Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Julian Lange"'
Autor:
Adrianna K. San Roman, Helen Skaletsky, Alexander K. Godfrey, Neha V. Bokil, Levi Teitz, Isani Singh, Laura V. Blanton, Daniel W. Bellott, Tatyana Pyntikova, Julian Lange, Natalia Koutseva, Jennifer F. Hughes, Laura Brown, Sidaly Phou, Ashley Buscetta, Paul Kruszka, Nicole Banks, Amalia Dutra, Evgenia Pak, Patricia C. Lasutschinkow, Colleen Keen, Shanlee M. Davis, Angela E. Lin, Nicole R. Tartaglia, Carole Samango-Sprouse, Maximilian Muenke, David C. Page
Publikováno v:
Cell Genomics, Vol 4, Iss 1, Pp 100462- (2024)
Summary: Somatic cells of human males and females have 45 chromosomes in common, including the “active” X chromosome. In males the 46th chromosome is a Y; in females it is an “inactive” X (Xi). Through linear modeling of autosomal gene expres
Externí odkaz:
https://doaj.org/article/f7bcee4c14104a018d0e1ee125035ddd
Autor:
Jannick Kappelmann, Bianca Klein, Mathias Papenfuß, Julian Lange, Bastian Blombach, Ralf Takors, Wolfgang Wiechert, Tino Polen, Stephan Noack
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2021)
Wild-type C. glutamicum ATCC 13032 is known to possess two enzymes with anaplerotic (C4-directed) carboxylation activity, namely phosphoenolpyruvate carboxylase (PEPCx) and pyruvate carboxylase (PCx). On the other hand, C3-directed decarboxylation ca
Externí odkaz:
https://doaj.org/article/6a4f2dda03994522b0f66057fd7584c0
Autor:
Alexander Widger, Shantha K. Mahadevaiah, Julian Lange, Elias ElInati, Jasmin Zohren, Takayuki Hirota, Sarai Pacheco, Andros Maldonado-Linares, Marcello Stanzione, Obah Ojarikre, Valdone Maciulyte, Dirk G. de Rooij, Attila Tóth, Ignasi Roig, Scott Keeney, James M.A. Turner
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
ATR kinase is required for meiosis in non-mammalian model organisms. Here the authors demonstrate, using a tissue-specific knockout approach, that ATR is also essential for male meiosis in mouse, regulating meiotic recombination and synapsis.
Externí odkaz:
https://doaj.org/article/b92089ad88aa43c8bc4181f628f431ba
Autor:
Sarai Pacheco, Andros Maldonado-Linares, Marina Marcet-Ortega, Cristina Rojas, Ana Martínez-Marchal, Judit Fuentes-Lazaro, Julian Lange, Maria Jasin, Scott Keeney, Oscar Fernández-Capetillo, Montserrat Garcia-Caldés, Ignasi Roig
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
ATR kinase is required for meiosis in non-mammalian model organisms. Here the authors demonstrate, using a hypomorphic Atr mutation and chemical inhibition, that ATR is also essential for male meiosis in mouse, regulating meiotic recombination and sy
Externí odkaz:
https://doaj.org/article/fe3547f3e3bf408bb594225884c01810
Autor:
Julian Lange, Felix Müller, Kerstin Bernecker, Nicolaus Dahmen, Ralf Takors, Bastian Blombach
Publikováno v:
Biotechnology for Biofuels, Vol 10, Iss 1, Pp 1-13 (2017)
Abstract Background A future bioeconomy relies on the efficient use of renewable resources for energy and material product supply. In this context, biorefineries have been developed and play a key role in converting lignocellulosic residues. Although
Externí odkaz:
https://doaj.org/article/4312edf7a9b14a12ad758c4fc72072fd
Autor:
Devanshi Jain, Cem Meydan, Julian Lange, Corentin Claeys Bouuaert, Nathalie Lailler, Christopher E Mason, Kathryn V Anderson, Scott Keeney
Publikováno v:
PLoS Genetics, Vol 13, Iss 8, p e1006964 (2017)
Transcriptional silencing by heritable cytosine-5 methylation is an ancient strategy to repress transposable elements. It was previously thought that mammals possess four DNA methyltransferase paralogs-Dnmt1, Dnmt3a, Dnmt3b and Dnmt3l-that establish
Externí odkaz:
https://doaj.org/article/cde3a330bdbf428189a795ce541b1643
Publikováno v:
PLoS Genetics, Vol 11, Iss 3, p e1005017 (2015)
Most mutations that compromise meiotic recombination or synapsis in mouse spermatocytes result in arrest and apoptosis at the pachytene stage of the first meiotic prophase. Two main mechanisms are thought to trigger arrest: one independent of the dou
Externí odkaz:
https://doaj.org/article/0a8d9027b54845ff9a76ca50d5056d5d
Autor:
Uddipta Biswas, Cornelia Wetzker, Julian Lange, Eleni G Christodoulou, Michael Seifert, Andreas Beyer, Rolf Jessberger
Publikováno v:
PLoS Genetics, Vol 9, Iss 12, p e1003985 (2013)
Cohesin subunit SMC1β is specific and essential for meiosis. Previous studies showed functions of SMC1β in determining the axis-loop structure of synaptonemal complexes (SCs), in providing sister chromatid cohesion (SCC) in metaphase I and thereaft
Externí odkaz:
https://doaj.org/article/c427810c0be1444aaca079fdf39c48a4
Autor:
Julian Lange, Bastian Alt, Rolf Neubert, Volker Hussennether, Marcos Gimenes Christianini de Abreu
Publikováno v:
2021 AEIT HVDC International Conference (AEIT HVDC).
A highly experienced level of quality testing capabilities for HVDC converters is one of the key pre-requisites in guaranteeing operational reliability and availability of HVDC transmission schemes. In this paper we combine both aspects by introducin
Publikováno v:
Cell
SummaryNumerous DNA double-strand breaks (DSBs) arise during meiosis to initiate homologous recombination. These DSBs are usually repaired faithfully, but here we uncover a new type of mutational event in which deletions form via joining of ends from