Výsledky vyhledávání - "Julian Norman Kenyon"

Trypsinogen and chymotrypsinogen: potent anti-tumor agents

Autor: Shivan Barungi, Macarena Perán, Pablo Hernández-Camarero, Julian Norman Kenyon, Aitor González-Titos, Juan A. Marchal

Publikováno v: Expert opinion on biological therapy. 21(12)

Introduction: Trypsinogen and chymotrypsinogen have been used clinically in tissue repair due to their ability to resolve inflammatory symptoms. Recently, novel evidence has supported the anti-tumo...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ceb64372d8ee8f7fa3478213a606554
https://pubmed.ncbi.nlm.nih.gov/33896307

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Pancreatic (pro)enzymes treatment suppresses BXPC-3 pancreatic Cancer Stem Cell subpopulation and impairs tumour engrafting

Autor: Elena López-Ruiz, Macarena Perán, Julian Norman Kenyon, Carlos Chocarro-Wrona, Juan A. Marchal, Carmen Griñán-Lisón, Pablo Hernández-Camarero, María Ángel García

Publikováno v: Scientific Reports
Digibug. Repositorio Institucional de la Universidad de Granada
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Scientific Reports, Vol 9, Iss 1, Pp 1-17 (2019)

Cancer stem cells (CSCs) subpopulation within the tumour is responsible for metastasis and cancer relapse. Here we investigate in vitro and in vivo the effects of a pancreatic (pro)enzyme mixture composed of Chymotrypsinogen and Trypsinogen (PRP) on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f35632133992f96468d4f0b90270b0c3
https://pubmed.ncbi.nlm.nih.gov/31388092

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A formulation of pancreatic pro-enzymes provides potent anti-tumour efficacy: a pilot study focused on pancreatic and ovarian cancer

Autor: Julian Norman Kenyon, María Ángel García, Shorena Nadaraia-Hoke, Ralf Brandt, Macarena Perán, Elena López-Ruiz, Juan A. Marchal

Publikováno v: Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)

Proteolytic enzymes have shown efficacy in cancer therapy. We present a combination of the two pro-enzymes Trypsinogen and Chymotrypsinogen A with potent in vitro and in vivo anti-tumour efficacy. A synergetic anti-tumour effect for Trypsinogen and C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaa0c38d7b3a1ce533d27f5bb0a2bac9
https://doi.org/10.1038/s41598-017-14571-x

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In vitro treatment of carcinoma cell lines with pancreatic (pro)enzymes suppresses the EMT programme and promotes cell differentiation

Autor: María Ángel García, Julian Norman Kenyon, Macarena Perán, Juan A. Marchal, David Tosh

Publikováno v: Cellular Oncology. 36:289-301

Background Previous research has suggested a putative utility of pancreatic (pro)enzymes in cancer treatment. The aim of the present study was to investigate the in vitro effects of a mixture of two pancreatic pro-enzymes, i.e., Chymotrypsinogen and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::397bcb32daea83ec8ee0cfb152271a35
https://doi.org/10.1007/s13402-013-0134-8

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Outcome Measures Following Sonodynamic Photodynamic Therapy – A Case Series

Autor: Julian Norman Kenyon, Richard James Fuller

Publikováno v: Current Drug Therapy. 6:12-16

Sonodynamic Photodynamic Therapy (SPDT) is a novel cancer treatment approach using a photosensitive agent (Sonnelux-1) with reported ultrasound-activated properties. The sensitiser is administered prior to a cycle of light and low-intensity ultrasoun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2f1da445e19e2adeb196581fc3e667c9
https://doi.org/10.2174/157488511794079059

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Activated Cancer Therapy Using Light and Ultrasound - A Case Series of Sonodynamic Photodynamic Therapy in 115 Patients Over a 4 Year Period

Autor: Julian Norman Kenyon, Richard James Fulle, Thomas Joseph Lewis

Publikováno v: Current Drug Therapy. 4:179-193

Activated Ca ncer Ther apy ( ACT), al so know n a s Sonodyna mic Phot odynamic Ther apy ( SPDT) i s a nove l therapeutic modality that utilises a non-toxic photosensitive agent with reported ultrasound-activated properties. SPDT has previously demons

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e5d8026f59e168de29ff6c04ffc65077
https://doi.org/10.2174/157488509789055036

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Influence of yeast-derived 1,3/1,6 glucopolysaccharide on circulating cytokines and chemokines with respect to upper respiratory tract infections

Autor: Hamza Butt, Julian Norman Kenyon, Paul S. Noakes, Richard Fuller, Philip C. Calder, Tat Shing Yam

Publikováno v: Nutrition (Burbank, Los Angeles County, Calif.). 28(6)

Objective Wellmune WGP is a food supplement containing a refined 1,3/1,6 glucopolysaccharide that improves the antimicrobial activity of the innate immune cells by the priming of lectin sites. This study aimed to investigate whether Wellmune decrease

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea6796f772c7a2d37644666782c5a020
https://pubmed.ncbi.nlm.nih.gov/22465901

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