Bacterial cell cycle control by citrate synthase independent of enzymatic activity

Autor: Matthieu Bergé, Julian Pezzatti, Víctor González-Ruiz, Laurence Degeorges, Geneviève Mottet-Osman, Serge Rudaz, Patrick H Viollier

Publikováno v: eLife, Vol 9 (2020)

Proliferating cells must coordinate central metabolism with the cell cycle. How central energy metabolism regulates bacterial cell cycle functions is not well understood. Our forward genetic selection unearthed the Krebs cycle enzyme citrate synthase

Externí odkaz: https://doaj.org/article/3e15b3a7bc6a4dfc99b5b06c3dc32ec5

Choosing an Optimal Sample Preparation in Caulobacter crescentus for Untargeted Metabolomics Approaches

Autor: Julian Pezzatti, Matthieu Bergé, Julien Boccard, Santiago Codesido, Yoric Gagnebin, Patrick H. Viollier, Víctor González-Ruiz, Serge Rudaz

Publikováno v: Metabolites, Vol 9, Iss 10, p 193 (2019)

Untargeted metabolomics aims to provide a global picture of the metabolites present in the system under study. To this end, making a careful choice of sample preparation is mandatory to obtain reliable and reproducible biological information. In this

Externí odkaz: https://doaj.org/article/47e64be30c054523b42e63eee48d9a36

Combining the advantages of multilevel and orthogonal partial least squares data analysis for longitudinal metabolomics: Application to kidney transplantation

Autor: Yoric Gagnebin, Pierre Lescuyer, Julian Pezzatti, Julien Boccard, Belen Ponte, Serge Rudaz

Publikováno v: Analytica Chimica Acta, Vol. 1099 (2020) pp. 26-38

Kidney transplantation is one of the renal replacement options in patients suffering from end-stage renal disease (ESRD). After a transplant, patient follow-up is essential and is mostly based on immunosuppressive drug levels control, creatinine meas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13d09b3f0c2ab246ece32ebbcd0d3470
https://doi.org/10.1016/j.aca.2019.11.050

Interlaboratory and Interplatform Study of Steroids Collision Cross Section by Traveling Wave Ion Mobility Spectrometry

Autor: Evelyne Vigneau, Bruno Le Bizec, Serge Rudaz, Davy Guillarme, David Ropartz, Maykel Hernández-Mesa, Mathieu Fanuel, Hélène Rogniaux, Nicola Dreolin, Fabrice Monteau, Julian Pezzatti, Valentina D'Atri, Sara Stead, Gaud Dervilly, Gitte Barknowitz

Publikováno v: Analytical Chemistry
Analytical Chemistry, American Chemical Society, 2020, 92 (7), pp.5013-5022. ⟨10.1021/acs.analchem.9b05247⟩
Analytical Chemistry, Vol. 92, No 7 (2020) pp. 5013-5022

International audience; Collision cross section (CCS) databases based on single-laboratory measurements must be cross-validated to extend their use in peak annotation. This work addresses the validation of the first comprehensive TWCCSN2 database for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bbff5fb4d8e91bec6f2e3895d6548df
https://hal.inrae.fr/hal-03191081

Implementation of liquid chromatography–high resolution mass spectrometry methods for untargeted metabolomic analyses of biological samples: A tutorial

Autor: Santiago Codesido, Julien Boccard, Yoric Gagnebin, Julian Pezzatti, Didier Picard, Víctor González-Ruiz, Abhinav Joshi, Serge Rudaz

Publikováno v: Analytica Chimica Acta, Vol. 1105 (2020) pp. 28-44

Untargeted metabolomics is now widely recognized as a useful tool for exploring metabolic changes taking place in biological systems under different conditions. By its nature, this is a highly interdisciplinary field of research, and mastering all of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5410a8250147544cbaade558c27aee7
https://archive-ouverte.unige.ch/unige:133086