Zobrazeno 1 - 10 of 90 pro vyhledávání: '"Julian Dyson"'
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Akademický článek
Nanoscale Colocalization of NK Cell Activating and Inhibitory Receptors Controls Signal Integration
Autor: David Tomaz, Pedro Matos Pereira, Nadia Guerra, Julian Dyson, Keith Gould, Ricardo Henriques
Publikováno v: Frontiers in Immunology, Vol 13 (2022)
Natural killer (NK) cell responses depend on the balance of signals from inhibitory and activating receptors. However, how the integration of antagonistic signals occurs upon NK cell–target cell interaction is not fully understood. Here we provide
Externí odkaz: https://doaj.org/article/94db0b8324664817a1f5cf288ba0a58a
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Nanoscale Colocalization of NK Cell Activating and Inhibitory Receptors Controls Signal Integration
Autor: Pedro M. Pereira, Keith G. Gould, Julian Dyson, David Tomaz, Ricardo Henriques, Nadia Guerra
Publikováno v: Frontiers in immunology. 13
Natural killer (NK) cell responses depend on the balance of signals from inhibitory and activating receptors. However, how the integration of antagonistic signals occurs upon NK cell–target cell interaction is not fully understood. Here we provide
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b40573fb58740fa272dad65ab1b15b2
https://pubmed.ncbi.nlm.nih.gov/35720315
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8
Reduced Regulatory T Cell Diversity in NOD Mice Is Linked to Early Events in the Thymus
Autor: Julian Dyson, Oliver A. Garden, Kenneth Blake, Cristina Ferreira, Donald B. Palmer
Publikováno v: The Journal of Immunology. 192:4145-4152
The thymic natural regulatory T cell (Treg) compartment of NOD mice is unusual in having reduced TCR diversity despite normal cellularity. In this study, we show that this phenotype is attributable to perturbations in early and late stages of thymocy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93140565bc1c0998c63283a847941fb6
https://doi.org/10.4049/jimmunol.1301600
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9
Intramolecular polyspecificity in CD4 T-cell recognition of Ad-restricted epitopes of proteoglycan aggrecan
Autor: Anna L. Furmanski, Julian Dyson, Katie Lowes, Jane Falconer, Wan-Fai Ng, John H. Robinson
Publikováno v: Immunology. 142:101-110
T-cell recognition of MHC–peptide complexes shows a high degree of polyspecificity extending to recognition of a large number of structurally unrelated peptides. Examples of polyspecificity reported to date are confined to recognition of epitopes f
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88696f90d237422134602b2c0517ca55
https://doi.org/10.1111/imm.12238
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Local immunostimulation leading to rejection of accepted male skin grafts by female mice as a model for cancer immunotherapy
Autor: Christophe Lurquin, Jean-François Baurain, Nicolas van Baren, Isabelle Jacquemart, Christophe Bourdeaux, Julian Dyson, Jacques Van Snick, Catherine Uyttenhove, Thierry Boon, Bernard Lethe, Francis Brasseur
Publikováno v: Proceedings of the National Academy of Sciences. 111:3502-3507
Significance Many cancer patients mount a spontaneous T-lymphocyte response against their tumor. In metastatic progressing patients, this response has evidently been incomplete. Moreover, it has stalled, and an immunosuppressive environment appears t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fe99553d16a5c9f41cd5771e428e911
https://doi.org/10.1073/pnas.1401115111
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