Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Julian D. Schwab"'
Autor:
Silke D. Werle, Nensi Ikonomi, Ludwig Lausser, Annika M. T. U. Kestler, Felix M. Weidner, Julian D. Schwab, Julia Maier, Malte Buchholz, Thomas M. Gress, Angelika M. R. Kestler, Hans A. Kestler
Publikováno v:
npj Systems Biology and Applications, Vol 9, Iss 1, Pp 1-17 (2023)
Abstract Pancreatic neuroendocrine tumors (PanNETs) are a rare tumor entity with largely unpredictable progression and increasing incidence in developed countries. Molecular pathways involved in PanNETs development are still not elucidated, and speci
Externí odkaz:
https://doaj.org/article/4ccc6dba9fcc4072b055b2958bdc1426
Autor:
Silke D. Werle, Nensi Ikonomi, Julian D. Schwab, Johann M. Kraus, Felix M. Weidner, K. Lenhard Rudolph, Astrid S. Pfister, Rainer Schuler, Michael Kühl, Hans A. Kestler
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 1603-1617 (2022)
Controlling phenotypical landscapes is of vital interest to modern biology. This task becomes highly demanding because cellular decisions involve complex networks engaging in crosstalk interactions. Previous work on control theory indicates that smal
Externí odkaz:
https://doaj.org/article/d0b5b7f5c42942bfa222393dd1bb697b
Autor:
Julian D. Schwab, Johannes Schobel, Silke D. Werle, Axel Furstberger, Nensi Ikonomi, Robin Szekely, Patrick Thiam, Rolf Huhne, Niels Jahn, Rainer Schuler, Peter Kuhn, Martin Holderried, Florian Steger, Manfred Reichert, Udo X. Kaisers, Angelika M. R. Kestler, Thomas Seufferlein, Hans A. Kestler
Publikováno v:
IEEE Access, Vol 9, Pp 83863-83875 (2021)
Mobile applications have increasingly entered the healthcare sector. Besides being daily companions, so-called mHealth applications have the potential to enable individuals to collect data, document issues, and share them with healthcare professional
Externí odkaz:
https://doaj.org/article/4531d3c5b4ef4ab98b1324c2f34d74e3
Autor:
Julian D. Schwab, Nensi Ikonomi, Silke D. Werle, Felix M. Weidner, Hartmut Geiger, Hans A. Kestler
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 5321-5332 (2021)
Regulatory dependencies in molecular networks are the basis of dynamic behaviors affecting the phenotypical landscape. With the advance of high throughput technologies, the detail of omics data has arrived at the single-cell level. Nevertheless, new
Externí odkaz:
https://doaj.org/article/02ac09438f424fe7b43b675397ba34ea
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 571-582 (2020)
Boolean network models are one of the simplest models to study complex dynamic behavior in biological systems. They can be applied to unravel the mechanisms regulating the properties of the system or to identify promising intervention targets. Since
Externí odkaz:
https://doaj.org/article/317b3aba4f5b4a39855c3aaabf83f8d7
Autor:
Alan Bareiß, Günalp Uzun, Marco Mikus, Matthias Becker, Karina Althaus, Nicole Schneiderhan-Marra, Axel Fürstberger, Julian D. Schwab, Hans A. Kestler, Martin Holderried, Peter Martus, Katja Schenke-Layland, Tamam Bakchoul
Publikováno v:
Viruses, Vol 15, Iss 1, p 65 (2022)
As the Corona Disease 2019 (COVID-19) caused by SARS-CoV-2 persists, vaccination is one of the key measures to contain the spread. Side effects (SE) from vaccination are one of the reasons for reluctance to vaccinate. We systematically investigated s
Externí odkaz:
https://doaj.org/article/726e46b3c0b5464b985372ccc3aa6ad4
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Hematopoietic stem cells (HSCs) provide all types of blood cells during the entire life of the organism. HSCs are mainly quiescent and can eventually enter the cell cycle to differentiate. HSCs are maintained and tightly regulated in a particular env
Externí odkaz:
https://doaj.org/article/aafbedae06a048a2909ac48696bea262
Autor:
Julian D. Schwab, Hans A. Kestler
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
A common approach to address biological questions in systems biology is to simulate regulatory mechanisms using dynamic models. Among others, Boolean networks can be used to model the dynamics of regulatory processes in biology. Boolean network model
Externí odkaz:
https://doaj.org/article/9f88d70d3e84403cab2872416492ba87
Autor:
Christoph Müssel, Nensi Ikonomi, Silke D Werle, Felix M Weidner, Markus Maucher, Julian D Schwab, Hans A Kestler
Publikováno v:
Bioinformatics. 38:4893-4900
MotivationBiological processes are complex systems with distinct behaviour. Despite the growing amount of available data, knowledge is sparse and often insufficient to investigate the complex regulatory behaviour of these systems. Moreover, different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b2354f4443e44532d242fe5a0e5700d
https://doi.org/10.1093/bioinformatics/btac623
https://doi.org/10.1093/bioinformatics/btac623
Autor:
Bakchoul, Alan Bareiß, Günalp Uzun, Marco Mikus, Matthias Becker, Karina Althaus, Nicole Schneiderhan-Marra, Axel Fürstberger, Julian D. Schwab, Hans A. Kestler, Martin Holderried, Peter Martus, Katja Schenke-Layland, Tamam
Publikováno v:
Viruses; Volume 15; Issue 1; Pages: 65
As the Corona Disease 2019 (COVID-19) caused by SARS-CoV-2 persists, vaccination is one of the key measures to contain the spread. Side effects (SE) from vaccination are one of the reasons for reluctance to vaccinate. We systematically investigated s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::c5a0c21bcb44069ccdcacee1414775b3