Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Julian P Tuazon"'
Autor:
Yuyang Zhang, Seongjin Yu, Julian P Tuazon, Jea-Young Lee, Sydney Corey, Lauren Kvederis, Chase Kingsbury, Yuji Kaneko, Cesar V Borlongan
Publikováno v:
Neural Regeneration Research, Vol 14, Iss 4, Pp 597-604 (2019)
Transplantation of human bone marrow mesenchymal stem cells (hMSCs) stands as a potent stroke therapy, but its exact mechanism remains unknown. This study investigated the anti-apoptotic mechanisms by which hMSCs exert neuroprotective effects on cere
Externí odkaz:
https://doaj.org/article/1d3eedd8cbff4d82848a51f0b1d41516
Publikováno v:
Neural Regeneration Research, Vol 13, Iss 12, Pp 2029-2037 (2018)
Neurovascular disorders, such as traumatic brain injury and stroke, persist as leading causes of death and disability – thus, the search for novel therapeutic approaches for these disorders continues. Many hurdles have hindered the translation of e
Externí odkaz:
https://doaj.org/article/9290a1a97076454b8c0c81d99a68563a
Publikováno v:
Brain Circulation, Vol 4, Iss 3, Pp 81-83 (2018)
Externí odkaz:
https://doaj.org/article/303532dbee954293bca6ede254cd37a0
Autor:
Yuji Kaneko, Jea‐Young Lee, Naoki Tajiri, Julian P. Tuazon, Trenton Lippert, Eleonora Russo, Seong‐Jin Yu, Brooke Bonsack, Sydney Corey, Alexandreya B. Coats, Chase Kingsbury, Thomas N. Chase, Minako Koga, Cesar V. Borlongan
Publikováno v:
Stem Cells Translational Medicine, Vol 9, Iss 2, Pp 203-220 (2020)
Abstract The present study used in vitro and in vivo stroke models to demonstrate the safety, efficacy, and mechanism of action of adult human bone marrow‐derived NCS‐01 cells. Coculture with NCS‐01 cells protected primary rat cortical cells or
Externí odkaz:
https://doaj.org/article/fde3b4a51a0044ce98994e0e757c6a16
Publikováno v:
Cell Transplantation, Vol 28 (2019)
Myocardial infarction (MI) is the leading cause of morbidity and mortality in the world. The infarcted heart displays typical cell death cascades characterized by a loss of cells and fibrotic scarring in the myocardium. Cardiac hypertrophy and fibros
Externí odkaz:
https://doaj.org/article/6b7c7b8c077941f5af531f351e6282e5
Autor:
Kaya Xu, Jea-Young Lee, Yuji Kaneko, Julian P. Tuazon, Fernando Vale, Harry van Loveren, Cesario V. Borlongan
Publikováno v:
Haematologica, Vol 104, Iss 5 (2019)
Despite mounting evidence of a massive peripheral inflammatory response accompanying stroke, the ability of intracerebrally transplanted cells to migrate to the periphery and sequester systemic inflammation remains unexamined. Here, we tested the hyp
Externí odkaz:
https://doaj.org/article/1032c3129c35491aa71e7d448af7a85c
Autor:
Jea-Young Lee, Julian P. Tuazon, Sydney Corey, Brooke Bonsack, Sandra Acosta, Jared Ehrhart, Paul R. Sanberg, Cesario V. Borlongan
Publikováno v:
Stem Cell Reviews and Reports. 18:2203-2205
Publikováno v:
Expert Opin Drug Deliv
INTRODUCTION: Stem cell therapy is an experimental treatment for brain disorders. Although a cellular product, stem cells can be classified as biologics based on the cells’ secretion of therapeutic substances. Treatment with stem cell biologics may
Autor:
Julian P. Tuazon, Yuji Kaneko, Sydney Zarriello, Hiroto Ishikawa, Paul R. Sanberg, Naoki Tajiri, Jea-Young Lee, Cesario V. Borlongan, Sydney Corey, Kazutaka Shinozuka
Publikováno v:
J Cereb Blood Flow Metab
Rodents display “empathy” defined as perceived physical pain or psychological stress by cagemates when co-experiencing socially distinct traumatic events. The present study tested the hypothesis that empathy occurs in adult rats subjected to an e
Publikováno v:
Journal of Cellular and Molecular Medicine
Current therapies for Parkinson's disease (PD), including L‐3,4‐dihydroxyphenylalanine (L‐DOPA), and clinical trials investigating dopaminergic cell transplants, have generated mixed results with the eventual induction of dyskinetic side effect