Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Julian D. Gross"'
Autor:
Julian D. Gross, Catherine J. Pears
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
mTORC1 and AMPK are mutually antagonistic sensors of nutrient and energy status that have been implicated in many human diseases including cancer, Alzheimer’s disease, obesity and type 2 diabetes. Starved cells of the social amoeba Dictyostelium di
Externí odkaz:
https://doaj.org/article/1c581b558f814ea6bb852af8ae9181dd
Autor:
Catherine J, Pears, Julian D, Gross
Publikováno v:
Microbiology (Reading, England). 167(3)
The social amoeba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::13bd4ac990ec8ae531a0bc11475afe74
https://pubmed.ncbi.nlm.nih.gov/33646931
https://pubmed.ncbi.nlm.nih.gov/33646931
Autor:
Julian D. Gross, Catherine J. Pears
Publikováno v:
Microbiology. 167
The social amoeba Dictyostelium discoideum is a versatile organism that is unusual in alternating between single-celled and multi-celled forms. It possesses highly-developed systems for cell motility and chemotaxis, phagocytosis, and developmental pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37797a0dc477be35b3978b45d9e0aa7f
https://doi.org/10.1099/mic.0.001040
https://doi.org/10.1099/mic.0.001040
Autor:
Julian D. Gross, Catherine J. Pears, Fu-Sheng Chang, Yuntao Wang, Antony Galione, Phillip Dmitriev
Publikováno v:
BMC Biology, Vol 18, Iss 1, Pp 1-16 (2020)
BMC Biology
BMC Biology
BackgroundTwo-pore channels (TPCs) release Ca2+from acidic intracellular stores and are implicated in a number of diseases, but their role in development is unclear. The social amoebaDictyostelium discoideumproliferates as single cells that aggregate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6930ec07798c2f49a70bcdb00f3a00b1
https://doi.org/10.1186/s12915-019-0735-4
https://doi.org/10.1186/s12915-019-0735-4
Publikováno v:
Differentiation. 66:71-80
During culmination of Dictyostelium aggregates, prespore and prestalk cells undergo terminal differentiation to form spores and a cellular stalk. Disruption of the cell-fate gene stkA leads to a phenotype in which all the cells destined to become spo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a743960d85247ece2e93f87ff883467
https://doi.org/10.1046/j.1432-0436.2000.660202.x
https://doi.org/10.1046/j.1432-0436.2000.660202.x
Publikováno v:
Journal of Biological Chemistry. 273:30859-30862
Disruption of either the RDEA or REGA genes leads to rapid development in Dictyostelium. The RDEA gene product displays homology to certain H2-type phosphotransferases, while REGA encodes a cAMP phosphodiesterase with an associated response regulator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2c1eabb78b4dcbb0e07a0733579bd2e
https://doi.org/10.1074/jbc.273.47.30859
https://doi.org/10.1074/jbc.273.47.30859
Autor:
Fabiana Horn, Julian D. Gross
Publikováno v:
FEMS Microbiology Letters. 137:275-278
Cyclic AMP-dependent protein kinase (PKA) is required for aggregation of starved amoebae during development of Dictyostelium discoideum as well as for prespore gene expression and for maturation of stalk cells and spores. It has not been clear until
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35204a1e4775127f974250d61c0151af
https://doi.org/10.1111/j.1574-6968.1996.tb08118.x
https://doi.org/10.1111/j.1574-6968.1996.tb08118.x
Autor:
Katalin Pinter, Julian D. Gross
Publikováno v:
Differentiation. 59:201-206
We investigated the possible involvement of Ca2+ in cell-type-specific gene expression in Dictyostelium discoideum. Aggregates dissociated and shaken in suspension in buffer containing ethylene glycol tetra-acetic acid (EGTA) for 2 h showed a sharp d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa220d81607846819547dee4dd400ae0
https://doi.org/10.1046/j.1432-0436.1995.5940201.x
https://doi.org/10.1046/j.1432-0436.1995.5940201.x
Publikováno v:
Cell. 75:321-327
The weak base ammonia is implicated in a number of key processes in Dictyostelium development, notably aggregation and culmination. To determine its intracellular site of action, we compared its biological potency with that of other weak bases. All t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41f9498a2ba65c74c3f9e5737a481a11
https://doi.org/10.1016/0092-8674(93)80073-n
https://doi.org/10.1016/0092-8674(93)80073-n
Autor:
Kei Inouye, Julian D. Gross
Publikováno v:
Development. 118:523-526
In ‘slugger’ mutants of Dictyostelium discoideum, aggregates of cells remain for an abnormally long time in the migratory phase under conditions where wild-type aggregates form fruiting bodies. In the present work, we have examined the relationsh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51be0007fe479e65e67cdb08bb437afe
https://doi.org/10.1242/dev.118.2.523
https://doi.org/10.1242/dev.118.2.523