Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Julian Ramos"'
Targeting a therapeutic LIF transgene to muscle via the immune system ameliorates muscular dystrophy
Autor:
Steven S. Welc, Ivan Flores, Michelle Wehling-Henricks, Julian Ramos, Ying Wang, Carmen Bertoni, James G. Tidball
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
A number of therapeutic agents aimed at reducing pathology in Duchenne muscular dystrophy have been developed, but may have off-target effects when delivered systemically. Here, the authors express the therapeutic LIF transgene in leukocytes, and sho
Externí odkaz:
https://doaj.org/article/264ed254b4494b4a8400489886319488
Autor:
Ruben Delgado-Escano, Francisco M. Castro, Julian Ramos Cozar, Manuel J. Marin-Jimenez, Nicolas Guil
Publikováno v:
IEEE Access, Vol 7, Pp 1897-1908 (2019)
People identification using gait information (i.e., the way a person walks) obtained from inertial sensors is a robust approach that can be used in multiple situations where vision-based systems are not applicable. Typically, previous methods use han
Externí odkaz:
https://doaj.org/article/62683e77efbe4350b562b75079af9854
Autor:
Chady H. Hakim, Nalinda B. Wasala, Xiufang Pan, Kasun Kodippili, Yongping Yue, Keqing Zhang, Gang Yao, Brittney Haffner, Sean X. Duan, Julian Ramos, Joel S. Schneider, N. Nora Yang, Jeffrey S. Chamberlain, Dongsheng Duan
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 6, Iss C, Pp 216-230 (2017)
Micro-dystrophins are highly promising candidates for treating Duchenne muscular dystrophy, a lethal muscle disease caused by dystrophin deficiency. Here, we report robust disease rescue in the severe DBA/2J-mdx model with a neuronal nitric oxide syn
Externí odkaz:
https://doaj.org/article/a968d82e3a484f8cb6cd48ebc8ad7bec
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Acta Geophysica. 69:1287-1296
The Santa Lucia River Basin Trough is located in the southern sector of the Eastern Republic of Uruguay and has an area of almost 6,000 km2. In this work, the depth to the basement in the SW sector of the Santa Lucia Basin (SLB) was determined, using
Autor:
Ruber Hernandez-Garcia, Zheng Feng, Ricardo J. Barrientos, Francisco Manuel Castro, Julian Ramos-Cozar, Nicolas Guil
Publikováno v:
2022 12th International Conference on Pattern Recognition Systems (ICPRS).
Autor:
Ruber Hernandez-Garcia, Jose I. Santamaria, Ricardo J. Barrientos, Edwin H. Salazar Jurado, Francisco Manuel Castro, Julian Ramos-Cozar, Nicolas Guil
Publikováno v:
2021 40th International Conference of the Chilean Computer Science Society (SCCC).
Autor:
Jose I. Santamaria, Ruber Hernandez-Garcia, Ricardo J. Barrientos, Francisco Manuel Castro, Julian Ramos-Cozar, Nicolas Guil
Publikováno v:
2021 40th International Conference of the Chilean Computer Science Society (SCCC).
Targeting a therapeutic LIF transgene to muscle via the immune system ameliorates muscular dystrophy
Autor:
Michelle Wehling-Henricks, Julian Ramos, James G. Tidball, Ying Wang, Carmen Bertoni, Steven S. Welc, Ivan Flores
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Nature Communications
Nature communications, vol 10, iss 1
Nature Communications
Nature communications, vol 10, iss 1
Many potentially therapeutic molecules have been identified for treating Duchenne muscular dystrophy. However, targeting those molecules only to sites of active pathology is an obstacle to their clinical use. Because dystrophic muscles become extensi
Autor:
Julian Ramos, James M. Allen, Jeffrey S. Chamberlain, Niclas E. Bengtsson, Stephen D. Hauschka, Katrin Hollinger
Publikováno v:
Molecular Therapy. 27:623-635
Gene therapies using adeno-associated viral (AAV) vectors have advanced into clinical trials for several diseases, including Duchenne muscular dystrophy (DMD). A limitation of AAV is the carrying capacity (∼5 kb) available for genes and regulatory