Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Julian E Sale"'
Autor:
Neil Bate, Christos G Savva, Peter C E Moody, Edward A Brown, Sian E Evans, Jonathan K Ball, John W R Schwabe, Julian E Sale, Nicholas P J Brindle
Publikováno v:
PLoS Pathogens, Vol 18, Iss 7, p e1010733 (2022)
Emerging SARS-CoV-2 variants are creating major challenges in the ongoing COVID-19 pandemic. Being able to predict mutations that could arise in SARS-CoV-2 leading to increased transmissibility or immune evasion would be extremely valuable in develop
Externí odkaz:
https://doaj.org/article/1c450b5c20754a42910056edeab3abf1
Autor:
Kouji Hirota, Eiichiro Sonoda, Takuo Kawamoto, Akira Motegi, Chikahide Masutani, Fumio Hanaoka, Dávid Szüts, Shigenori Iwai, Julian E Sale, Alan Lehmann, Shunichi Takeda
Publikováno v:
PLoS Genetics, Vol 6, Iss 10 (2010)
Replicative DNA polymerases are frequently stalled by DNA lesions. The resulting replication blockage is released by homologous recombination (HR) and translesion DNA synthesis (TLS). TLS employs specialized TLS polymerases to bypass DNA lesions. We
Externí odkaz:
https://doaj.org/article/8da1f6191d1b461e8ef6c6a2e071181b
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9008 (2010)
Monoubiquitination of the DNA sliding clamp, PCNA, plays a central role in the control of damage bypass during replication. By combining a widely-spaced FRET donor/acceptor pair (CFP and mRFP) with spectral imaging, we have developed a simple method
Externí odkaz:
https://doaj.org/article/33548a1b2941455ab31decc9072c0100
Autor:
Makoto Nakahara, Eiichiro Sonoda, Kuniharu Nojima, Julian E Sale, Katsuya Takenaka, Koji Kikuchi, Yoshihito Taniguchi, Kyoko Nakamura, Yoshiki Sumitomo, Ronan T Bree, Noel F Lowndes, Shunichi Takeda
Publikováno v:
PLoS Genetics, Vol 5, Iss 1, p e1000356 (2009)
Homologous recombination (HR) is initiated by DNA double-strand breaks (DSB). However, it remains unclear whether single-strand lesions also initiate HR in genomic DNA. Chicken B lymphocytes diversify their Immunoglobulin (Ig) V genes through HR (Ig
Externí odkaz:
https://doaj.org/article/3e79b77828f24a779ab5fa03288bf0e4
Publikováno v:
Critical Reviews in Biochemistry and Molecular Biology. 57:412-442
During replication, folding of the DNA template into non-B-form secondary structures provides one of the most abundant impediments to the smooth progression of the replisome. The core replisome collaborates with multiple accessory factors to ensure t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af10d765ec19b0d08a5fe256ca5fe1f9
https://doi.org/10.1080/10409238.2022.2121803
https://doi.org/10.1080/10409238.2022.2121803
Autor:
Jun Nakamura, James A. Swenberg, Masami Watanabe, Shunichi Takeda, Minoru Takata, Douglas K. Bishop, Mitsuyoshi Yamazoe, Julian E. Sale, David A.F. Gillespie, Jean-Marie Buerstedde, Hiroshi Arakawa, Eiichiro Sonoda, April M. Luke, Keizo Tano, Ayumi Nakamura, John R. Ridpath
Formaldehyde is an aliphatic monoaldehyde and is a highly reactive environmental human carcinogen. Whereas humans are continuously exposed to exogenous formaldehyde, this reactive aldehyde is a naturally occurring biological compound that is present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::133d5ae3c34c1b87681a5e0bbb705420
https://doi.org/10.1158/0008-5472.c.6496742
https://doi.org/10.1158/0008-5472.c.6496742
Autor:
Jun Nakamura, James A. Swenberg, Masami Watanabe, Shunichi Takeda, Minoru Takata, Douglas K. Bishop, Mitsuyoshi Yamazoe, Julian E. Sale, David A.F. Gillespie, Jean-Marie Buerstedde, Hiroshi Arakawa, Eiichiro Sonoda, April M. Luke, Keizo Tano, Ayumi Nakamura, John R. Ridpath
Supplementary Figure 1 from Cells Deficient in the FANC/BRCA Pathway Are Hypersensitive to Plasma Levels of Formaldehyde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b1095106e3b03f58cc9dcda62c8d998
https://doi.org/10.1158/0008-5472.22371317
https://doi.org/10.1158/0008-5472.22371317
Autor:
Pierre Murat, Consuelo Perez, Alastair Crisp, Patrick van Eijk, Simon H. Reed, Guillaume Guilbaud, Julian E. Sale
Publikováno v:
Science advances. 8(45)
The interplay between active biological processes and DNA repair is central to mutagenesis. Here, we show that the ubiquitous process of replication initiation is mutagenic, leaving a specific mutational footprint at thousands of early and efficient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd9ca74860a9b797a039223e0e0cbfa7
https://pubmed.ncbi.nlm.nih.gov/36351018
https://pubmed.ncbi.nlm.nih.gov/36351018
Autor:
Julian E, Sale
Publikováno v:
Nature structuralmolecular biology. 29(9)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c3407e5f41de6284591b9fc451517e79
https://pubmed.ncbi.nlm.nih.gov/36127467
https://pubmed.ncbi.nlm.nih.gov/36127467
Autor:
Julian E. Sale, Alastair Crisp, Cara B. Eldridge, Finian J. Allen, Rodrigo A. Grandy, Ludovic Vallier
Publikováno v:
Stem Cell Reports
Summary The ability of human induced pluripotent stem cells (hiPSCs) to differentiate in vitro to each of the three germ layer lineages has made them an important model of early human development and a tool for tissue engineering. However, the factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0d9ba43813a50567ccb044d62b4dc41
https://doi.org/10.1016/j.stemcr.2020.08.003
https://doi.org/10.1016/j.stemcr.2020.08.003