Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Juliana M, Sá"'
Autor:
Brittany Hazzard, Juliana M. Sá, Haikel N. Bogale, Tales V. Pascini, Angela C. Ellis, Shuchi Amin, Jennifer S. Armistead, John H. Adams, Thomas E. Wellems, David Serre
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Most Plasmodium vivax infections contain genetically distinct parasites, but the consequences of this polyclonality on the development of asexual parasites, their sexual differentiation, and their transmission remain unknown. We describe inf
Externí odkaz:
https://doaj.org/article/0a2b0dece0d746098ac2d4e0675fe134
Autor:
Kristina K. Gonzales-Wartz, Juliana M. Sá, Kevin Lee, Yonas Gebremicale, Bingbing Deng, Carole A. Long, Tales V. Pascini, Andre Laughinghouse, Samuel E. Moretz, Ana M. Ortega-Villa, Michael P. Fay, Thomas E. Wellems
Publikováno v:
Parasites & Vectors, Vol 17, Iss 1, Pp 1-15 (2024)
Abstract Background Aedes and Anopheles mosquitoes are responsible for tremendous global health burdens from their transmission of pathogens causing malaria, lymphatic filariasis, dengue, and yellow fever. Innovative vector control strategies will he
Externí odkaz:
https://doaj.org/article/a1e0e45d04a44e9b8e8a4a8bce51bb3f
Autor:
Tales V. Pascini, Yeong Je Jeong, Wei Huang, Zarna R. Pala, Juliana M. Sá, Michael B. Wells, Christopher Kizito, Brendan Sweeney, Thiago L. Alves e Silva, Deborah J. Andrew, Marcelo Jacobs-Lorena, Joel Vega-Rodríguez
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Plasmodium gametes and sporozoites activate surface-bound plasminogen to plasmin that degrades extracellular matrix barriers, therewith facilitating parasite motility in mosquitoes and mammalian hosts. To control malaria transmission, Pascini et al.
Externí odkaz:
https://doaj.org/article/6637f4de56264305b96cb1a12269a4bd
Autor:
Brittany Hazzard, Juliana M Sá, Angela C Ellis, Tales V Pascini, Shuchi Amin, Thomas E Wellems, David Serre
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 12, p e0010991 (2022)
Plasmodium vivax infections often consist of heterogenous populations of parasites at different developmental stages and with distinct transcriptional profiles, which complicates gene expression analyses. The advent of single cell RNA sequencing (scR
Externí odkaz:
https://doaj.org/article/81e01b1098fc43839c9f89db47698422
Autor:
Roberto R. Moraes Barros, Kittisak Thawnashom, Tyler J. Gibson, Jennifer S. Armistead, Ramoncito L. Caleon, Miho Kaneko, Whitney A. Kite, J. Patrick Mershon, Jacqueline K. Brockhurst, Theresa Engels, Lynn Lambert, Sachy Orr-Gonzalez, John H. Adams, Juliana M. Sá, Osamu Kaneko, Thomas E. Wellems
Publikováno v:
Malaria Journal, Vol 20, Iss 1, Pp 1-13 (2021)
Abstract Background Plasmodium knowlesi is now the major cause of human malaria in Malaysia, complicating malaria control efforts that must attend to the elimination of multiple Plasmodium species. Recent advances in the cultivation of P. knowlesi er
Externí odkaz:
https://doaj.org/article/5a5b110a481a498abb64be09b5fb8509
Autor:
Sean T. Windle, Kristin D. Lane, Nahla B. Gadalla, Anna Liu, Jianbing Mu, Ramoncito L. Caleon, Rifat S. Rahman, Juliana M. Sá, Thomas E. Wellems
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 14, Iss , Pp 208-217 (2020)
Background: Lumefantrine and mefloquine are used worldwide in artemisinin-based combination therapy (ACT) of malaria. Better understanding of drug susceptibility and resistance is needed and can be obtained from studies of genetic crosses. Methods: D
Externí odkaz:
https://doaj.org/article/03ffa978d77c4154a1e5c0ec24f5c94f
Autor:
Juliana M. Sá, Sarah R. Kaslow, Roberto R. Moraes Barros, Nicholas F. Brazeau, Christian M. Parobek, Dingyin Tao, Rebecca E. Salzman, Tyler J. Gibson, Soundarapandian Velmurugan, Michael A. Krause, Viviana Melendez-Muniz, Whitney A. Kite, Paul K. Han, Richard T. Eastman, Adam Kim, Evan G. Kessler, Yonas Abebe, Eric R. James, Sumana Chakravarty, Sachy Orr-Gonzalez, Lynn E. Lambert, Theresa Engels, Marvin L. Thomas, Pius S. Fasinu, David Serre, Robert W. Gwadz, Larry Walker, Derrick K. DeConti, Jianbing Mu, Jeffrey A. Bailey, B. Kim Lee Sim, Stephen L. Hoffman, Michael P. Fay, Rhoel R. Dinglasan, Jonathan J. Juliano, Thomas E. Wellems
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Here, a cross of Plasmodium vivax malaria parasites links a chloroquine resistance (CQR) phenotype to a 76 kb region of chromosome 1 and greater expression of pvcrt, an ortholog of the Plasmodium falciparum CQR transporter gene.
Externí odkaz:
https://doaj.org/article/d2e5b78b5b7d41ea85f525fdaf910313
Autor:
Sean V. Connelly, Javier Manzella-Lapeira, Zoë C. Levine, Joseph Brzostowski, Ludmila Krymskaya, Rifat S. Rahman, Angela C. Ellis, Shuchi N. Amin, Juliana M. Sá, Thomas E. Wellems
Publikováno v:
mBio, Vol 12, Iss 3 (2021)
The major first-line treatment for malaria, especially the deadliest form caused by Plasmodium falciparum
Externí odkaz:
https://doaj.org/article/31fdd0b4cec14451bead7dd21644d70a
Autor:
Christine E. Figan, Juliana M. Sá, Jianbing Mu, Viviana A. Melendez-Muniz, Chia Hao Liu, Thomas E. Wellems
Publikováno v:
Malaria Journal, Vol 17, Iss 1, Pp 1-6 (2018)
Abstract Background Four Plasmodium falciparum genetic crosses (HB3×3D7, HB3×Dd2, 7G8×GB4, and 803×GB4) have produced sets of recombinant progeny that are widely used for malaria research, including investigations of anti-malarial drug resistance
Externí odkaz:
https://doaj.org/article/8ba0a16eb611405bbeb3e2e1870d26f6
Autor:
Brajesh K. Singh, Cui Zhang, Jian Wu, Yu-Chih Peng, Xiao He, Keyla C. Tumas, Juliana M. Sá, Kristin D. Lane, Richard T. Eastman, David L. Narum, Thomas E. Wellems, Xin-zhuan Su
Publikováno v:
Antimicrobial Agents and Chemotherapy. 67
Protein ubiquitination is an important posttranslational regulation mechanism that mediates Plasmodium development and modifies parasite responses to antimalarial drugs. Although mutations in several parasite ubiquitination enzymes have been linked t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06b225fbefe99850c5383e306e589829
https://doi.org/10.1128/aac.00821-22
https://doi.org/10.1128/aac.00821-22