Zobrazeno 1 - 10
of 140
pro vyhledávání: '"Julian K-C Ma"'
Autor:
Jonathan Menary, Matthew Hobbs, Sara Mesquita de Albuquerque, Agata Pacho, Pascal M W Drake, Alison Prendiville, Julian K-C Ma, Sebastian S Fuller
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0229952 (2020)
Plant molecular farming (PMF) is a convenient and cost-effective way to produce high-value recombinant proteins that can be used in the production of a range of health products, from pharmaceutical therapeutics to cosmetic products. New plant breedin
Externí odkaz:
https://doaj.org/article/0a4c287ad4544298b6ca876012ab6109
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0229877 (2020)
Rhabdoviruses are enveloped negative-sense RNA viruses that have numerous biotechnological applications. However, recovering plant rhabdoviruses from cDNA remains difficult due to technical difficulties such as the need for concurrent in planta expre
Externí odkaz:
https://doaj.org/article/490ccf5a082c4302b73563577e37ef2c
Autor:
Ilaria Pepponi, Elena Stylianou, Craig van Dolleweerd, Gil Reynolds Diogo, Matthew J Paul, Pascal M W Drake, Julian K-C Ma, Rajko Reljic
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60855 (2013)
Protein-based vaccine development faces the difficult challenge of finding robust yet non-toxic adjuvants suitable for humans. Here, using a molecular engineering approach, we have developed a molecular platform for generating self-adjuvanting immuno
Externí odkaz:
https://doaj.org/article/a54955682eab410c875dfcb51483f5c1
Autor:
Pia Uetz, Kathrin Göritzer, Emil Vergara, Stanislav Melnik, Clemens Grünwald-Gruber, Rudolf Figl, Ala-Eddine Deghmane, Elisabetta Groppelli, Rajko Reljic, Julian K.-C. Ma, Eva Stöger, Richard Strasser
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Introduction: Prolyl-4-hydroxylases (P4H) catalyse the irreversible conversion of proline to hydroxyproline, constituting a common posttranslational modification of proteins found in humans, plants, and microbes. Hydroxyproline residues can be furthe
Externí odkaz:
https://doaj.org/article/cdbf7b764cf24126b27c521c73bfe88c
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 6856 (2024)
Secretory IgA (SIgA) presents a promising avenue for mucosal immunotherapy yet faces challenges in expression, purification, and stability. IgA exists in two primary isotypes, IgA1 and IgA2, with IgA2 further subdivided into two common allotypes: IgA
Externí odkaz:
https://doaj.org/article/70145e12ff014004b7354b963e336b67
Autor:
Kathrin Göritzer, Melanie Grandits, Clemens Grünwald-Gruber, Rudolf Figl, Sébastien Mercx, Catherine Navarre, Julian K-C. Ma, Audrey Y-H. Teh
Publikováno v:
Frontiers in Plant Science, Vol 13 (2022)
Molecular pharming in plants offers exciting possibilities to address global access to modern biologics. However, differences in the N-glycosylation pathway including the presence of β(1,2)-xylose and core α(1,3)-fucose can affect activity, potency
Externí odkaz:
https://doaj.org/article/f5ca13225d094f4b86c70ce5aa04f9eb
Autor:
Laura A. Ridgley, Nicole Falci Finardi, Benjamin B. Gengenbach, Patrick Opdensteinen, Zack Croxford, Julian K.‐C. Ma, Mark Bodman‐Smith, Johannes F. Buyel, Audrey Y.‐H. Teh
Publikováno v:
Plant Biotechnology Journal. 21:1254-1269
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d55927a7a9be6d759e502fd64a9c6e1a
https://doi.org/10.1111/pbi.14034
https://doi.org/10.1111/pbi.14034
Autor:
Haiyan Sun, Ming Yang, Huafang Lai, Biswas Neupane, Audrey Y.-H. Teh, Collin Jugler, Julian K.-C. Ma, Herta Steinkellner, Fengwei Bai, Qiang Chen
Publikováno v:
Viruses; Volume 15; Issue 5; Pages: 1156
Antibody-dependent enhancement of infection (ADE) is clinically relevant to Dengue virus (DENV) infection and poses a major risk to the application of monoclonal antibody (mAb)-based therapeutics against related flaviviruses such as the Zika virus (Z
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e5f9012b52328df2bc9d54d7da10957
Autor:
Melanie Grandits, Clemens Grünwald-Gruber, Silke Gastine, Joseph F. Standing, Rajko Reljic, Audrey Y-H. Teh, Julian K-C. Ma
Publikováno v:
Frontiers in Plant Science. 14
IntroductionBroadly neutralising antibodies are promising candidates for preventing and treating Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome (HIV/AIDS), as an alternative to or in combination with antiretroviral therapy (ART). The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcbb0e7aa391cfeed89d4d937d69cd71
The dawn of antibody therapy was heralded by the rise of IgG therapeutics. However, other antibody classes are at our disposal—one of the most exciting is IgA and is the most abundant antibody class within humans. Unlike IgG, it is uniquely special
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0acf8809960259ac16d1b53a085b841
https://mts.intechopen.com/articles/show/title/engineering-secretory-iga-against-infectious-diseases
https://mts.intechopen.com/articles/show/title/engineering-secretory-iga-against-infectious-diseases
