Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Juliana Akinaga"'
Publikováno v:
Pharmacology Research & Perspectives, Vol 10, Iss 5, Pp n/a-n/a (2022)
Abstract α2‐adrenoceptors, (α2A, α2B and α2C‐subtypes), are Gi‐coupled receptors. Central activation of brain α2A and α2C‐adrenoceptors is the main site for α2‐agonist mediated clinical responses in hypertension, ADHD, muscle spasm a
Externí odkaz:
https://doaj.org/article/62f574fc49f84753a64d6f5b7905307a
Publikováno v:
Pharmacology Research & Perspectives, Vol 10, Iss 2, Pp n/a-n/a (2022)
Abstract α2‐Adrenoceptors, subdivided into α2A, α2B, and α2C subtypes and expressed in heart, blood vessels, kidney, platelets and brain, are important for blood pressure, sedation, analgesia, and platelet aggregation. Brain α2C‐adrenoceptor
Externí odkaz:
https://doaj.org/article/4748e39534774fa8b107ecb93e50747a
Publikováno v:
British Journal of Pharmacology.
α1 -Adrenoceptors are seven transmembrane domain GPCRs involved in numerous physiological functions controlled by the endogenous catecholamines, noradrenaline and adrenaline, and targeted by drugs useful in therapeutics. Three separate genes, whose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dda40ed035e150085ad29a5087c7db7f
https://doi.org/10.1111/bph.14617
https://doi.org/10.1111/bph.14617
Publikováno v:
Br J Pharmacol
α(1)‐Adrenoceptors are seven transmembrane domain GPCRs involved in numerous physiological functions controlled by the endogenous catecholamines, noradrenaline and adrenaline, and targeted by drugs useful in therapeutics. Three separate genes, who
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ca0ca4a2ded08ee3a832781a34d7966f
https://pubmed.ncbi.nlm.nih.gov/30740663
https://pubmed.ncbi.nlm.nih.gov/30740663
Autor:
Natalia Lautherbach, Patricia de Oliveira Benedet, Marcos A. Rossi, Daniela Dal-Secco, Jamil Assreuy, Vanessa Lima, André S. Pupo, Mara Rúbia Nunes Celes, Juliana Akinaga, Adriana H. Souza, Katiussia Pinho da Silva, Fernando Q. Cunha, Silvia DalBó, F. N. Gava, Isis do Carmo Kettelhut, Luiz Ricardo de Almeida Kiguti
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
G protein-coupled receptor kinase isoform 2 (GRK2) has a critical role in physiological and pharmacological responses to endogenous and exogenous substances. Sepsis causes an important cardiovascular dysfunction in which nitric oxide (NO) has a relev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8368aef4e76078997565c3b5a032ff5
Autor:
Fernanda D. Nojimoto, Juliana Akinaga, Vanessa Lima, L.R.de A. Kiguti, Andre Mueller, André S. Pupo, Flavia Hebeler-Barbosa
Publikováno v:
Neuropharmacology. 59:49-57
Although it is long known that the tricyclic antidepressants amitriptyline, nortriptyline and imipramine inhibit the noradrenaline transporter and alpha(1)-adrenoceptors with similar affinities, which may lead to self-cancelling actions, the selectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::412376e989d12df11089e7354a276a96
https://doi.org/10.1016/j.neuropharm.2010.03.015
https://doi.org/10.1016/j.neuropharm.2010.03.015
Autor:
Luiz Ricardo de Almeida Kiguti, Vanessa Lima, André S. Pupo, Flavia Hebeler-Barbosa, Rocio J. Alcántara-Hernández, Juliana Akinaga, J. Adolfo García-Sáinz
Publikováno v:
Molecular pharmacology. 83(4)
Loss of response on repetitive drug exposure (i.e., tachyphylaxis) is a particular problem for the vasoconstrictor effects of medications containing oxymetazoline (OXY), an α1-adrenoceptor (AR) agonist of the imidazoline class. One cause of tachyphy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae86f31e56fa1ac7e68a40bb1e8df5bb
https://pubmed.ncbi.nlm.nih.gov/23364786
https://pubmed.ncbi.nlm.nih.gov/23364786
Autor:
Andre Mueller, Anthony C. S. Castilho, Vanessa Lima, Juliana Akinaga, Jose Buratini, Fernanda D. Nojimoto, André S. Pupo, Susana Y. Kamikihara
Publikováno v:
Naunyn-Schmiedeberg's archives of pharmacology. 376(1-2)
It has been recently shown that the supersensitivity of distal segments of the rat tail artery to phenylephrine after chemical sympathectomy with reserpine results from the appearance of alpha(1D)-adrenoceptors. It is known that both alpha(1A)- and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb733fdd8eb41eb1b0fb9faac67d8f2d
https://pubmed.ncbi.nlm.nih.gov/17676312
https://pubmed.ncbi.nlm.nih.gov/17676312