Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Juliana E. Gentile"'
Autor:
Meredith A. Mortberg, Hien T. Zhao, Andrew G. Reidenbach, Juliana E. Gentile, Eric Kuhn, Jill O’Moore, Patrick M. Dooley, Theresa R. Connors, Curt Mazur, Shona W. Allen, Bianca A. Trombetta, Alison McManus, Matthew R. Moore, Jiewu Liu, Deborah E. Cabin, Holly B. Kordasiewicz, Joel Mathews, Steven E. Arnold, Sonia M. Vallabh, Eric Vallabh Minikel
Publikováno v:
JCI Insight, Vol 7, Iss 6 (2022)
Prion protein (PrP) concentration controls the kinetics of prion replication and is a genetically and pharmacologically validated therapeutic target for prion disease. In order to evaluate PrP concentration as a pharmacodynamic biomarker and assess i
Externí odkaz:
https://doaj.org/article/55c56ea359e34e3f8a0d1b5825c838ee
Publikováno v:
Cells, Vol 11, Iss 4, p 603 (2022)
Neurons transmit and receive information at specialized junctions called synapses. Excitatory synapses form at the junction between a presynaptic axon terminal and a postsynaptic dendritic spine. Supporting the shape and function of these junctions i
Externí odkaz:
https://doaj.org/article/62b6ce6653e04472aafe314ac477cabb
Autor:
Sarah M. Prophet, Anthony J. Rampello, Robert F. Niescier, Juliana E. Gentile, Sunanda Mallik, Anthony J. Koleske, Christian Schlieker
Publikováno v:
Nat Cell Biol
DYT1 dystonia is a debilitating neurological movement disorder arising from mutation in the AAA+ ATPase TorsinA. The hallmark of Torsin dysfunction is nuclear envelope blebbing resulting from defects in nuclear pore complex biogenesis. Whether blebs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c8ac989096b0a350f0c522606a24da6
https://doi.org/10.1038/s41556-022-01001-y
https://doi.org/10.1038/s41556-022-01001-y
Autor:
Meredith A Mortberg, Juliana E Gentile, Naeem M Nadaf, Charles Vanderburg, Sean Simmons, Dan Dubinsky, Adam Slamin, Salome Maldonado, Caroline L Petersen, Nichole Jones, Holly B Kordasiewicz, Hien T Zhao, Sonia M Vallabh, Eric Vallabh Minikel
Publikováno v:
bioRxiv
Antisense oligonucleotides (ASOs) dosed into cerebrospinal fluid (CSF) distribute broadly throughout the central nervous system (CNS). By modulating RNA, they hold the promise of targeting root molecular causes of disease and hold potential to treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34e6a0a8fdc2a55ad8c5cb4174924d46
https://doi.org/10.1101/2023.02.14.528473
https://doi.org/10.1101/2023.02.14.528473
Autor:
Ons M’Saad, Ravikiran Kasula, Ilona Kondratiuk, Phylicia Kidd, Hanieh Falahati, Juliana E. Gentile, Robert F. Niescier, Katherine Watters, Robert C. Sterner, Seong Lee, Xinran Liu, Pietro De Camilli, James E. Rothman, Anthony J. Koleske, Thomas Biederer, Joerg Bewersdorf
SummaryUnderstanding the molecular anatomy and neural connectivity of the brain requires imaging technologies that can map the 3D nanoscale distribution of specific proteins in the context of brain ultrastructure. Light and electron microscopy (EM) e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74e08273d1a251299cca52bae87aa56b
https://doi.org/10.1101/2022.04.04.486901
https://doi.org/10.1101/2022.04.04.486901
Autor:
Meredith A. Mortberg, Hien T. Zhao, Andrew G. Reidenbach, Juliana E. Gentile, Eric Kuhn, Jill O’Moore, Patrick M. Dooley, Theresa R. Connors, Curt Mazur, Shona W. Allen, Bianca A. Trombetta, Alison McManus, Matthew R. Moore, Jiewu Liu, Deborah E. Cabin, Holly B. Kordasiewicz, Joel Mathews, Steven E. Arnold, Sonia M. Vallabh, Eric Vallabh Minikel
Publikováno v:
JCI insight. 7(6)
Prion protein (PrP) concentration controls the kinetics of prion replication and is a genetically and pharmacologically validated therapeutic target for prion disease. In order to evaluate PrP concentration as a pharmacodynamic biomarker and assess i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::455d984b94d2b103b2753c34cf9aff46
https://pubmed.ncbi.nlm.nih.gov/35133987
https://pubmed.ncbi.nlm.nih.gov/35133987
Autor:
Meredith A Mortberg, Hien T Zhao, Andrew G Reidenbach, Juliana E Gentile, Eric Kuhn, Jill O’Moore, Patrick M Dooley, Theresa R Connors, Curt Mazur, Shona W Allen, Bianca A Trombetta, Alison McManus, Matthew R Moore, Jiewu Liu, Deborah E Cabin, Holly B Kordasiewicz, Joel Mathews, Steven E Arnold, Sonia M Vallabh, Eric Vallabh Minikel
Prion protein (PrP) concentration controls the kinetics of prion replication and is a genetically and pharmacologically validated therapeutic target for prion disease. In order to evaluate PrP concentration as a pharmacodynamic biomarker and assess i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19bb23600f08e727e17bcbc59299d67b
https://doi.org/10.1101/2021.11.01.21265619
https://doi.org/10.1101/2021.11.01.21265619
Autor:
Sarah M, Prophet, Anthony J, Rampello, Robert F, Niescier, Juliana E, Gentile, Sunanda, Mallik, Anthony J, Koleske, Christian, Schlieker
Publikováno v:
Nature cell biology. 24(11)
DYT1 dystonia is a debilitating neurological movement disorder arising from mutation in the AAA+ ATPase TorsinA. The hallmark of Torsin dysfunction is nuclear envelope blebbing resulting from defects in nuclear pore complex biogenesis. Whether blebs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::af5740bfdd6cd59cb0d5617c25f66810
https://pubmed.ncbi.nlm.nih.gov/36302972
https://pubmed.ncbi.nlm.nih.gov/36302972