Long lasting response to anti-PD-1 therapy of recurrent conjunctival squamous cell carcinoma - A case report and systematic review of the literature

Autor: Michèle Hoffmann, Julian Schardt, Codruta Ionescu, Ute E. Wolf-Schnurrbusch, Franca Wagner, Matthias S. Dettmer, Radu Olariu, Berna C. Özdemir

Publikováno v: Current Problems in Cancer: Case Reports, Vol 4, Iss , Pp 100088- (2021)

Background: Squamous cell carcinoma (SCC) are slowly progressing tumors which represent the most common malignancy of the ocular surface. The standard of care is surgical excision with wide margins combined with intra-operative cryotherapy. In advanc

Externí odkaz: https://doaj.org/article/ea997adae74a4fc7bcecfcf06759aba2

Adding bendamustine to melphalan before ASCT improves CR rate in myeloma vs. melphalan alone: A randomized phase-2 trial

Autor: Sarah Farag, Ulrike Bacher, Barbara Jeker, Myriam Legros, Gaelle Rhyner, Jean-Marc Lüthi, Julian Schardt, Thilo Zander, Michael Daskalakis, Behrouz Mansouri, Chantal Manz, Thomas Pabst

Publikováno v: Farag, Sarah; Bacher, Ulrike; Jeker, Barbara; Legros, Myriam; Rhyner, Gaelle; Lüthi, Jean-Marc; Schardt, Julian; Zander, Thilo; Daskalakis, Michael; Mansouri, Behrouz; Manz, Chantal; Pabst, Thomas (2022). Adding bendamustine to melphalan before ASCT improves CR rate in myeloma vs. melphalan alone: A randomized phase-2 trial. Bone marrow transplantation, 57(6), pp. 990-997. Springer Nature 10.1038/s41409-022-01681-y

Definite cure remains exceptional in myeloma patients even after high-dose chemotherapy (HDCT) with melphalan (Mel) and autologous stem cell transplantation (ASCT). Thus, improving efficacy of HDCT in MM remains an unresolved issue. This randomized p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b174f7bb47dbd42fce5c9a78ce47ed0
https://boris.unibe.ch/169441/1/s41409-022-01681-y.pdf

Immuntherapie – Übersicht, Wirkmechanismen, Anwendung

Autor: Julian Schardt, Ruben Bill

Publikováno v: Therapeutische Umschau. 76:187-194

Zusammenfassung. Die Entwicklung von neuen Immuntherapien hat die Behandlungskonzepte von unterschiedlichen Krebsarten aus der Reihe der soliden Tumoren bis hin zu hämatologischen Krebserkrankungen in den letzten Jahren revolutioniert. Dabei werden

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dff39ddaa7f013c22726ff1e86eb1c1b
https://doi.org/10.1024/0040-5930/a001083

[The use of immune checkpoint inhibitors in routine oncology]

Autor: Julian, Schardt

Publikováno v: Zeitschrift Fur Rheumatologie

The advent of immune checkpoint inhibitors has dramatically changed the treatment landscape of many different tumor types. In the clinical routine, humanized antibodies against the immune checkpoints cytotoxic T‑lymphocyte associated protein 4 (CTL

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::06d45e2ff5e6722f976b12c9e1bb986e
https://pubmed.ncbi.nlm.nih.gov/32936368

Long lasting response to anti-PD-1 therapy of recurrent conjunctival squamous cell carcinoma - A case report and systematic review of the literature

Autor: Codruta Ionescu, Ute E. K. Wolf-Schnurrbusch, Berna C. Özdemir, Matthias S. Dettmer, Michèle Hoffmann, Franca Wagner, Julian Schardt, Radu Olariu

Publikováno v: Hoffmann, Michèle; Schardt, Julian; Ionescu, Codruta; Wolf-Schnurrbusch, Ute E.; Wagner, Franca; Dettmer, Matthias S.; Olariu, Radu; Özdemir, Berna C. (2021). Long lasting response to anti-PD-1 therapy of recurrent conjunctival squamous cell carcinoma-A case report and systematic review of the literature. Current problems in cancer: case reports, 4, p. 100088. Elsevier 10.1016/j.cpccr.2021.100088
Current Problems in Cancer: Case Reports, Vol 4, Iss, Pp 100088-(2021)

Background Squamous cell carcinoma (SCC) are slowly progressing tumors which represent the most common malignancy of the ocular surface. The standard of care is surgical excision with wide margins combined with intra-operative cryotherapy. In advance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6709ac06e7958f16c7dd8658fdbe997e
https://doi.org/10.1016/j.cpccr.2021.100088