Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Julian Egger"'
Autor:
Peter Bretscher, Julian Egger, Abdijapar Shamshiev, Martin Trötzmüller, Harald Köfeler, Erick M Carreira, Manfred Kopf, Stefan Freigang
Publikováno v:
EMBO Molecular Medicine, Vol 7, Iss 5, Pp 593-607 (2015)
Abstract Exposure of biological membranes to reactive oxygen species creates a complex mixture of distinct oxidized phospholipid (OxPL) species, which contribute to the development of chronic inflammatory diseases and metabolic disorders. While the a
Externí odkaz:
https://doaj.org/article/451f2b5b908f4644a3d51fd5c3454b01
Autor:
Jason M. Link, Carl Pelz, Patrick J. Worth, Sydney Owen, Dove Keith, Ellen M. Langer, Alison Grossblatt-Wait, Allison L. Creason, Julian Egger, Hannah Holly, Isabel English, Kevin MacPherson, Motoyuki Tsuda, Jeremy Goecks, Emek Demir, Adel Kardosh, Charles D. Lopez, Brett C. Sheppard, Alex Guimaraes, Brian Brinkerhoff, Terry K. Morgan, Gordon Mills, Jonathan Brody, Rosalie C. Sears
Background and AimsMetastatic pancreatic adenocarcinoma (mPDAC) is lethal, yet a subset of patients who have metastatic disease that spreads only to the lung have better outcomes. We identified unique transcriptomic and immune features that distingui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2fe88444e2e445222eb69ba2c01bf6e
https://doi.org/10.1101/2022.05.04.490552
https://doi.org/10.1101/2022.05.04.490552
Publikováno v:
Organic Process Research & Development. 20:1540-1545
Homogeneous conditions for the palladium-catalyzed cyanation of aryl halides were developed. This new system features a broad scope of aryl chlorides and bromides, uses 2-propanol or 1-butanol as solvent, and is readily scalable. The same conditions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c685778b60e110957df3e4cf2dec7eb6
https://doi.org/10.1021/acs.oprd.6b00229
https://doi.org/10.1021/acs.oprd.6b00229
Autor:
Manfred Kopf, Erick M. Carreira, Stefan Freigang, Stefan Fischer, Peter A. Bretscher, Julian Egger
Publikováno v:
Org Lett
Organic Letters
Organic Letters
An efficient synthesis of 15-deoxy-Δ12,14-prostaglandin J2 (15d-PGJ2, 1) is reported. The route described allows for diversification of the parent structure to prepare seven analogues of 1 in which the positioning of electrophilic sites is varied. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a7613b6421374c3776080b336bd5ec9
http://pubs.acs.org/doi/10.1021/acs.orglett.5b02181
http://pubs.acs.org/doi/10.1021/acs.orglett.5b02181
Publikováno v:
J Am Chem Soc
Epoxyisoprostanes EI (1) and EC (2) are effective inhibitors of the secretion of proinflammatory cytokines IL-6 and IL-12. In detailed studies toward the investigation of the molecular mode of action of these structures, a highly potent lactone (3) d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a4e74bf6ed41d2773141b991be5e3d7
Publikováno v:
Angewandte Chemie. 125:5490-5494
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5ffd5565c167f3e19d0ae9d02673455
https://doi.org/10.1002/ange.201300739
https://doi.org/10.1002/ange.201300739
Publikováno v:
ChemInform. 47
Homogeneous conditions for the palladium-catalyzed cyanation of aryl halides were developed. This new system features a broad scope of aryl chlorides and bromides, uses 2-propanol or 1-butanol as solvent, and is readily scalable. The same conditions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::416df64ea879715fa99de9f4808a18db
https://doi.org/10.1002/chin.201652150
https://doi.org/10.1002/chin.201652150
Autor:
Erick M. Carreira, Julian Egger
Publikováno v:
ChemInform. 45
Covering: up to April 2013 Transition metal-catalyzed insertion of carbenes and nitrenes into C–H bonds has become a powerful tool for the construction of C–C and C–N bonds in the synthesis of complex natural products. In this Highlight, a sele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7236e0c78a9182a595c86b138656fafd
https://doi.org/10.1002/chin.201433250
https://doi.org/10.1002/chin.201433250
Autor:
Erick M. Carreira, Julian Egger
Publikováno v:
Natural product reports. 31(4)
Covering: up to April 2013 Transition metal-catalyzed insertion of carbenes and nitrenes into C–H bonds has become a powerful tool for the construction of C–C and C–N bonds in the synthesis of complex natural products. In this Highlight, a sele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5af0c2b45ebde92c897fd53b25b630b
https://pubmed.ncbi.nlm.nih.gov/24589531
https://pubmed.ncbi.nlm.nih.gov/24589531
Publikováno v:
Angewandte Chemie (International ed. in English). 52(20)
Anti-inflammatory: The efficient and general synthetic route to the elusive epoxyisoprostanoid phospholipids PECPC and PEIPC, along with the isoprostanoids EC and EI, relies on a number of stereo- and chemoselective steps, including a C[BOND]H insert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c9054a5456a8f1889bcbf937f45a7e6
https://pubmed.ncbi.nlm.nih.gov/23592365
https://pubmed.ncbi.nlm.nih.gov/23592365