Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Julian Maggio"'
Preclinical Efficacy and Toxicology Evaluation of RAC1 Inhibitor 1A-116 in Human Glioblastoma Models
Autor:
Georgina A. Cardama, Julian Maggio, Lucas Valdez Capuccino, Nazareno Gonzalez, Valentina Matiller, Hugo H. Ortega, German R. Perez, Ignacio A. Demarco, Eduardo Spitzer, Daniel E. Gomez, Pablo Lorenzano Menna, Daniel F. Alonso
Publikováno v:
Cancers, Vol 14, Iss 19, p 4810 (2022)
Malignant gliomas are the most common primary central nervous system tumor in adults. Despite current therapeutics, these tumors are associated with poor prognosis and a median survival of 16 to 19 months. This highlights the need for innovative trea
Externí odkaz:
https://doaj.org/article/7dd353e1f55b48e59a63af8bb499eeb8
Autor:
Romina Armando, Maia Cabrera, Roman Vilarullo, Patricio Chinestrad, Julian Maggio, Camila Paderta, Pablo Lorenzano Menna, Daniel Gomez, Diego Mengual Gómez
Publikováno v:
Oncology Reports. 48
Autor:
Julian Maggio, Maia Diana Eliana Cabrera, Patricio Chinestrad, Pablo Lorenzano Menna, Daniel E. Gomez, Diego Luis Mengual Gómez, Romina Gabriela Armando, Marina Pifano
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 40:5858-5867
The parvulin PIN1 (peptidyl-prolyl cis-trans isomerase NIMA-interacting 1), is the only enzyme capable of isomerizing prolines of phospho-Serine/Threonine-Proline motifs. PIN1 binds to a subset of proteins and plays an essential role in regulating pr
Autor:
María Cecilia Sanmartin, Daniel E. Gomez, Diego Luis Mengual Gómez, Julian Maggio, Romina Gabriela Armando
Publikováno v:
Clinical Genetics. 96:3-16
Telomeropathies involve a wide variety of infrequent genetic diseases caused by mutations in the telomerase maintenance mechanism or the DNA damage response (DDR) system. They are considered a family of rare diseases that often share causes, molecula
Autor:
Pablo Lorenzano Menna, Daniel F. Alonso, Daniel E. Gomez, Julian Maggio, Georgina Alexandra Cardama, C. Rolfo, Nazareno González
Publikováno v:
Critical reviews in oncology, hematology
Rac1 GTPase signaling pathway has a critical role in the regulation of a plethora of cellular functions governing cancer cell behavior. Recently, it has been shown a critical role of Rac1 in the emergence of resistance mechanisms to cancer therapy. T
Autor:
Daniel E. Gomez, Nazareno González, P. Lorenzano Menna, Georgina Alexandra Cardama, Julian Maggio
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
International Journal of Oncology
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
International Journal of Oncology
Rho GTPases are key molecular switches controlling the transduction of external signals to cytoplasmic and nuclear effectors. In the last few years, the development of genetic and pharmacological tools has allowed a more precise definition of the spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3390efa163afd6df6330851f0915472b
https://www.spandidos-publications.com/10.3892/ijo.2017.4093
https://www.spandidos-publications.com/10.3892/ijo.2017.4093