Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Julian S. Rechberger"'
Autor:
Leo F. Nonnenbroich, Samantha M. Bouchal, Elena Millesi, Julian S. Rechberger, Soumen Khatua, David J. Daniels
Publikováno v:
Cells, Vol 13, Iss 13, p 1122 (2024)
Pediatric high-grade gliomas are a devastating subset of brain tumors, characterized by their aggressive pathophysiology and limited treatment options. Among them, H3 K27-altered diffuse midline gliomas (DMG) of the brainstem stand out due to their d
Externí odkaz:
https://doaj.org/article/3f4718bfa8164e4bac71b09daec89eec
Autor:
Jawad Fares, Zachary B. Davis, Julian S. Rechberger, Stephanie A. Toll, Jonathan D. Schwartz, David J. Daniels, Jeffrey S. Miller, Soumen Khatua
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-17 (2023)
Abstract Despite advances in treatment regimens that comprise surgery, chemotherapy, and radiation, outcome of many brain tumors remains dismal, more so when they recur. The proximity of brain tumors to delicate neural structures often precludes comp
Externí odkaz:
https://doaj.org/article/4a6a001808714a25aa0164406a5ed579
Autor:
Karolina I. Pellot Ortiz, Julian S. Rechberger, Leo F. Nonnenbroich, David J. Daniels, Jann N. Sarkaria
Publikováno v:
Biomedicines, Vol 11, Iss 7, p 1879 (2023)
Inhibition of the interaction between MDM2 and p53 has emerged as a promising strategy for combating cancer, including the treatment of glioblastoma (GBM). Numerous MDM2 inhibitors have been developed and are currently undergoing rigorous testing for
Externí odkaz:
https://doaj.org/article/4689544e1d0b4748967b990b077dd65d
Autor:
Julian S. Rechberger, Stephanie A. Toll, Wouter J. F. Vanbilloen, David J. Daniels, Soumen Khatua
Publikováno v:
Diagnostics, Vol 13, Iss 14, p 2398 (2023)
Medulloblastoma is the most common malignant brain tumor in children. Over the last few decades, significant progress has been made in revealing the key molecular underpinnings of this disease, leading to the identification of distinct molecular subg
Externí odkaz:
https://doaj.org/article/2ef62a7f3da449c1878c2e8c336bde6a
Autor:
Wouter J. F. Vanbilloen, Julian S. Rechberger, Jacob B. Anderson, Leo F. Nonnenbroich, Liang Zhang, David J. Daniels
Publikováno v:
Pharmaceutics, Vol 15, Iss 7, p 1804 (2023)
Primary brain and central nervous system (CNS) tumors are a diverse group of neoplasms that occur within the brain and spinal cord. Although significant advances in our understanding of the intricate biological underpinnings of CNS neoplasm tumorigen
Externí odkaz:
https://doaj.org/article/6afe75902ecc4eed882596974fd76cc2
Autor:
Julian S. Rechberger, Kendra A. Porath, Liang Zhang, Cody L. Nesvick, Randy S. Schrecengost, Jann N. Sarkaria, David J. Daniels
Publikováno v:
Pharmaceutics, Vol 14, Iss 5, p 922 (2022)
High-grade gliomas (HGG) are devastating diseases in children and adults. In the pediatric population, diffuse midline gliomas (DMG) harboring H3K27 alterations are the most aggressive primary malignant brain tumors. With no effective therapies avail
Externí odkaz:
https://doaj.org/article/76a1b632f4d249bc948beb51d4af6122
Publikováno v:
Pharmaceutics, Vol 13, Iss 11, p 1885 (2021)
Intra-arterial drug delivery circumvents the first-pass effect and is believed to increase both efficacy and tolerability of primary and metastatic brain tumor therapy. The aim of this update is to report on pertinent articles and clinical trials to
Externí odkaz:
https://doaj.org/article/4e4a8c5b19bf4841b7947a7a716eb304
Publikováno v:
Expert Opinion on Therapeutic Targets. 27:9-17
Publikováno v:
Therapeutic Delivery. 13:1-4
Graphical abstract [Formula: see text]
Autor:
Danielle D. Dang, Julian S. Rechberger, Luciano C. Leonel, Michael J. Link, David J. Daniels, Maria Peris-Celda
Publikováno v:
32nd Annual Meeting North American Skull Base Society.