Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Juliana Barrios"'
Autor:
Hongmei Mou, Ying Yang, Molly A. Riehs, Juliana Barrios, Manjunatha Shivaraju, Adam L. Haber, Daniel T. Montoro, Kimberly Gilmore, Elisabeth A. Haas, Brankica Paunovic, Jayaraj Rajagopal, Sara O. Vargas, Robin L. Haynes, Alan Fine, Wellington V. Cardoso, Xingbin Ai
Publikováno v:
Cell Reports, Vol 35, Iss 3, Pp 109011- (2021)
Summary: Pulmonary neuroendocrine cells (PNECs) have crucial roles in airway physiology and immunity by producing bioactive amines and neuropeptides (NPs). A variety of human diseases exhibit PNEC hyperplasia. Given accumulated evidence that PNECs re
Externí odkaz:
https://doaj.org/article/7621fa35a8d64e0f93f6da88caccc9ac
Publikováno v:
Clinical Pharmacology & Therapeutics. 110:69-81
Inflammation of the airway involves the recruitment of highly active immune cells to combat and clear microbes and toxic factors; however, this inflammatory response can result in unintended damage to lung tissue. Tissue damage resulting from inflamm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e744e1ff9bdc7f567b247f04a72b68f5
https://doi.org/10.1002/cpt.2165
https://doi.org/10.1002/cpt.2165
Publikováno v:
The FASEB Journal. 31:4335-4346
Asthma often progresses into adulthood from early-life episodes of adverse environmental exposures. However, how the injury to developing lungs contributes to the pathophysiology of persistent asthma remains poorly understood. In this study, we ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d794e7454878353094e8587ec2c8bf8
https://doi.org/10.1096/fj.201700186r
https://doi.org/10.1096/fj.201700186r
Autor:
Lisa A. Miller, Xingbin Ai, Juliana Barrios, Jin-Ah Park, Kelan G. Tantisira, Linh Aven, Jennifer A. Mitchel, Alvin T. Kho, Scott H. Randell
Publikováno v:
American journal of respiratory cell and molecular biology, vol 60, iss 6
Am J Respir Cell Mol Biol
Am J Respir Cell Mol Biol
Mucus overproduction is a major contributor to morbidity and mortality in asthma. Mucus overproduction is induced by orchestrated actions of multiple factors that include inflammatory cytokines and γ-aminobutyric acid (GABA). GABA is produced only b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36024ad6ae2014d87fdc945a99075fa5
https://escholarship.org/uc/item/6fh5c79z
https://escholarship.org/uc/item/6fh5c79z
Autor:
Alan Fine, Fengzhi Shao, Kenneth G. Trieu, Wei Wang, Xingbin Ai, Jonathan A. Cohen, Juliana Barrios, Yan Bai, Antonia Wallrapp, Vijay K. Kuchroo, Matthew R. Jones, Nandini Krishnamoorthy
Publikováno v:
Immunity. 51(6)
Summary Young children are more susceptible to developing allergic asthma than adults. As neural innervation of the peripheral tissue continues to develop after birth, neurons may modulate tissue inflammation in an age-related manner. Here we showed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faf924740b006d5d29ab2de68c8af895
https://pubmed.ncbi.nlm.nih.gov/31851903
https://pubmed.ncbi.nlm.nih.gov/31851903
Autor:
Michael A. Pazos, Hai Ning Shi, Chien-wen Su, Juliana Barrios, Bryan P. Hurley, Shao Rong Long, Zhong Quan Wang, W. Allan Walker, Bernard B. Lanter, Hongmei Mou
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Intestinal helminth infections elicit Th2-type immunity, which influences host immune responses to additional threats, such as allergens, metabolic disease, and other pathogens. Th2 immunity involves a shift of the CD4+ T-cell population from type-0
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dbd5791bd9a5bb56cb3784b6c44256d
https://pubmed.ncbi.nlm.nih.gov/31673002
https://pubmed.ncbi.nlm.nih.gov/31673002
Autor:
Yan Bai, Kenneth G. Trieu, Juliana Barrios, Matthew R. Jones, Xingbin Ai, Nandini Krishnamoorthy, Wei Wang, Jonathan A. Cohen, Alan Fine
Publikováno v:
SSRN Electronic Journal.
As neural innervation of the peripheral tissue continues to develop after birth, neurons may modulate tissue inflammation in an age-related manner. Herein, we investigated the role of the developing nervous system in the asthma diathesis that charact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be0a09a77ab57d419d17cc9a2fa92fb6
https://doi.org/10.2139/ssrn.3389887
https://doi.org/10.2139/ssrn.3389887
Autor:
Juliana Barrios, Xingbin Ai
Asthma is a chronic airway disease that affects more than 300 million people worldwide. Current treatment focuses on symptomatic relief by temporally dampening inflammation and relaxing the airway. Novel combative strategies against asthma and hopefu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4defa26d9921575dd1e7afa236392053
https://europepmc.org/articles/PMC5931370/
https://europepmc.org/articles/PMC5931370/
E-Cadherin Loss Accelerates Tumor Progression and Metastasis in a Mouse Model of Lung Adenocarcinoma
Autor:
Kerstin W. Sinkevicius, Patrizia Pessina, Roderick T. Bronson, Juliana Barrios, Manav Gupta, Carla F. Kim, Christine Fillmore Brainson, Kelly J. Bellaria
Publikováno v:
American journal of respiratory cell and molecular biology. 59(2)
Metastatic disease is the primary cause of death of patients with lung cancer, but the mouse models of lung adenocarcinoma do not accurately recapitulate the tumor microenvironment or metastatic disease observed in patients. In this study, we conditi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3fa45d0633355367a2d20870fdf98f7
https://pubmed.ncbi.nlm.nih.gov/29447458
https://pubmed.ncbi.nlm.nih.gov/29447458
Autor:
Linh Aven, Rebecca Achey, Martin Minns, Xingbin Ai, Kruti R. Patel, Vickery Trinkaus-Randall, Yoonjoo Lee, Juliana Barrios
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 31(9)
Pulmonary neuroendocrine cells (PNECs) are the only innervated airway epithelial cells. To what extent neural innervation regulates PNEC secretion and function is unknown. Here, we discover that neurotrophin 4 (NT4) plays an essential role in mucus o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c633c6120653a3d9e748ab7ec83cb32
https://pubmed.ncbi.nlm.nih.gov/28566470
https://pubmed.ncbi.nlm.nih.gov/28566470