Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Julian D. Watts"'
Autor:
Teresa DiColandrea, Charles C. Bascom, Jason M. Winget, Julian D. Watts, Michael K. Robinson, Michael R. Hoopmann, Tom Huggins, Robert L. Moritz, Robert J. Isfort
Publikováno v:
Journal of Dermatological Science. 78:173-180
Background The barrier function of the epidermis is integral to personal well-being, and defects in the skin barrier are associated with several widespread diseases. Currently there is a limited understanding of system-level proteomic changes during
Autor:
Robert L. Moritz, Julian D. Watts, David Shteynberg, Eric W. Deutsch, Zhi Sun, Micheleen M. Harris, Tadashi Yamamoto, Gilbert S. Omenn, Terry Farrah
Publikováno v:
Journal of Proteome Research
Journal of Proteome Research; Vol 13
Journal of Proteome Research; Vol 13
The kidney, urine, and plasma proteomes are intimately related: proteins and metabolic waste products are filtered from the plasma by the kidney and excreted via the urine, while kidney proteins may be secreted into the circulation or released into t
Autor:
M. Christiansen, Paola Picotti, Eric W. Deutsch, Jing Chen, Mi-Youn Brusniak, D. Campbell, Ruedi Aebersold, Lukas Reiter, C. Kwok, Simon Letarte, Hector Ramos, Julian D. Watts
Publikováno v:
Molecular & Cellular Proteomics. 8:S44-S52
C.1
Autor:
Ruedi Aebersold, Lukas N. Mueller, Julian D. Watts, Hamid Mirzaei, Mi Youn Brusniak, Simon Letarte
Publikováno v:
Molecular & Cellular Proteomics. 8:1934-1946
As the application for quantitative proteomics in the life sciences has grown in recent years, so has the need for more robust and generally applicable methods for quality control and calibration. The reliability of quantitative proteomics is tightly
Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins
Autor:
Damaris Bausch-Fluck, Ruedi Aebersold, Ralph Schiess, Julian D. Watts, Miriam Bibel, Bernd Wollscheid, Christine Henderson, Robert V. O’Brien
Publikováno v:
Nature Biotechnology. 27:378-386
Although the classification of cell types often relies on the identification of cell surface proteins as differentiation markers, flow cytometry requires suitable antibodies and currently permits detection of only up to a dozen differentiation marker
Autor:
Jonathan A. Cooper, Anjali Teckchandani, Julian D. Watts, Christine Henderson, Natalie Toida, Jake Goodchild, Bernd Wollscheid
Publikováno v:
The Journal of Cell Biology
Clathrin-associated endocytic adapters recruit cargoes to coated pits as a first step in endocytosis. We developed an unbiased quantitative proteomics approach to identify and quantify glycoprotein cargoes for an endocytic adapter, Dab2. Surface leve
Autor:
James S. Eddes, Paul Shannon, Mi Youn Brusniak, Lukas N. Mueller, Julian D. Watts, Olga Vitek, Christopher J. Kemp, David S. Campbell, Hui Zhang, Alexander Schmidt, Simon Letarte, Ruedi Aebersold, Karen S. Kelly-Spratt, Hollis Lau
Publikováno v:
Clinical Proteomics. 4:105-116
IntroductionA proof-of-concept demonstration of the use of label-free quantitative glycoproteomics for biomarker discovery workflow is presented in this paper, using a mouse model for skin cancer as an example.Materials and MethodsBlood plasma was co
Publikováno v:
Molecular & Cellular Proteomics. 7:813-823
Absolute quantification of peptides by mass spectrometry requires a reference, frequently using heavy isotope-coded peptides as internal standards. These peptides have traditionally been generated by chemical stepwise synthesis. Recently a new way to
Autor:
Jimmy K. Eng, Leigh Anderson, Heidi Zhang, Ted Holzman, Li Chia Feng, Tao Liu, Richard D. Smith, Martin W. McIntosh, Brian D. Piening, J.F. Keane, Regine M. Schoenherr, Chen Wei Lin, Amanda G. Paulovich, Kelly Cooke, Jeffrey R. Whiteaker, Julian D. Watts, Travis D. Lorentzen, Matthew Fitzgibbon, David G. Camp, Ruihua Fang, Hui Zhang
Publikováno v:
Journal of Proteome Research. 6:828-836
Multiple approaches for simplifying the serum proteome have been described. These techniques are generally developed across different laboratories, samples, mass spectrometry platforms, and analysis tools. Hence, comparing the available schemes is im
Publikováno v:
Current Opinion in Immunology. 16:337-344
Recent technological advances in genomics, proteomics and bioinformatics have offered new insights into the molecular mechanisms that underlie lymphocyte signaling and function, and the development of new tools in these areas has opened up new avenue