Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Juliana J. Conkright"'
Publikováno v:
Proceedings of the American Thoracic Society. 7:415-422
The function of the human proteome is defined by the proteostasis network (PN) (Science 2008;319:916; Science 2010;329:766), a biological system that generates, protects, and, where necessary, degrades a protein to optimize the cell, tissue, and orga
Autor:
Baoli Yang, Karen S. Apsley, Ross A. Ridsdale, Juliana J. Conkright, Ward R. Rice, Timothy E. Weaver, Cheng-Lun Na, Emily P. Martin
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 42:181-189
We previously proposed a model of surfactant protein (SP)-C biosynthesis in which internalization of the proprotein from the limiting membrane of the multivesicular body to internal vesicles represents a key step in the processing and secretion of SP
Autor:
Ward R. Rice, Juliana J. Conkright, Cheng-Lun Na, Machiko Ikegami, Timothy E. Weaver, John M. Shannon
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 283:L256-L264
The purpose of this study was to identify culture conditions for maintenance of isolated mouse type II cells with intact surfactant protein (SP) and phospholipid production. Type II cells were isolated from 6-wk-old mice and cultured on Matrigel matr
Autor:
Stephan W. Glasser, Peter D. Sly, Jeffrey A. Whitsett, Timothy E. Weaver, Gary F. Ross, Machiko Ikegami, Juliana J. Conkright
Publikováno v:
Journal of Applied Physiology. 92:519-526
Although the surface properties of surfactant protein (SP)-B and SP-C are similar, the contributions that either protein may make to lung function have not been identified in vivo. Mutations in SP-B cause lethal respiratory failure at birth; however,
Autor:
Juliana J. Conkright, Thomas P. Burris, William R. Roush, Monica A. Istrate, Naresh Kumar, Dana S. Kuruvilla, Patrick R. Griffin, Theodore M. Kamenecka, Yongjun Wang, Scott A. Busby, Michael D. Cameron
Publikováno v:
ACS chemical biology. 6(6)
Retinoids are potent forms of vitamin A and are involved in a broad range of physiological processes and the pharmacological effects of retinoids are primarily mediated by the retinoic acid receptors (RARs) and the retinoid X receptors (RXRs). Severa
Autor:
Yongjun Wang, Thomas P. Burris, Monica A. Istrate, Laura A. Solt, Ruben D. Garcia-Ordonez, Patrick R. Griffin, Naresh Kumar, Juliana J. Conkright, Scott A. Busby
Publikováno v:
Molecular pharmacology. 77(2)
Retinoic acid receptor-related orphan receptors (RORs) regulate a variety of physiological processes including hepatic gluconeogenesis, lipid metabolism, circadian rhythm, and immune function. Here we present the first high-affinity synthetic ligand
Autor:
Michael D. Cameron, Juliana J. Conkright, Gina M. Zastrow, Peter Hodder, Xiaolin Li, Patrick R. Griffin, Franck Madoux, Scott Thacher, Peter Chase
Publikováno v:
Molecular pharmacology. 73(6)
The steroidogenic factor 1 (SF-1, also known as NR5A1) is a transcription factor belonging to the nuclear receptor superfamily. Whereas most of the members of this family have been extensively characterized, the therapeutic potential and pharmacology
Autor:
Valerie Cavett, Jennifer Busby, Serge Batalov, Anthony P. Orth, John B. Hogenesch, Michael D. Conkright, Loren Miraglia, Becky A. Mercer, Antonio L. Amelio, Juliana J. Conkright
Signal transduction pathways often use a transcriptional component to mediate adaptive cellular responses. Coactivator proteins function prominently in these pathways as the conduit to the basic transcriptional machinery. Here we present a high-throu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d63dcee4e62e05aeaaa775802c4a503
https://europepmc.org/articles/PMC2154428/
https://europepmc.org/articles/PMC2154428/
Publikováno v:
The Journal of biological chemistry. 274(18)
CC chemokine receptor-3 (CCR-3) is a major receptor involved in regulating eosinophil trafficking; therefore, elucidation of ligand-induced CCR-3 events has important implications in understanding the biological and pathological properties of eosinop
Autor:
Cockrell AJ; Stowers Institute for Medical Research, Kansas City, Missouri, United States of America.; Department of Biochemistry and Molecular Biology, University of Kansas Medical Center, Kansas City, Kansas, United States of America., Lange JJ; Stowers Institute for Medical Research, Kansas City, Missouri, United States of America., Wood C; Stowers Institute for Medical Research, Kansas City, Missouri, United States of America., Mattingly M; Stowers Institute for Medical Research, Kansas City, Missouri, United States of America., McCroskey SM; Stowers Institute for Medical Research, Kansas City, Missouri, United States of America., Bradford WD; Stowers Institute for Medical Research, Kansas City, Missouri, United States of America., Conkright-Fincham J; Stowers Institute for Medical Research, Kansas City, Missouri, United States of America.; Promega Corporation, Madison, Wisconsin, United States of America., Weems L; Stowers Institute for Medical Research, Kansas City, Missouri, United States of America., Guo MS; Department of Microbiology, University of Washington School of Medicine, Seattle, state of Washington, United States of America., Gerton JL; Stowers Institute for Medical Research, Kansas City, Missouri, United States of America.; Department of Biochemistry and Molecular Biology, University of Kansas Medical Center, Kansas City, Kansas, United States of America.
Publikováno v:
PLoS genetics [PLoS Genet] 2024 Jul 05; Vol. 20 (7), pp. e1011331. Date of Electronic Publication: 2024 Jul 05 (Print Publication: 2024).