Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Julian R Buissant des Amorie"'
Autor:
Yannik Bollen, Joris H Hageman, Petra van Leenen, Lucca L M Derks, Bas Ponsioen, Julian R Buissant des Amorie, Ingrid Verlaan-Klink, Myrna van den Bos, Leon W M M Terstappen, Ruben van Boxtel, Hugo J G Snippert
Publikováno v:
PLoS Biology, Vol 20, Iss 1, p e3001527 (2022)
CRISPR-associated nucleases are powerful tools for precise genome editing of model systems, including human organoids. Current methods describing fluorescent gene tagging in organoids rely on the generation of DNA double-strand breaks (DSBs) to stimu
Externí odkaz:
https://doaj.org/article/cd66eca306e549c4a4b1983de5881ebb
Autor:
Livio Trusolino, Francesco Sassi, Sander Mertens, Benjamin Cappe, Ingrid Verlaan-Klink, Ravian L. van Ineveld, Bas Ponsioen, Sylvia F. Boj, Simone Kersten, Julian R. Buissant des Amorie, Dimitrios Laskaris, Rob G. J. Vries, Franck B. Riquet, Andrea Bertotti, Jasmin B. Post, François Sipieter, Johannes L. Bos, Peter Vandenabeele, Hugo J. Snippert, Holger Rehmann
Publikováno v:
Nature cell biology
Nature Cell Biology
Nature Cell Biology, Nature Publishing Group, 2021, 23 (4), pp.377-390. ⟨10.1038/s41556-021-00654-5⟩
Nature Cell Biology
Nature Cell Biology, Nature Publishing Group, 2021, 23 (4), pp.377-390. ⟨10.1038/s41556-021-00654-5⟩
Direct targeting of the downstream mitogen-activated protein kinase (MAPK) pathway to suppress extracellular-regulated kinase (ERK) activation in KRAS and BRAF mutant colorectal cancer (CRC) has proven clinically unsuccessful, but promising results h