Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Juliana Guimarães Santos"'
Autor:
Juliana Guimarães Santos, Wanise Maria Souza Da Cruz, Axel H. Schönthal, Marcela D'alincourt Salazar, Cristina Asvolinsque Pantaleão Fontes, Thereza Quirico-Santos, Clovis Orlando da Fonseca
Publikováno v:
Brazilian Neurosurgery, Vol 36, Iss 03, Pp 194-199 (2017)
Abstract Introduction Monoterpene perillyl alcohol (POH) is cytotoxic to temozolomide-resistant glioma cells, regardless of its O6-methylguanine-methyltransferase (MGMT) promoter methylation status. Moreover, adherence to a ketogenic diet (KD) prod
Externí odkaz:
https://doaj.org/article/b4839ec7401f46d0b448aa28c5d036ff
Autor:
Clovis Orlando da Fonseca, Cristina Asvolinsque Pantaleão Fontes, Axel H. Schönthal, Thereza Quirico-Santos, Marcela d'Alincourt Salazar, Juliana Guimarães Santos, Wanise Maria Souza Da Cruz
Publikováno v:
Brazilian Neurosurgery, Vol 36, Iss 03, Pp 194-199 (2017)
Introduction Monoterpene perillyl alcohol (POH) is cytotoxic to temozolomide-resistant glioma cells, regardless of its O6-methylguanine-methyltransferase (MGMT) promoter methylation status. Moreover, adherence to a ketogenic diet (KD) produced succes
Autor:
Gisele Faria, Cristina Asvolinsque Pantaleão Fontes, Clovis Orlando da Fonseca, Thereza Quirico-Santos, Juliana Guimarães Santos, Wanise Da Cruz Souza Da Cruz, Axel H. Schönthal
Publikováno v:
Surgical Neurology International
Background: Standard of care for glioblastoma (GB), consisting of cytotoxic chemotherapy, steroids, and high-dose radiation, induces changes in the tumor microenvironment through its effects on glucose availability, which is a determinant for tumor p
Autor:
Clovis Orlando da Fonseca, Axel H. Schönthal, Thereza Quirico Santos, Marcela d'Alincourt Salazar, Juliana Guimarães Santos, Wanise Maria Souza Da Cruz, Cristina Asvolinsque Pantaleão Fontes
Publikováno v:
Oncology Letters.
It has been hypothesized that persistent ketotic hypoglycemia represents a potential therapeutic strategy against high-grade gliomas. Perillyl alcohol (POH) is a non-toxic, naturally-occurring, hydroxylated monoterpene that exhibits cytotoxicity agai