Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Julian L. Klosowiak"'
Autor:
Simon Moradian, MD, Julian L. Klosowiak, MD, PhD, Michael J. Boctor, BS, Tariq Issa, BS, Seong Park, BA, Gregory A. Dumanian, MD
Publikováno v:
Plastic and Reconstructive Surgery, Global Open, Vol 11, Iss 4, p e4947 (2023)
Background:. Umbilical hernia repair is a common surgical procedure without a universally accepted means of repair. We introduce a novel surgical technique for open primary umbilical hernia repair, using strips of polypropylene mesh as sutures to ach
Externí odkaz:
https://doaj.org/article/d286a0ebaa594955a9d3c828e82583bd
Autor:
Michael J. Boctor, Julian L. Klosowiak, Simon Moradian, Iulianna Taritsa, Gregory A. Dumanian, Jason H. Ko
Publikováno v:
Neurosurgical Focus: Video. 8:V12
In the United States, an estimated 185,000 individuals undergo amputation of their upper or lower limb. This results in residual limb pain in up to 85% of cases. Targeted muscle reinnervation (TMR) is a technique that has been shown to prevent sympto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd5293582f5c5f860fd3da6994effe93
https://doi.org/10.3171/2022.10.focvid2293
https://doi.org/10.3171/2022.10.focvid2293
Publikováno v:
The Cleft Palate-Craniofacial Journal. 56:168-176
Objective:The concept of mandibular catch-up growth is often quoted in the literature regarding Pierre Robin sequence (PRS). We endeavored to perform a systematic review of whether the literature supports this concept.Design:Systematic review.Interve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8400262913aca1eab115f6fff7f369b0
https://doi.org/10.1177/1055665618774025
https://doi.org/10.1177/1055665618774025
Autor:
John R. Yates, Julian L. Klosowiak, Steven I. Reed, Tony Hunter, Michael E. French, Aaron Aslanian
Publikováno v:
Journal of Biological Chemistry. 292:10398-10413
Homologous to E6AP C-terminal (HECT) ubiquitin (Ub) ligases (E3s) are a large class of enzymes that bind to their substrates and catalyze ubiquitination through the formation of a Ub thioester intermediate. The mechanisms by which these E3s assemble
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7efeabb05a60dc2353f3e592442e4c0d
https://doi.org/10.1074/jbc.m117.789479
https://doi.org/10.1074/jbc.m117.789479
Autor:
Kyle P. Smith, Eric C. Landahl, Douglas M. Freymann, Pamela J. Focia, Sarah E. Rice, Julian L. Klosowiak, Srinivas Chakravarthy
Publikováno v:
J Struct Biol
Dysfunction in mitochondrial dynamics is believed to contribute to a host of neurological disorders and has recently been implicated in cancer metastasis. The outer mitochondrial membrane adapter protein Miro functions in the regulation of mitochondr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dab9a53a55f4ea860f8efa77ffbd26c6
https://doi.org/10.1016/j.jsb.2020.107656
https://doi.org/10.1016/j.jsb.2020.107656
Autor:
Srinivas Chakravarthy, Pamela J. Focia, Sarah E. Rice, Eric C. Landahl, Douglas M. Freymann, Julian L. Klosowiak
Publikováno v:
EMBO reports. 14:968-974
Miro is a highly conserved calcium-binding GTPase at the regulatory nexus of mitochondrial transport and autophagy. Here we present crystal structures comprising the tandem EF hand and carboxy terminal GTPase (cGTPase) domains of Drosophila Miro. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21ee6d5875fb6d13a7b19fadc282ad9b
https://doi.org/10.1038/embor.2013.151
https://doi.org/10.1038/embor.2013.151
Autor:
Michael E. French, Sungjin Park, Sarah E. Rice, Julian L. Klosowiak, Kyle P. Smith, Douglas M. Freymann, Pamela J. Focia
Publikováno v:
Scientific Reports
Hereditary Parkinson’s disease is commonly caused by mutations in the protein kinase PINK1 or the E3 ubiquitin ligase Parkin, which function together to eliminate damaged mitochondria. PINK1 phosphorylates both Parkin and ubiquitin to stimulate ubi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ed2f7236d9568d60b29078b9c8977a6
Autor:
Julian L. Klosowiak, Douglas M. Freymann, Pamela J. Focia, Yongbo Zhang, Kyle P. Smith, Sarah E. Rice
Publikováno v:
Biophysical Journal. 112:177a-178a
Mitochondria motility and dynamics are tightly linked. Dysfunction in mitochondrial dynamics cause a host of neurological disorders. The outer mitochondrial membrane protein Miro contains two GTPase domains that control mitochondrial dynamics. While
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a00b1027f41806c33c627b6873f8cf7
https://doi.org/10.1016/j.bpj.2016.11.982
https://doi.org/10.1016/j.bpj.2016.11.982
Publikováno v:
European Journal of Physics. 29:607-617
We describe the construction and operation of three low-cost schlieren imaging systems that can be fabricated using surplus optics and 80/20, an aluminium extrusion based construction system. Each system has a different optical configuration. The low
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::088310d4e5f078f16ebb055f2921ef19
https://doi.org/10.1088/0143-0807/29/3/020
https://doi.org/10.1088/0143-0807/29/3/020
Autor:
Julian L. Klosowiak, Srinivas Chakravarthy, Sarah E. Rice, Pamela J. Focia, Douglas M. Freymann
Publikováno v:
Biophysical Journal. 108(2)
The outer mitochondrial membrane protein Miro is a highly conserved calcium-binding GTPase that is at the regulatory nexus of several processes, including mitochondrial transport and autophagy. Miro attaches mitochondria to the microtubule-based moto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::830d1e4c6e181337fb8741c46619b9ca