Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Julian Quodbach"'
Publikováno v:
International Journal of Pharmaceutics: X, Vol 8, Iss , Pp 100277- (2024)
Pharmacies are currently unable to stock proper oral dosage forms for pediatric populations. This leads to manipulation of medications or the need to compound specialized medications, which can be a time-consuming process. Using Semisolid Extrusion (
Externí odkaz:
https://doaj.org/article/86826b6e071d4dc2874391519d234feb
Publikováno v:
International Journal of Pharmaceutics: X, Vol 7, Iss , Pp 100256- (2024)
The field of pharmaceutical 3D printing is growing over the past year, with Spitam® as the first 3D printed dosage form on the market. Showing the suitability of a binder jetting process for dosage forms. Although the development of inks for pharmac
Externí odkaz:
https://doaj.org/article/37c1ef09e3024d5bac3622b6f091cf5e
Publikováno v:
Frontiers in Drug Delivery, Vol 4 (2024)
Selective Laser Sintering (SLS) has the potential to offer a more accurate alternative to current-practice manipulation of oral dosage forms for pediatric, geriatric, and dysphagia-suffering patient groups. In order to create the best possible dosage
Externí odkaz:
https://doaj.org/article/fb6f040665454cd4aeb5f16ee990950d
Publikováno v:
International Journal of Pharmaceutics: X, Vol 5, Iss , Pp 100179- (2023)
Nowadays, a high number of pipeline drugs are poorly soluble and require solubility enhancement by e.g., manufacturing of amorphous solid dispersion. Pharmaceutical 3D printing has great potential in producing amorphous solid oral dosage forms. Howev
Externí odkaz:
https://doaj.org/article/09cd32e2a0544c71ac431438cb44475c
Publikováno v:
International Journal of Pharmaceutics: X, Vol 5, Iss , Pp 100151- (2023)
Drop-on-powder 3D printing is able to produce highly drug loaded solid oral dosage forms. However, this technique is mainly limited to well soluble drugs. The majority of pipeline compounds is poorly soluble, though, and requires solubility enhanceme
Externí odkaz:
https://doaj.org/article/53c740fbdfca43c39ad4d680248942c5
Autor:
Anna Karagianni, Julian Quodbach, Oliver Weingart, Anastasia Tsiaxerli, Vasiliki Katsanou, Vera Vasylyeva, Christoph Janiak, Kyriakos Kachrimanis
Publikováno v:
Solids, Vol 3, Iss 1, Pp 66-92 (2022)
Pharmaceutical cocrystals are currently gaining interest among the scientific community, due to their great potential for providing novel crystalline forms with superior properties such as solubility, dissolution rate, bioavailability, and stability.
Externí odkaz:
https://doaj.org/article/f2d17b25465f47bdb39605e54f97c6f2
Autor:
Hanna Ponsar, Julian Quodbach
Publikováno v:
Pharmaceutics, Vol 15, Iss 8, p 2097 (2023)
Three-dimensional-printed customizable drug-loaded implants provide promising opportunities to improve the current therapy options. In this study, we present a modular implant in which shape, dosage, and drug release can be individualized independent
Externí odkaz:
https://doaj.org/article/6cdf177c462248a38063a7bd551d7c7d
Publikováno v:
Pharmaceutics, Vol 14, Iss 11, p 2411 (2022)
Fused deposition modeling (FDM) 3D printing was used to produce 3D printed tablets with the thermo-sensitive model peptidomimetic drug enalapril maleate (EM). Two different formulations were prepared to investigate the degradation of enalapril maleat
Externí odkaz:
https://doaj.org/article/ad61fbad97564100843b3fc5ecc21391
Publikováno v:
Pharmaceutics, Vol 14, Iss 10, p 2091 (2022)
The aim of this research was the production of extrudates for the treatment of hypertension and heart failure and the investigation of the degradation of the peptidomimetic drug enalapril maleate (EM) during hot-melt extrusion (HME). A fast HPLC meth
Externí odkaz:
https://doaj.org/article/5ecb29a5f1b345a3ad0e678eb64c6491
Publikováno v:
Pharmaceutics, Vol 14, Iss 5, p 931 (2022)
Therapy for Parkinson’s disease is quite challenging. Numerous drugs are available for symptomatic treatment, and levodopa (LD), in combination with a dopa decarboxylase inhibitor (e.g., benserazide (BZ)), has been the drug of choice for years. As
Externí odkaz:
https://doaj.org/article/a743e5e4d30b4945ac65bb74f3fb2a07