Výsledky vyhledávání - "Juliana Babu"

Akademický článek

Schizophrenia-associated NRXN1 deletions induce developmental-timing- and cell-type-specific vulnerabilities in human brain organoids

Autor: Rebecca Sebastian, Kang Jin, Narciso Pavon, Ruby Bansal, Andrew Potter, Yoonjae Song, Juliana Babu, Rafael Gabriel, Yubing Sun, Bruce Aronow, ChangHui Pak

Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)

Abstract De novo mutations and copy number deletions in NRXN1 (2p16.3) pose a significant risk for schizophrenia (SCZ). It is unclear how NRXN1 deletions impact cortical development in a cell type-specific manner and disease background modulates thes

Externí odkaz: https://doaj.org/article/e571cbcb7f474cc796ac1dd866a62466

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Schizophrenia-associatedNRXN1deletions induce developmental-timing- and cell-type-specific vulnerabilities in human brain organoids

Autor: Rebecca Sebastian, Kang Jin, Narciso Pavon, Ruby Bansal, Andrew Potter, Yoonjae Song, Juliana Babu, Rafael Gabriel, Yubing Sun, Bruce Aronow, ChangHui Pak

De novomutations and copy number deletions inNRXN1(2p16.3) pose a significant risk for schizophrenia (SCZ). It is unclear howNRXN1deletions impact cortical development in a cell type-specific manner and disease background modulates these phenotypes.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::742bd2d49d80e38fa7c8032c0a4f1603
https://doi.org/10.1101/2022.08.24.505165

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