Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Juliana Conkright"'
Autor:
Alexandria J Cockrell, Jeffrey J Lange, Christopher Wood, Mark Mattingly, Scott M McCroskey, William D Bradford, Juliana Conkright-Fincham, Lauren Weems, Monica S Guo, Jennifer L Gerton
Publikováno v:
PLoS Genetics, Vol 20, Iss 7, p e1011331 (2024)
Nucleolar morphology is a well-established indicator of ribosome biogenesis activity that has served as the foundation of many screens investigating ribosome production. Missing from this field of study is a broad-scale investigation of the regulatio
Externí odkaz:
https://doaj.org/article/1b5df90b2dd94b169054ebf987bcf056
Autor:
Tamara A Potapova, Jay R Unruh, Juliana Conkright-Fincham, Charles AS Banks, Laurence Florens, David Alan Schneider, Jennifer L Gerton
Publikováno v:
eLife, Vol 12 (2023)
Ribosome biogenesis is a vital and highly energy-consuming cellular function occurring primarily in the nucleolus. Cancer cells have an elevated demand for ribosomes to sustain continuous proliferation. This study evaluated the impact of existing ant
Externí odkaz:
https://doaj.org/article/fc3278bdd9414a3bbee3d9190e4221a8
Autor:
Juliana Conkright-Fincham, Chieri Tomomori-Sato, Rich McGhee, Ella Leslie, Carolyn Beucher, Lauren Weems, Shigeo Sato, William Redwine, Kyle Weaver, Brandon Miller, Kym Delventhal, John Kary, Andrew Koebbe, Alexander Dean, Jessica Witt, Laura Remy, Tari Parmely, Chongbei Zhao, Yan Wang, Joan Conaway, Jay Unruh
Publikováno v:
Bio-Protocol, Vol 12, Iss 2 (2022)
The SARS-CoV-2 pandemic and vaccination campaign has illustrated the need for high throughput serological assays to quantitatively measure antibody levels. Here, we present a protocol for a high-throughput colorimetric ELISA assay to detect IgG antib
Externí odkaz:
https://doaj.org/article/adea0cc7a65148f3a048b3b458c5f333
Autor:
Tamaki Suganuma, Selene K. Swanson, Madelaine Gogol, Timothy J. Garrett, Juliana Conkright-Fincham, Laurence Florens, Michael P. Washburn, Jerry L. Workman
Publikováno v:
Cell Reports, Vol 24, Iss 6, Pp 1585-1596 (2018)
Summary: Metabolic disorder has been suggested to underlie Alzheimer’s disease (AD). However, the decisive molecular linkages remain unclear. We discovered that human Molybdopterin Synthase Associating Complex, MPTAC, promotes sulfur amino acid cat
Externí odkaz:
https://doaj.org/article/452621fa20c943dd80d9338e790b6eb3
Autor:
Parama Paul, Sreekumar Ramachandran, Sheng Xia, Jay R Unruh, Juliana Conkright-Fincham, Rong Li
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216220 (2019)
Autosomal dominant polycystic kidney disease (ADPKD) is caused mostly by mutations in polycystin-1 or polycystin-2. Fluid flow leads to polycystin-dependent calcium influx and nuclear export of histone deacetylase 5 (HDAC5), which facilitates the mai
Externí odkaz:
https://doaj.org/article/e5399717e0b5480f90d8c9fb16d26725
Aneuploidy as a cause of impaired chromatin silencing and mating-type specification in budding yeast
Autor:
Wahid A Mulla, Chris W Seidel, Jin Zhu, Hung-Ji Tsai, Sarah E Smith, Pushpendra Singh, William D Bradford, Scott McCroskey, Anjali R Nelliat, Juliana Conkright, Allison Peak, Kathryn E Malanowski, Anoja G Perera, Rong Li
Publikováno v:
eLife, Vol 6 (2017)
Aneuploidy and epigenetic alterations have long been associated with carcinogenesis, but it was unknown whether aneuploidy could disrupt the epigenetic states required for cellular differentiation. In this study, we found that ~3% of random aneuploid
Externí odkaz:
https://doaj.org/article/819ebc5faddb4f61b6c2d95607a75abb
Autor:
Tamara A. Potapova, Jay R. Unruh, Juliana Conkright-Fincham, Charles A. S. Banks, Laurence Florens, David A. Schneider, Jennifer L. Gerton
Ribosome biogenesis is one of the most essential and energy-consuming cellular functions. It takes place mainly in the nucleolus. For cancer cells, the nucleolar function is especially important due to the high demand for ribosomes to support continu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b94477b8de1b94cedc502e45f8536ce3
https://doi.org/10.1101/2022.11.18.517150
https://doi.org/10.1101/2022.11.18.517150
Autor:
Joan Weliky Conaway, Jay R. Unruh, Chieri Tomomori-Sato, Leanne M. Wiedemann, Laura Remy, Juliana Conkright-Fincham
We present preliminary data in an ongoing observational study reporting SARS-CoV-2 spike protein reactive antibody levels from a convenience cohort of over 250 individuals in Kansas City. We observe stable antibody levels over one year in individuals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::921911b3f4b683bbfd018962f3e9d7fd
https://doi.org/10.1101/2021.08.16.21262036
https://doi.org/10.1101/2021.08.16.21262036
Autor:
Juliana Conkright-Fincham, Parama Paul, Rong Li, Jay R. Unruh, Sheng Xia, Sreekumar Ramachandran
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 5, p e0216220 (2019)
PLoS ONE, Vol 14, Iss 5, p e0216220 (2019)
Autosomal dominant polycystic kidney disease (ADPKD) is caused mostly by mutations in polycystin-1 or polycystin-2. Fluid flow leads to polycystin-dependent calcium influx and nuclear export of histone deacetylase 5 (HDAC5), which facilitates the mai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ccf08db17d4670644d8df5e7ba414a3
http://europepmc.org/articles/PMC6502331
http://europepmc.org/articles/PMC6502331
Autor:
Rong Li, Scott McCroskey, William D. Bradford, Wahid A. Mulla, Boris Rubinstein, Judith Berman, Hung-Ji Tsai, Juliana Conkright, Jeffrey S. Haug, Lauren Weems, Chris Seidel, Andrei Kucharavy, Guangbo Chen
Publikováno v:
Cell
Cell, 2015, 160 (4), pp.771-784. ⟨10.1016/j.cell.2015.01.026⟩
Cell, Elsevier, 2015, 160 (4), pp.771-784. ⟨10.1016/j.cell.2015.01.026⟩
Cell, 2015, 160 (4), pp.771-784. ⟨10.1016/j.cell.2015.01.026⟩
Cell, Elsevier, 2015, 160 (4), pp.771-784. ⟨10.1016/j.cell.2015.01.026⟩
International audience; Aneuploid genomes, characterized by unbalanced chromosome stoichiometry (karyotype), are associated with cancer malignancy and drug resistance of pathogenic fungi. The phenotypic diversity resulting from karyotypic diversity e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce65ea1eccb279860b4e650524cfdf92
https://doi.org/10.1016/j.cell.2015.01.026
https://doi.org/10.1016/j.cell.2015.01.026