Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Julian Echave"'
Autor:
María Laura Marcos, Julian Echave
Publikováno v:
Current Research in Structural Biology, Vol 2, Iss , Pp 156-163 (2020)
Protein structures do not evolve uniformly, but the degree of structure divergence varies among sites. The resulting site-dependent structure divergence patterns emerge from a process that involves mutation and selection, which may both, in principle
Externí odkaz:
https://doaj.org/article/d04cf53a6d2a40ddaec39cef3c6b52ed
Autor:
Julian Echave
Publikováno v:
PeerJ, Vol 9, p e11330 (2021)
Studying the effect of perturbations on protein structure is a basic approach in protein research. Important problems, such as predicting pathological mutations and understanding patterns of structural evolution, have been addressed by computational
Externí odkaz:
https://doaj.org/article/85ca6fec87ff4e60865ee3bb2fc5c41b
Publikováno v:
PLoS Biology, Vol 14, Iss 5, p e1002452 (2016)
Functional residues in proteins tend to be highly conserved over evolutionary time. However, to what extent functional sites impose evolutionary constraints on nearby or even more distant residues is not known. Here, we report pervasive conservation
Externí odkaz:
https://doaj.org/article/24b25204093a4fa6bf23f0afd7e8f226
Autor:
María Laura Marcos, Julian Echave
Publikováno v:
PeerJ, Vol 3, p e911 (2015)
In protein evolution, due to functional and biophysical constraints, the rates of amino acid substitution differ from site to site. Among the best predictors of site-specific rates are solvent accessibility and packing density. The packing density me
Externí odkaz:
https://doaj.org/article/9bd21c7bc799419095486a1975e3089f
Autor:
Guadalupe Alvarez, Thu Le, Nathan Wong, Julian Echave, Thomas C. Pochapsky, Eliana K. Asciutto
Publikováno v:
Biochemistry. 61:1790-1800
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96c5b403913c712c3f7bae97cd9ef8bb
https://doi.org/10.1021/acs.biochem.2c00233
https://doi.org/10.1021/acs.biochem.2c00233
Autor:
Julian Echave, José Campos-Martínez
Publikováno v:
Molecular Physics. 98:1729-1735
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59123b4fc4b445b08e17165ffeb04d8b
https://doi.org/10.1080/00268970050177620
https://doi.org/10.1080/00268970050177620
Publikováno v:
The journal of physical chemistry. B. 110(23)
We have obtained AMBER94 force-field parameters for the TTQ cofactor of the enzyme methylamine dehydrogenase (MADH). This enzyme catalyzes the oxidation of methylamine to produce formaldehyde and ammonia. In the rate-determining step of the catalyzed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::827c533e713333cc1e133f38267ce433
https://pubmed.ncbi.nlm.nih.gov/16771436
https://pubmed.ncbi.nlm.nih.gov/16771436
Autor:
Julian Echave
Publikováno v:
Trends in Evolutionary Biology. 1:2
Textbook of Structural Biology By Anders Liljas, Lars Liljas, Jure Piskur, Goran Lindblom, Poul Nissen, and Morten Kjeldgaard Publisher: World Scientific Publishing Co. Pte. Ltd. Number of Pages: 572 Publication Year: 2009 ISBN-10: 981-277-208-1 ISBN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c5bec59d8850bc17dfcbdae9a2b9ea8
https://doi.org/10.4081/eb.2009.e2
https://doi.org/10.4081/eb.2009.e2
Publikováno v:
Scopus-Elsevier
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::b1bb1f70977a7b1d2b55073461abb4de
http://www.scopus.com/inward/record.url?eid=2-s2.0-36448999085&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-36448999085&partnerID=MN8TOARS
Publikováno v:
Physical Biology; Apr2015, Vol. 12 Issue 2, p1-1, 1p