Cell Death of P. vivax Blood Stages Occurs in Absence of Classical Apoptotic Events and Induces Eryptosis of Parasitized Host Cells

Autor: Carolina Moreira Blanco, Hugo Amorim dos Santos de Souza, Priscilla da Costa Martins, Juliana Almeida-Silva, Ana Marcia Suarez-Fontes, Yury Oliveira Chaves, Marcos André Vannier-Santos, Lilian Rose Pratt-Riccio, Cláudio Tadeu Daniel-Ribeiro, Stefanie Costa Pinto Lopes, Paulo Renato Rivas Totino

Publikováno v: Pathogens, Vol 13, Iss 8, p 673 (2024)

Elucidation of pathways regulating parasite cell death is believed to contribute to identification of novel therapeutic targets for protozoan diseases, and in this context, apoptosis-like cell death has been reported in different groups of protozoa,

Externí odkaz: https://doaj.org/article/adb8c87b143c45f1a14238c95a365b07

'Chagas Express XXI': A new ArtScience social technology for health and science education-A case study in Brazilian endemic areas of Chagas disease with an active search of chronic cases.

Autor: Tania C Araujo-Jorge, Roberto R Ferreira, Rita C M Rocha, Thallyta M Vieira, Nancy D Costa, Luzia L Santos, Josefa O Silva, Marcelo O Mendes, Juliana Almeida-Silva, Erik J Costa, Rodrigo Mexas, Jonathan G Oliveira, Ana M Suarez-Fontes, Teresa C M Gonçalves, Catarina M Lopes, Marcio L Mello, Cristina X A Borges, Luciana R Garzoni, Daniel Gibaldi, Joseli Lannes-Vieira, Marcos A Vannier-Santos

Publikováno v: PLoS Neglected Tropical Diseases, Vol 15, Iss 7, p e0009534 (2021)

BackgroundChagas Disease (CD) affects 6-7 million people worldwide and is related to poverty-promoting conditions. Chronic asymptomatic cases are mostly invisible to health systems. Aiming (1) to translate CD discoveries into education/information pr

Externí odkaz: https://doaj.org/article/f016e683fe3f405798110d0af1a3ee9f

The miRNA 361-3p, a Regulator of GZMB and TNF Is Associated With Therapeutic Failure and Longer Time Healing of Cutaneous Leishmaniasis Caused by L. (viannia) braziliensis

Autor: Tainã S. Lago, Juliana Almeida Silva, Ednaldo L. Lago, Edgar M. Carvalho, Dalila L. Zanette, Léa Cristina Castellucci

Publikováno v: Frontiers in Immunology, Vol 9 (2018)

L. (viannia) braziliensis infection causes American Tegumentary Leishmaniasis (ATL), with prolonged time to healing lesions. The potent inflammatory response developed by the host is important to control the parasite burden and infection however an u

Externí odkaz: https://doaj.org/article/4e09b6e11b404a47b84599d002ec6bfd

Translational Research on Chagas Disease: Focusing on Drug Combination and Repositioning

Autor: André, Vannier-Santos, Marcos, Márcia, Suarez-Fontes, Ana, Juliana, Almeida-Silva, Lifsitch, Viçosa, Alessandra, Chavez, Perez, Sandra Aurora, Marcel, Hasslocher-Moreno, Alejandro, Estolano, da Silveira, Gabriel Parreiras, Fernandes, Portela, Luciana, Magalhães, Saraiva, Roberto

Publikováno v: Chagas Disease-From Cellular and Molecular Aspects of Trypanosoma cruzi-Host Interactions to the Clinical Intervention

Chagas disease, caused by the protozoan Trypanosoma cruzi, is a major neglected disease endemic to Latin America, associated to significant morbimortality comprising a remarkable socioeconomic problem mainly for low-income tropical populations. The p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db618a478402b4b5d97dd603ec1911dc
https://doi.org/10.5772/intechopen.104231

Cellular infiltrate in cutaneous leishmaniasis lesions and therapeutic outcome

Autor: Silvia R. B. Uliana, Riam Rocha França, Juliana Almeida Silva, Paulo R.L. Machado, Silvana C. Silva, Viviane Boaventura, Camila Sampaio Ribeiro

Publikováno v: Anais Brasileiros de Dermatologia v.96 n.5 2021
Anais brasileiros de dermatologia
Sociedade Brasileira de Dermatologia (SBD)
instacron:SBD
Anais Brasileiros de Dermatologia
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Anais Brasileiros de Dermatologia, Vol 96, Iss 5, Pp 544-550 (2021)
Anais Brasileiros de Dermatologia, Volume: 96, Issue: 5, Pages: 544-550, Published: 18 OCT 2021

Background The treatment of cutaneous leishmaniasis is a challenge. A better understanding of the in situ mechanisms involved in the evolution and cure of the disease is essential for the development of new therapies. Objective Correlate histopatholo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8f873b929c518b16d9344ff41c04b93
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962021000500544