Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Juliana M. Figueiredo"'
Autor:
Juliana M. Figueiredo, S. Michal Jazwinski, Norton Heise, Carolina M. Koeller, Deivid C. Rodrigues, James C. Jiang, Lucia Mendonça-Previato, Rafael Cardoso Maciel Costa Silva, José O. Previato, Turán P. Ürményi
Publikováno v:
Molecular and Biochemical Parasitology. 182:62-74
In this study, we characterized ceramide synthase (CerS) of the protozoan parasite Trypanosoma cruzi at the molecular and functional levels. TcCerS activity was detected initially in a cell-free system using the microsomal fraction of epimastigote fo
Autor:
Ana L.P. Miranda, Carlos Rangel Rodrigues, Juliana M. Figueiredo, Carlos A. M. Fraga, Celso de Amorim Câmara, Eliezer J. Barreiro, Fúlvia M Santos, Emanuel G. Amarante
Publikováno v:
Bioorganic & Medicinal Chemistry. 8:2243-2248
This paper describes recent results of design, synthesis and pharmacological evaluation of new N -heterocyclic functionalized N -acylhydrazone compounds, belonging to the 2-methyl-imidazolyl-3-acylhydrazone class ( 4a – e ). These compounds were pl
Autor:
Lucia Mendonça-Previato, Norton Heise, Juliana M. Figueiredo, José O. Previato, Wagner B. Dias
IPC (inositol phosphorylceramide) synthase is an enzyme essential for fungal viability, and it is the target of potent antifungal compounds such as rustmicin and aureobasidin A. Similar to fungi and some other lower eukaryotes, the protozoan parasite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c832ce01cdcb46c6e722a67ce3b5669
https://europepmc.org/articles/PMC1134981/
https://europepmc.org/articles/PMC1134981/
Autor:
Ana L.P. Miranda, Helena Carla Castro, Russolina B. Zingali, Vitor F. Ferreira, Anna C. Cunha, Jorge L. M. Tributino, Juliana M. Figueiredo, Carlos A. M. Fraga, Eliezer J. Barreiro, Maria Cecília B. V. de Souza
Publikováno v:
Bioorganicmedicinal chemistry. 11(9)
This paper describes the design, synthesis and pharmacological evaluation of new N-acylhydrazone (NAH) compounds, belonging to the N-substituted-phenyl-1,2,3-triazole-4-acylhydrazone class (2a-p). Classical heteroaromatic ring bioisosterism strategie