva, Kelly Salomão, Carlos A.M. Fraga
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 127, Iss , Pp 110162- (2020)
Herein, we present the design, synthesis and trypanocidal evaluation of sixteen new 1,3,4-thiadiazole derivatives from N-aminobenzyl or N-arylhydrazone series. All derivatives were assayed against the trypomastigote form of Trypanosoma cruzi, showing
Externí odkaz:
https://doaj.org/article/2913247f852a4bbe8cac3322fa6ea291
Autor:
Carlos A.M. Fraga, Giulianna P. de Alcântara, Juliana M.C. Barbosa, Kelly Salomão, Solange L. de Castro, James L. Wardell, John N. Low, Solange M.S.V. Wardell, Samir A. Carvalho, Edson F. da Silva
Publikováno v:
Letters in Drug Design & Discovery. 20:488-497
Background: The drugs available for the treatment of Chagas disease are ineffective in its chronic phase and produce many adverse effects, making the search for new drugs an urgent medical need. Objective: This study aimed to design, synthesize, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::508b257477d31508daa851213480b21f
https://doi.org/10.2174/1570180819666220512121029
https://doi.org/10.2174/1570180819666220512121029