Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Julian Wampfler"'
Publikováno v:
Swiss Medical Weekly, Vol 154, Iss 4 (2024)
BACKGROUND AND AIMS OF THE STUDY: Due to its importance for treatment and potential prevention in family members, germline testing for BRCA1/2 in patients with newly diagnosed ovarian cancer is decisive and considered a standard of care. Maintenance
Externí odkaz:
https://doaj.org/article/315168d36568476badcec7d3072e7ad0
Autor:
Saira Khalique, Sarah Nash, David Mansfield, Julian Wampfler, Ayoma Attygale, Katherine Vroobel, Harriet Kemp, Richard Buus, Hannah Cottom, Ioannis Roxanis, Thomas Jones, Katharina von Loga, Dipa Begum, Naomi Guppy, Pradeep Ramagiri, Kerry Fenwick, Nik Matthews, Michael J. F. Hubank, Christopher J. Lord, Syed Haider, Alan Melcher, Susana Banerjee, Rachael Natrajan
Publikováno v:
Cancers, Vol 13, Iss 15, p 3854 (2021)
Ovarian clear cell carcinoma (OCCC) is a rare subtype of epithelial ovarian cancer characterised by a high frequency of loss-of-function ARID1A mutations and a poor response to chemotherapy. Despite their generally low mutational burden, an intratumo
Externí odkaz:
https://doaj.org/article/4572fce1c8e0454eb8e4726155bb806e
Autor:
Murielle N. Wahli, Stefanie Hayoz, Dennis Hoch, Christoph O. Ryser, Michèle Hoffmann, Amina Scherz, Birgit Schwacha-Eipper, Simon Häfliger, Julian Wampfler, Martin D. Berger, Urban Novak, Berna C. Özdemir
Publikováno v:
Wahli, Murielle N; Hayoz, Stefanie; Hoch, Dennis; Ryser, Christoph O; Hoffmann, Michèle; Scherz, Amina; Schwacha-Eipper, Birgit; Häfliger, Simon; Wampfler, Julian; Berger, Martin D; Novak, Urban; Özdemir, Berna C (2023). The role of immune checkpoint inhibitors in clinical practice: an analysis of the treatment patterns, survival and toxicity rates by sex. Journal of cancer research and clinical oncology, 149(7), pp. 3847-3858. Springer 10.1007/s00432-022-04309-2
Purpose Our aim is to describe the role of immune checkpoint inhibitors (ICI) in clinical practice by providing the patient and tumor characteristics as well as survival and toxicity rates by sex. Methods We used electronic health records to identify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f73ec8da3061d50b4a5d30ba44729160
Publikováno v:
Journal of Leukocyte Biology. 98:357-363
Successful myeloid differentiation depends on the expression of a series of miRNAs. Thus, it is hardly surprising that miRNAs are globally repressed in AML, a disease mainly characterized by a block in cellular myeloid differentiation. Studies invest
Publikováno v:
Leukemia research. 41
The RNA binding proteins RBM binding motif protein 38 (RBM38) and DEAD END 1 (DND1) selectively stabilize mRNAs by attenuating RNAse activity or protecting them from micro(mi)RNA-mediated cleavage. Furthermore, both proteins can efficiently stabilize